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ZNF274 encodes a zinc finger protein containing five C2H2-type zinc finger domains, one or two Kruppel-associated box A (KRAB A) domains, and a leucine-rich domain. Additionally we are shipping Zinc Finger Protein 274 Antibodies (45) and many more products for this protein.
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A proximal promoter construct for the MAS (show MAS1 Proteins) gene was repressed by the SOX (show PIPOX Proteins) [SRY (show SRY Proteins) (sex-determining region on the Y chromosome) box] proteins SRY (show SRY Proteins), SOX2 (show SOX2 Proteins), SOX3 (show SOX3 Proteins) and SOX14 (show SOX14 Proteins), of which SRY (show SRY Proteins) is known to interact with the KRAB domain.
analysis of a KRAB domain-containing ZNF (ZNF274) that is involved in recruitment of the KAP1 (show CDKN3 Proteins) and SETDB1 (show SETDB1 Proteins) to specific regions of the human genome
KAP1 (show CDKN3 Proteins) functions to coordinate activities that dynamically regulate changes in histone modifications and deposition of HP1 (show DEFA1 Proteins) to establish a de novo microenvironment of heterochromatin, which is required for repression of gene transcription by KRAB-zfps.
This gene encodes a zinc finger protein containing five C2H2-type zinc finger domains, one or two Kruppel-associated box A (KRAB A) domains, and a leucine-rich domain. The encoded protein has been suggested to be a transcriptional repressor. It localizes predominantly to the nucleolus. Alternatively spliced transcript variants encoding different isoforms exist. These variants utilize alternative polyadenylation signals.
zinc finger protein 274
, KRAB zinc finger protein HFB101
, neurotrophin receptor-interacting factor homolog
, zinc finger protein HFB101
, zinc finger protein with KRAB and SCAN domains 19
, zinc finger protein zfp2