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anti-Zinc Finger Protein 163 (ZNF163) Antibodies

ZNF163 encodes a nuclear zinc finger protein that functions as a transcriptional repressor. Additionally we are shipping Zinc Finger Protein 163 Proteins (7) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ZNF163 14581 P70338
ZNF163 2672 Q99684
ZNF163 24388 Q07120
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Top anti-Zinc Finger Protein 163 Antibodies at antibodies-online.com

Showing 10 out of 54 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Dog Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated IF, WB Immunofluorescence of monoclonal antibody to GFI1 on HeLa cell (antibody concentration 10 µg/mL). Western Blot analysis of GFI1 expression in transfected 293T cell line by GFI1 monoclonal antibody (M01), clone 3G8. Lane 1: GFI1 transfected lysate(45 KDa). Lane 2: Non-transfected lysate. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Mouse Un-conjugated ELISA, WB Figure 1: Western blot analysis using GFI1 mAb against HEK293 (1) and GFI1 (AA: 2-250) -hIgGFc transfected HEK293 (2) cell lysate. 100 μL Log in to see 3 to 4 Days
$393.80
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Mouse Un-conjugated EIA, WB 0.1 mL Log in to see 6 to 8 Days
$335.50
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Dog Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated IHC (p), WB Anti-GFI1 antibody IHC staining of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN960185 concentration 5 ug/ml. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Mouse Un-conjugated WB   100 μL Log in to see 8 to 10 Days
$493.17
Details
Human Mouse Un-conjugated IHC (p)   100 μL Log in to see 8 to 10 Days
$493.17
Details

ZNF163 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine)


Human , ,
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Rat (Rattus)


Top referenced anti-Zinc Finger Protein 163 Antibodies

  1. Human Monoclonal ZNF163 Primary Antibody for IF, WB - ABIN394301 : Alcina, Fernández, Gonzalez, Catalá-Rabasa, Fedetz, Ndagire, Leyva, Guerrero, Arnal, Delgado, Lucas, Izquierdo, Matesanz: Tag-SNP analysis of the GFI1-EVI5-RPL5-FAM69 risk locus for multiple sclerosis. in European journal of human genetics : EJHG 2010 (PubMed)
    Show all 5 references for ABIN394301

  2. Human Monoclonal ZNF163 Primary Antibody for ELISA, WB - ABIN969174 : Dwivedi, Anderson, Tilley, May, Morris: Role of oncoprotein growth factor independent-1 (GFI1) in repression of 25-hydroxyvitamin D 1alpha-hydroxylase (CYP27B1): a comparative analysis in human prostate cancer and kidney cells. in The Journal of steroid biochemistry and molecular biology 2007 (PubMed)
    Show all 2 references for ABIN969174

  3. Dog (Canine) Polyclonal ZNF163 Primary Antibody for WB - ABIN2777468 : Duan, Zarebski, Montoya-Durango, Grimes, Horwitz: Gfi1 coordinates epigenetic repression of p21Cip/WAF1 by recruitment of histone lysine methyltransferase G9a and histone deacetylase 1. in Molecular and cellular biology 2005 (PubMed)

  4. Human Monoclonal ZNF163 Primary Antibody for EIA, WB - ABIN1109563 : Kimura, Wakamatsu, Suzuki, Ota, Nishikawa, Yamashita, Yamamoto, Sekine, Tsuritani, Wakaguri, Ishii, Sugiyama, Saito, Isono, Irie, Kushida, Yoneyama, Otsuka, Kanda, Yokoi, Kondo, Wagatsuma, Murakawa et al.: Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. ... in Genome research 2006 (PubMed)

More Antibodies against Zinc Finger Protein 163 Interaction Partners

Mouse (Murine) Zinc Finger Protein 163 (ZNF163) interaction partners

  1. these findings demonstrate a novel regulatory role of Gfi1 in the regulation of the Th1 (show HAND1 Antibodies)-type immune response.

  2. GFI1 proteins recruit the chromatin-modifying protein LSD1 (show KDM1A Antibodies), a member of the CoREST (show Rcor2 Antibodies) repressive complex, to epigenetically silence the endothelial program in haemogenic endothelium and allow the emergence of blood cells

  3. GFI1 inhibits NLRP3 (show NLRP3 Antibodies) inflammasome activation and IL-1beta (show IL1B Antibodies) secretion in macrophages

  4. Gfi-1 is linked to the erythroid gene regulatory network by repressing Id2 expression.

  5. results, supported by evidence from mouse models, identify GFI1 and GFI1B (show GFI1B Antibodies) as prominent medulloblastoma oncogenes and implicate 'enhancer hijacking' as an efficient mechanism driving oncogene (show RAB1A Antibodies) activation in a childhood cancer

  6. Gfi1 and gfi1b (show GFI1B Antibodies) repress rag transcription in plasmacytoid dendritic cells in vitro.

  7. Our data indicate that Gfi1 is required for hematopoietic precursors to withstand Notch1 (show NOTCH1 Antibodies) activation and to maintain Notch1 (show NOTCH1 Antibodies) dependent transcriptional programming to determine early T-lymphoid lineage identity.

  8. Data indicate that Gfi1 regulates the activation of type 2 innate lymphoid cells (ILC2 cells) cells during infection with Nippostrongylus brasiliensis.

  9. Gfi1 actively controls thymocyte IL-2 (show IL2 Antibodies) production, thereby shaping thymic generation of Treg cells.

  10. Compromised IL-7Ralpha expression in TGF-beta-receptor-deficient T cells was associated with increased expression of the Il7ra transcriptional repressor, Gfi-1.

Human Zinc Finger Protein 163 (ZNF163) interaction partners

  1. Gfi1 gene expression is regulated by cytokines in activated T cells.

  2. miR-495 directly interacts with the Gfi1 3'UTR to regulate Gfi1 at a post-transcriptional level and the expression level of miR-495 is inversely correlated with the Gfi1 protein level in medulloblastoma specimens.

  3. Gfi1 acts as a transcriptional repressor by recruiting histone-modifying enzymes to promoters and enhancers of target genes. Mutations of the C-terminal zinc finger domain causes congenital neutropenia. It may be involved in leukemia and lymphoma. Review.

  4. During infection, the incoming HCMV rapidly downregulates the GFI1 mRNA and protein in both wild-type cells and in cells in which EZH2 (show EZH2 Antibodies), NDY1/KDM2B (show KDM2B Antibodies) or JARID2 (show JARID2 Antibodies) were knocked down.

  5. Data shows that MYB regulates the expression of endogenous human GFI1.

  6. results, supported by evidence from mouse models, identify GFI1 and GFI1B (show GFI1B Antibodies) as prominent medulloblastoma oncogenes and implicate 'enhancer hijacking' as an efficient mechanism driving oncogene (show RAB1A Antibodies) activation in a childhood cancer

  7. Lymphoid progenitor cells from childhood acute lymphoblastic leukemia are functionally deficient and express high levels of the transcriptional repressor Gfi-1.

  8. GFI1 is repressed by p53 (show TP53 Antibodies)

  9. the expression of Gfi-1 contributes to SOCS1 (show SOCS1 Antibodies) silencing in AML (show RUNX1 Antibodies) cells through epigenetic modification, and suppression of histone methyltransferase can provide new insight in AML (show RUNX1 Antibodies) therapy.

  10. Studies indicate that Gfi1 recruits LSD1 (show KDM1A Antibodies) to p53 (show TP53 Antibodies) and dampens its activity by de-methylating p53 (show TP53 Antibodies) at C-terminal lysines to prevent immediate apoptosis.

Zinc Finger Protein 163 (ZNF163) Antigen Profile

Protein Summary

This gene encodes a nuclear zinc finger protein that functions as a transcriptional repressor. This protein plays a role in diverse developmental contexts, including hematopoiesis and oncogenesis. It functions as part of a complex along with other cofactors to control histone modifications that lead to silencing of the target gene promoters. Mutations in this gene cause autosomal dominant severe congenital neutropenia, and also dominant nonimmune chronic idiopathic neutropenia of adults, which are heterogeneous hematopoietic disorders that cause predispositions to leukemias and infections. Multiple alternatively spliced variants, encoding the same protein, have been identified for this gene.

Gene names and symbols associated with ZNF163

  • growth factor independent 1 (Gfi1) antibody
  • growth factor independent 1 transcription repressor (GFI1) antibody
  • growth factor independent 1 transcription repressor (Gfi1) antibody
  • AW495828 antibody
  • GFI-1 antibody
  • GFI1A antibody
  • Pal-1 antibody
  • Pal1 antibody
  • SCN2 antibody
  • ZNF163 antibody

Protein level used designations for ZNF163

growth factor independent protein 1 , zinc finger protein Gfi-1 , growth factor independence-1 , zinc finger protein 163 , growth factor independence 1 , Growth factor independent-1

GENE ID SPECIES
14581 Mus musculus
2672 Homo sapiens
490156 Canis lupus familiaris
24388 Rattus norvegicus
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