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Transcriptional repressor. Additionally we are shipping and many more products for this protein.
Showing 10 out of 60 products:
Human Polyclonal ZNF350 Primary Antibody for EIA, WB - ABIN955706
Liao, Tsai, Chang, Lee, Wang: RB·E2F1 complex mediates DNA damage responses through transcriptional regulation of ZBRK1. in The Journal of biological chemistry 2010
Show all 3 references for ABIN955706
Human Polyclonal ZNF350 Primary Antibody for WB - ABIN2774983
Desjardins, Belleau, Labrie, Ouellette, Bessette, Chiquette, Laframboise, Lépine, Lespérance, Pichette, Plante, Durocher: Genetic variants and haplotype analyses of the ZBRK1/ZNF350 gene in high-risk non BRCA1/2 French Canadian breast and ovarian cancer families. in International journal of cancer. Journal international du cancer 2007
Human Polyclonal ZNF350 Primary Antibody for ICC, IF - ABIN4367184
Hallen, Klein, Stoschek, Wehrmeyer, Nonhoff, Ralser, Wilde, Röhr, Schweiger, Zatloukal, Vingron, Lehrach, Konthur, Krobitsch: The KRAB-containing zinc-finger transcriptional regulator ZBRK1 activates SCA2 gene transcription through direct interaction with its gene product, ataxin-2. in Human molecular genetics 2010
villin directly interacts with a transcriptional corepressor and ligand of the Slug (show SNAI2 Antibodies) promoter, ZBRK1.
ZBRK1 suppresses renal cancer progression perhaps by regulating VHL (show VHL Antibodies) expression through formation of a complex with VHL (show VHL Antibodies) and p300 (show EP300 Antibodies) in renal cancer
MAGE (show MAGEB10 Antibodies) proteins bind to KAP1 (show CDKN3 Antibodies), a gene repressor and ubiquitin E3 ligase which also binds KRAB domain containing zinc finger transcription factors (KZNFs), and MAGE (show MAGEB10 Antibodies) expression may affect KZNF mediated gene regulation.
The secondary structure of the ZBRK1-DNA complex is found to be significantly altered from the standard B-DNA conformation.
results indicate that a loss of ZBRK1 contributes to the increased expression of KAP1 (show CDKN3 Antibodies), potentiating its role to enhance metastasis and invasion
promoter assays in two breast cancer cell lines identified two haplotypes (H11 and H12 (show HIST1H1C Antibodies)) stimulating significantly the expression of ZNF350 transcript compared with the common haplotype H8
ZBRK1 negatively regulates the HIV-1 LTR
high levels of gene activity in the genomic environment and the pre-deposition of repressive histone marks within a gene increase its susceptibility to KRAB/KAP1 (show CDKN3 Antibodies)-mediated repression
KRAB-containing zinc-finger transcriptional regulator, ZBRK1, an interaction partner of the SCA2 (show LY6E Antibodies) gene product ataxin-2 (show ATXN2 Antibodies).
RB.E2F1 complex plays a critical role in ZBRK1 transcriptional repression, and loss of this repression may contribute to cellular sensitivity of DNA damage, ultimately leading to carcinogenesis.
Transcriptional repressor. Binds to a specific sequence, 5'-GGGxxxCAGxxxTTT-3', within GADD45 intron 3 (By similarity).
KRAB zinc finger protein ZFQR
, zinc finger and BRCA1-interacting protein with a KRAB domain 1
, zinc finger protein ZBRK1
, zinc-finger protein ZBRK1
, zinc finger protein 350
, zinc finger protein 350-like