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anti-Zinc Finger CCCH-Type Containing 12A (ZC3H12A) Antibodies

ZC3H12A is an MCP1 (CCL2\; MIM 158105)-induced protein that acts as a transcriptional activator and causes cell death of cardiomyocytes, possibly via induction of genes associated with apoptosis.[supplied by OMIM, Mar 2008].. Additionally we are shipping ZC3H12A Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ZC3H12A 230738 Q5D1E7
ZC3H12A 313587 A0JPN4
ZC3H12A 80149 Q5D1E8
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Top anti-ZC3H12A Antibodies at antibodies-online.com

Showing 10 out of 33 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, IHC (p), WB ZC12A antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human spleen tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the ZC12A antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated. ZC12A Antibody (Center) western blot analysis in HepG2 cell line lysates (35 µg/lane). This demonstrates the ZC12A antibody detected the ZC12A protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated EIA, WB   0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated ICC, IF, IP, IHC, WB WB Image ZC3H12A antibody detects ZC3H12A protein by western blot analysis. Various whole cell extracts (30 μg) were separated by 7.5% SDS-PAGE, and the membrane was blotted with ZC3H12A antibody , diluted at a dilution of 1:1000. ICC/IF Image Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using ZC3H12A, antibody at 1:200 dilution. 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated ICC, WB   100 μL Log in to see 8 to 10 Days
$507.83
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated IF, WB 100 μL Log in to see 6 to 11 Days
$485.71
Details
Human Rabbit Un-conjugated IHC, ELISA, WB 400 μL Log in to see 6 Days
$457.14
Details
Human Rabbit Un-conjugated ELISA   200 μL Log in to see 8 to 10 Days
$713.17
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of ZC3H12A in Raji cell lysate with ZC3H12A antibody at (A) 1 and (B) 2 µg/mL. 0.1 mg Log in to see 2 to 3 Days
$330.00
Details

ZC3H12A Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine) ,


Rat (Rattus) ,


Human , , ,
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, , , , ,

Top referenced anti-ZC3H12A Antibodies

  1. Human Polyclonal ZC3H12A Primary Antibody for EIA, IHC (p) - ABIN955634 : Skalniak, Mizgalska, Zarebski, Wyrzykowska, Koj, Jura: Regulatory feedback loop between NF-kappaB and MCP-1-induced protein 1 RNase. in The FEBS journal 2009 (PubMed)
    Show all 5 references for ABIN955634

  2. Human Polyclonal ZC3H12A Primary Antibody for EIA, WB - ABIN501151 : Zhou, Azfer, Niu, Graham, Choudhury, Adamski, Younce, Binkley, Kolattukudy: Monocyte chemoattractant protein-1 induces a novel transcription factor that causes cardiac myocyte apoptosis and ventricular dysfunction. in Circulation research 2006 (PubMed)

More Antibodies against ZC3H12A Interaction Partners

Mouse (Murine) Zinc Finger CCCH-Type Containing 12A (ZC3H12A) interaction partners

  1. Overexpression of MCPIP1 induced apoptosis.

  2. MCPIP1 is the target of mmu-miR (show MLXIP Antibodies)-27-5p.

  3. MCPIP1-MSCs also expressed increased levels of proteins involved in angiogenesis, autophagy, and induction of differentiation

  4. This studies demonstrated that MCPIP1 is an important mediator of minocycline-induced protection from brain ischemia.

  5. Data indicate that MCPIP1 (also termed Regnase-1, encoded by Zc3h12a) knockdown enhanced interleukin-17 (IL-17 (show IL17A Antibodies))-mediated signaling.

  6. MCPIP expression in the ischemic myocardium protects against adverse cardiac remodeling and dysfunction following myocardial infarction

  7. both in vivo and in vitro experiments demonstrate that the transcription factors STAT6 (show STAT6 Antibodies) and KLF4 (show KLF4 Antibodies) implement IL-4 (show IL4 Antibodies)-induced M2 polarization via the dual catalytic activities of MCPIP.

  8. Findings reveal that differential regulation of mRNAs by Regnase-1 and Roquin (show RC3H1 Antibodies) depends on their translation status and enables elaborate control of inflammation.

  9. Roquin (show RC3H1 Antibodies) inhibited T(H)17 cell differentiation and acted together with the endoribonuclease regnase-1 to repress target mRNA encoding the T(H)17 cell-promoting factors IL-6 (show IL6 Antibodies), ICOS (show ICOS Antibodies), c-Rel (show NFkBP65 Antibodies), IRF4 (show IRF4 Antibodies), IkappaBNS (show NFKBID Antibodies) and IkappaBzeta (show NFKBIZ Antibodies).

  10. MCPIP1 deficiency in mice results in severe anemia related to autoimmune mechanisms.

Human Zinc Finger CCCH-Type Containing 12A (ZC3H12A) interaction partners

  1. Suggest that MCPIP1 may play an important role in cholesterol induced damage in endothelial cells.

  2. Findings show increased MCP1P expression in a model of Ischemia/Reperfusion Injury (I/R) and suggest a vital role for MCPIP1 in cell migration and apoptosis, resulting in increased angiogenesis and apoptosis during the late stages of I/R.

  3. In white blood cells from patients with SLE, MCPIP1 expression was elevated, and its expression correlated positively with the IFN score and negatively with the miR (show MLXIP Antibodies)-146a transcript level.

  4. demonstrated induction of MCPIP1 in human fibroblasts embedded in the stress-released 3-D collagen matrix, which occurred through activation of mitogen-activated protein kinases, phosphoinositide 3-kinase, and NF-kappaB (show NFKB1 Antibodies)

  5. In this review we summarize current progress regarding the specific characteristics of sequences and structures in the 3' untranslated regions of mRNAs that are recognized by tristetraproline (show ZFP36 Antibodies), Roquins, and Regnase-1.

  6. miR (show MLXIP Antibodies)-139-mediated downregulation of MCPIP1 promotes IL-6 (show IL6 Antibodies) expression in osteoarthritis.

  7. MCPIP1 and MCPIP4 (show ZC3H12D Antibodies) form a complex but they act independently in regulation of IL-6 (show IL6 Antibodies) mRNA degradation.

  8. Data show that regulator of G protein signaling 2 (RGS2 (show RGS2 Antibodies)) was stabilized by deubiquitinase monocyte chemotactic protein-induced protein 1 (MCPIP1).

  9. MCPIP1 may suppress hepatitis C virus replication and hepatitis C virus-mediated proinflammatory responses with infection, which might contribute to the regulation of host defense against the infection and virus-induced inflammation.

  10. MCPIP1-associated USP10 (show USP10 Antibodies) is essential for negative regulation of NF-kappaB (show NFKB1 Antibodies) activation.

ZC3H12A Antigen Profile

Protein Summary

ZC3H12A is an MCP1 (CCL2\; MIM 158105)-induced protein that acts as a transcriptional activator and causes cell death of cardiomyocytes, possibly via induction of genes associated with apoptosis.

Gene names and symbols associated with ZC3H12A

  • zinc finger CCCH-type containing 12A (ZC3H12A) antibody
  • zinc finger CCCH type containing 12A (Zc3h12a) antibody
  • BC036563 antibody
  • dJ423B22.1 antibody
  • MCPIP antibody
  • MCPIP1 antibody
  • RGD1306776 antibody
  • RP3-423B22.1 antibody

Protein level used designations for ZC3H12A

zinc finger CCCH-type containing 12A , MCP-1 treatment-induced protein , MCP-induced protein 1 , ribonuclease ZC3H12A , zinc finger CCCH domain-containing protein 12A , Zinc finger CCCH domain-containing protein 12A , MCP induced protein 1

GENE ID SPECIES
419618 Gallus gallus
456757 Pan troglodytes
608211 Canis lupus familiaris
713604 Macaca mulatta
100395231 Callithrix jacchus
100461560 Pongo abelii
100481016 Ailuropoda melanoleuca
230738 Mus musculus
313587 Rattus norvegicus
80149 Homo sapiens
535344 Bos taurus
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