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Acts as a transcriptional repressor of the GATA3 promoter. Additionally we are shipping Zinc Finger CCCH-Type Containing 8 Proteins (2) and many more products for this protein.
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Human Polyclonal ZC3H8 Primary Antibody for EIA, WB - ABIN955638
Hwang, Ho: Regulation of thymocyte homeostasis by Fliz1. in Immunology 2002
Show all 3 references for ABIN955638
Human Polyclonal ZC3H8 Primary Antibody for FACS, WB - ABIN655410
Lamesch, Li, Milstein, Fan, Hao, Szabo, Hu, Venkatesan, Bethel, Martin, Rogers, Lawlor, McLaren, Dricot, Borick, Cusick, Vandenhaute, Dunham, Hill, Vidal: hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. in Genomics 2007
Show all 2 references for ABIN655410
Fliz1 binds specifically to a negative cis (show CISH Antibodies)-acting element in the intronic regulatory region of GATA-3 (show GATA3 Antibodies) and, when overexpressed, can function as a transcriptional repressor of the GATA-3 (show GATA3 Antibodies) promoter in vitro and in vivo.
Acts as a transcriptional repressor of the GATA3 promoter. Sequence-specific DNA-binding factor that binds to the 5'-AGGTCTC-3' sequence within the negative cis-acting element intronic regulatory region (IRR) of the GATA3 gene (By similarity). Induces thymocyte apoptosis when overexpressed, which may indicate a role in regulation of thymocyte homeostasis.
zinc finger CCCH domain-containing protein 8
, zinc finger CCCH type domain containing 8
, zinc finger CCCH-type containing 8
, zinc finger CCCH-type domain containing 8
, fetal liver zinc finger 1
, fetal liver zinc finger 1; putative zinc finger protein FLIZ1
, fetal liver zinc finger protein 1