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The zinc finger protein encoded by ZFPM2 is a widely expressed member of the FOG family of transcription factors. Additionally we are shipping and many more products for this protein.
Showing 10 out of 32 products:
Human Polyclonal ZFPM2 Primary Antibody for WB - ABIN442847
Klein, Misawa, Bravo-Egana, Vargas, Rosero, Piroso, Ichii, Umland, Zhijie, Tsinoremas, Ricordi, Inverardi, Domínguez-Bendala, Pastori: MicroRNA expression in alpha and beta cells of human pancreatic islets. in PLoS ONE 2013
Aberrant methylation status at the promoter CpG island shore of ZFPM2 gene may be associated with its gene transcription regulation in the tetralogy of fallot patients
Genetic Analysis of Venous Thromboembolism in UK Biobank Identifies the ZFPM2 Locus and Implicates Obesity as a Causal Risk Factor.
ZFPM2 is a glioma susceptibility gene, its genotype and expression showing associations with incidence and severity. The balancing selection acting on ZFPM2 may relate to its roles in multiple organ development or associated disease etiology.
Isolated congenital diaphragmatic hernia was the predominant phenotype observed in our ZFPM2 mutation patients.
screened a larger CTD population, which comprised 145 tetralogy of Fallot (TOF (show FEZF2 Antibodies)), 37 double-outlet ventricle outflow (DORV (show GDF1 Antibodies)), and 18 transposition of the great artery (TGA (show TBX1 Antibodies)), to investigate exon mutations as well as copy number variations in ZFPM2/FOG2
Whole exome sequencing identified independent missense mutations in FOG2 in two patients with 46,XY gonadal dysgenesis.
Findings indicate that zinc finger protein, multitype 2 protein (ZFPM2) plays a role in diaphragm and cardiovascular development.
Art27 (show UXT Antibodies) interacts with GATA4 (show GATA4 Antibodies), FOG2 and NKX2.5 (show NKX2-5 Antibodies) and is a novel co-repressor of cardiac genes.
our results provide strong evidence regarding the susceptibility of the ZFPM2 gene to the development of non-syndromic TOF/DORV.
FOG1 (show ZFPM1 Antibodies), FOG2 and GATA-6 (show GATA6 Antibodies) modulate the transcriptional up-regulation of HAMP (show HAMP Antibodies) in hepatocytes during inflammation.
identified key controls over corticothalamic projection neurons (CThPN) development and identify Fog2 as a critical control over CThPN diversity
FOG2 liver-specific knockout mice they exhibit enhanced insulin (show INS Antibodies) sensitivity and elevated hepatic TG accumulation, which were also reversed by Ad-PPARalpha (show PPARA Antibodies). The results demonstrate a novel function of hepatic FOG2 in insulin (show INS Antibodies) sensitivity and lipid metabolism through PPARalpha (show PPARA Antibodies).
Hypoxia-induced microRNA-429 promotes differentiation of osteoblastic cells by mediating ZFPM2 expression.
MicroRNA-200c Promotes Suppressive Potential of Myeloid-Derived Suppressor Cells by Modulating PTEN (show PTEN Antibodies) and FOG2 Expression
Results indicate that FOG-2/NuRD interaction is required for cardiomyocyte proliferation.
ATOH8 (show ATOH8 Antibodies), GATA4 (show GATA4 Antibodies), and FOG2 associate in a single complex
regulation of ovarian differentiation is dependent upon GATA4 (show GATA4 Antibodies) but not FOG2
data suggest a new mechanism for TGF-beta (show TGFB1 Antibodies)-induced Akt (show AKT1 Antibodies) activation through FOG2 down-regulation by miR (show MLXIP Antibodies)-200b/c, which can lead to glomerular mesangial hypertrophy in the progression of diabetic nephropathy
a new dynamics in which GATA-4 (show GATA4 Antibodies) may alter the activity of FOG-2 by influencing its SUMOylation status
gonadal loss of Fog2 resulted in an early partial block in male pathway and sex reversal
The zinc finger protein encoded by this gene is a widely expressed member of the FOG family of transcription factors. The family members modulate the activity of GATA family proteins, which are important regulators of hematopoiesis and cardiogenesis in mammals. It has been demonstrated that the protein can both activate and down-regulate expression of GATA-target genes, suggesting different modulation in different promoter contexts. A related mRNA suggests an alternatively spliced product but this information is not yet fully supported by the sequence.
, Friend of GATA2
, friend of GATA 2
, friend of GATA protein 2
, transcription factor GATA4, modulator of
, zinc finger protein 89B
, zinc finger protein ZFPM2
, zinc finger protein, multitype 2
, Friend of GATA 2
, friend of GATA-1 2
, friend of GATA-2