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Zinc Finger Protein 238 Proteins (ZNF238)

C2H2-type zinc finger proteins, such as ZNF238, act on the molecular level as transcriptional activators or repressors and are involved in chromatin assembly (Becker et al., 1997 [PubMed 9568537]).[supplied by OMIM, Jan 2011].. Additionally we are shipping Zinc Finger Protein 238 Antibodies (22) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ZNF238 10472 Q99592
Mouse ZNF238 ZNF238 30928 Q9WUK6
ZNF238 64619 Q9JKY3
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Top Zinc Finger Protein 238 Proteins at antibodies-online.com

Showing 4 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,487.00
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

ZNF238 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Rat (Rattus)

Top referenced Zinc Finger Protein 238 Proteins

  1. Human ZNF238 Protein expressed in Wheat germ - ABIN1326010 : Mao, Ladd, Gad, Rastetter, Johnson, Marzbani, Childs, Lu, Dang, Broussard, Stanton, Hanash, Disis: Mining the pre-diagnostic antibody repertoire of TgMMTV-neu mice to identify autoantibodies useful for the early detection of human breast cancer. in Journal of translational medicine 2014 (PubMed)

More Proteins for Zinc Finger Protein 238 (ZNF238) Interaction Partners

Human Zinc Finger Protein 238 (ZNF238) interaction partners

  1. repression of the CR2/CD21 (show CR2 Proteins) promoter can occur through one of the E-box motifs via recruitment of RP58.

  2. RP58 may act to favor neuronal differentiation and brain growth by coherently repressing multiple proneurogenic genes in a timely manner.

  3. Findings indicate that ZNF238 is a novel brain tumor suppressor and its reactivation in tumors could open a novel anticancer strategy.

Mouse (Murine) Zinc Finger Protein 238 (ZNF238) interaction partners

  1. Disruption of RP58 expression alters the differentiation of immature neurons and impairs their migration and positioning within the mouse cerebral cortex.

  2. RP58 represses Ngn2 (show NEUROG2 Proteins) transcription to regulate the Ngn2 (show NEUROG2 Proteins)-Rnd2 (show RND2 Proteins) pathway; Ngn2 (show NEUROG2 Proteins) knockdown rescued migration defects of the RP58(-/-) neurons.

  3. Rp58 is essential for the growth and organization of the cerebellum and regulates the development of both GABAergic and glutamatergic neurons.

  4. RP58 may act to favor neuronal differentiation and brain growth by coherently repressing multiple proneurogenic genes in a timely manner.

  5. This study showed that Cre recombinase (show RAG1 Proteins) expression under the control of the RP58 gene promoter is a feasible tool for conditional gene switching in post-mitotic multipolar migrating young neurons in the developing cerebral cortex.

  6. The authors report that a transcriptional factor, RP58, negatively regulates all four Id genes (Id1 (show ID1 Proteins)-Id4 (show ID4 Proteins)) in developing cerebral cortex.

  7. Data show that inhibition of ZNF238 (RP58) expression in mouse GNPs decreases the expression of the neuronal differentiation markers MAP2 and NeuN (show RBFOX3 Proteins) and downregulates the expression of the cell cycle arrest protein p27 (show CDKN1B Proteins), a regulator of GNP differentiation.

  8. The combined systems approach identified RP58 as an effector included in MyoD (show MYOD1 Proteins)-activated positive feedback and enabling progression of skeletal myogenesis by repressing expression of Id2 and Id3 (show ID3 Proteins), inhibitors of myogenesis.

  9. These results suggest that RP58 plays a crucial role in neuronal proliferation, migration, and differentiation in the developing cerebral cortex.

  10. Interestingly, co-transfection with simiRP58 (show ZBTB42 Proteins) and RP58 induced changes in the localization patterns of both proteins.

Zinc Finger Protein 238 (ZNF238) Protein Profile

Protein Summary

C2H2-type zinc finger proteins, such as ZNF238, act on the molecular level as transcriptional activators or repressors and are involved in chromatin assembly (Becker et al., 1997

Gene names and symbols associated with ZNF238

  • zinc finger and BTB domain containing 18 (zbtb18)
  • zinc finger and BTB domain containing 18 (ZBTB18)
  • zinc finger and BTB domain containing 18 (Zbtb18)
  • zinc finger protein 238 (ZNF238)
  • zinc finger protein 238 (ZBTB18)
  • zinc finger protein 238 (Zfp238)
  • C2H2-171 protein
  • Rp58 protein
  • si:ch211-221n23.1 protein
  • TAZ-1 protein
  • Zbtb18 protein
  • Zfp238 protein
  • Znf238 protein

Protein level used designations for ZNF238

BTB/POZ domain protein ZF238 , novel zinc finger domain containing protein , zinc finger and BTB domain-containing protein 18 , zinc finger protein 238 , 58 kDa repressor protein , transcriptional repressor RP58 , translin-associated zinc finger protein 1 , zinc finger protein C2H2-171 , zfp-238 , rRP58

GENE ID SPECIES
100003157 Danio rerio
379751 Xenopus laevis
10472 Homo sapiens
30928 Mus musculus
428580 Gallus gallus
490376 Canis lupus familiaris
538793 Bos taurus
64619 Rattus norvegicus
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