Zinc Finger CCCH-Type Containing 14 (ZC3H14) ELISA Kits

ZC3H14 belongs to a family of poly(A)-binding proteins that influence gene expression by regulating mRNA stability, nuclear export, and translation (Kelly et al., 2007 [PubMed 17630287]).[supplied by OMIM, Mar 2010].. Additionally we are shipping ZC3H14 Antibodies (36) and ZC3H14 Proteins (3) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Mouse ZC3H14 ZC3H14 75553 Q8BJ05
Anti-Rat ZC3H14 ZC3H14 192359 Q7TMD5
Anti-Human ZC3H14 ZC3H14 79882 Q6PJT7
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More ELISA Kits for ZC3H14 Interaction Partners

Caenorhabditis elegans (C. elegans) Zinc Finger CCCH-Type Containing 14 (ZC3H14) interaction partners

  1. Study identified sut-2 as a gene required for tau neurotoxicity in C. elegans and cloned the sut-2 gene and found it encodes a novel sub-type of CCCH zinc finger protein conserved across animal phyla.

Human Zinc Finger CCCH-Type Containing 14 (ZC3H14) interaction partners

  1. ATP5G1 (show ATP5G1 ELISA Kits) turnover increases upon depletion of ZC3H14, double knockdown of ZC3H14 and the nonsense-mediated decay factor, UPF1 (show UPF1 ELISA Kits), rescues ATP5G1 (show ATP5G1 ELISA Kits) transcript levels. Furthermore, fractionation reveals an increase in the amount of ATP5G1 (show ATP5G1 ELISA Kits) pre-mRNA that reaches the cytoplasm when ZC3H14 is depleted and that ZC3H14 binds to ATP5G1 (show ATP5G1 ELISA Kits) pre-mRNA in the nucleus.

  2. we show here that human ZC3H14 can functionally substitute for dNab2 in fly neurons and can rescue defects in development and locomotion that are present in dNab2 null flies

  3. report a intellectual disability disease locus on chromosome 14q31.3 corresponding to mutation of the ZC3H14 gene that encodes a conserved polyadenosine RNA binding protein

  4. MSUT2 levels may influence neuronal vulnerability to tau toxicity and aggregation.

  5. New neuroprotective strategies targeting MSUT-2 that may be effective in modulating tau neurotoxicity in human tauopathy disorders.

  6. multiple transcripts encoding several ZC3H14 isoforms exist in vivo

ZC3H14 Antigen Profile

Antigen Summary

ZC3H14 belongs to a family of poly(A)-binding proteins that influence gene expression by regulating mRNA stability, nuclear export, and translation (Kelly et al., 2007

Gene names and symbols associated with ZC3H14

  • Protein SUT-2 (sut-2) antibody
  • zinc finger CCCH type containing 14 (Zc3h14) antibody
  • zinc finger CCCH-type containing 14 (ZC3H14) antibody
  • zinc finger CCCH-type containing 14 (zc3h14) antibody
  • 1010001P15Rik antibody
  • 1700016A15Rik antibody
  • 2700069A02RIK antibody
  • AU014748 antibody
  • MSUT-2 antibody
  • Npuk68 antibody
  • NY-REN-37 antibody
  • SUT2 antibody
  • UKp68 antibody

Protein level used designations for ZC3H14

zinc finger CCCH domain-containing protein 14 , zinc finger CCCH-type containing 14 , nuclear protein UKp68 , nuclear protein UKp83/UKp68 , mammalian suppressor of tau pathology-2 , renal carcinoma antigen NY-REN-37

GENE ID SPECIES
178847 Caenorhabditis elegans
75553 Mus musculus
192359 Rattus norvegicus
79882 Homo sapiens
480412 Canis lupus familiaris
511473 Bos taurus
423399 Gallus gallus
100158380 Xenopus laevis
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