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anti-Zinc Finger Protein 36, C3H Type, Homolog (Mouse) (ZFP36) Antibodies

mRNA-binding protein involved in post-transcriptional regulation of AU-rich element (ARE)-containing mRNAs. Additionally we are shipping ZFP36 Kits (6) and ZFP36 Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ZFP36 67150 Q99MB7
ZFP36 7538 P26651
ZFP36 79426 P47973
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Top anti-ZFP36 Antibodies at antibodies-online.com

Showing 10 out of 75 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated IHC, WB IHC Information: Paraffin embedded small intestine, submucosal plexus tissue, tested with an antibody dilution of 5 ug/ml. 100 μL Log in to see 2 to 3 Days
$289.00
Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-ZFP36 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC, WB WB Suggested Anti-ZFP36 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: PANC1 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB Western blot analysis of ZFP36 Antibody (Center) (ABIN652899) in WiDr cell line lysates (35 µg/lane). ZFP36 (arrow) was detected using the purified polyclonal antibody. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of ZFP36 Antibody (Center) (ABIN652459) in mouse stomach tissue lysates (35 µg/lane).ZFP36 (arrow) was detected using the purified polyclonal antibody.(8 µg/mL) Formalin-fixed and paraffin-embedded human brain tissue reacted with ZFP36 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), WB Human Kidney (formalin-fixed, paraffin-embedded) stained with ZFP36 antibody ABIN214153 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 8 to 10 Days
$676.50
Details
Human Mouse Un-conjugated FACS, IF, WB HEK293T cells transfected with either RC202049 overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-ZFP36 antibody (ABIN2454211), and then analyzed by flow cytometry. Anti-ZFP36 mouse monoclonal antibody (ABIN2454211) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ZFP36 (RC202049). 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated FACS, IHC, WB Immunohistochemical staining of paraffin-embedded Human breast tissue using anti-ZFP36 mouse monoclonal antibody. (ABIN2454210) HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ZFP36 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-ZFP36. 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated WB HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ZFP36 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-ZFP36. 100 μL Log in to see 2 to 3 Days
$423.50
Details

ZFP36 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine)


Human , , ,
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Rat (Rattus)


Top referenced anti-ZFP36 Antibodies

  1. Chicken Polyclonal ZFP36 Primary Antibody for WB - ABIN2775764 : Esclatine, Taddeo, Roizman: Herpes simplex virus 1 induces cytoplasmic accumulation of TIA-1/TIAR and both synthesis and cytoplasmic accumulation of tristetraprolin, two cellular proteins that bind and destabilize AU-rich RNAs. in Journal of virology 2004 (PubMed)
    Show all 3 references for ABIN2775764

  2. Human Polyclonal ZFP36 Primary Antibody for FACS, IHC (p) - ABIN652459 : Strausberg, Feingold, Grouse, Derge, Klausner, Collins, Wagner, Shenmen, Schuler, Altschul, Zeeberg, Buetow, Schaefer, Bhat, Hopkins, Jordan, Moore, Max, Wang, Hsieh, Diatchenko, Marusina, Farmer et al.: Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. ... in Proceedings of the National Academy of Sciences of the United States of America 2002 (PubMed)

  3. Human Polyclonal ZFP36 Primary Antibody for WB - ABIN2780504 : Cao, Deterding, Venable, Kennington, Yates, Tomer, Blackshear: Identification of the anti-inflammatory protein tristetraprolin as a hyperphosphorylated protein by mass spectrometry and site-directed mutagenesis. in The Biochemical journal 2006 (PubMed)

  4. Human Polyclonal ZFP36 Primary Antibody for WB - ABIN652899 : Datta, Novotny, Pavicic, Zhao, Herjan, Hartupee, Hamilton: IL-17 regulates CXCL1 mRNA stability via an AUUUA/tristetraprolin-independent sequence. in Journal of immunology (Baltimore, Md. : 1950) 2010 (PubMed)

  5. Human Polyclonal ZFP36 Primary Antibody for IHC, WB - ABIN2775765 : Emmons, Townley-Tilson, Deleault, Skinner, Gross, Whitfield, Brooks: Identification of TTP mRNA targets in human dendritic cells reveals TTP as a critical regulator of dendritic cell maturation. in RNA (New York, N.Y.) 2008 (PubMed)

More Antibodies against ZFP36 Interaction Partners

Mouse (Murine) Zinc Finger Protein 36, C3H Type, Homolog (Mouse) (ZFP36) interaction partners

  1. Zinc Finger Protein 36 (show ZKSCAN1 Antibodies) deficiency has profound effects on the splenic transcriptome.

  2. Mouse LARP4 is regul (show LARP4 Antibodies)ated by TNF-alpha in a TT (show TNF Antibodies)P-dependent manner.

  3. Regulation of mRNAs by tristetraprolin appears to function as one of several critical post-transcriptional regulatory mechanisms controlling satellite cell homeostasis.

  4. Tristetraprolin limits inflammatory cytokine production in tumor-associated macrophages in an mRNA decay-independent manner.

  5. Dominant suppression of inflammation can be achieved via targeted mutation of the mRNA destabilizing protein tristetraprolin.

  6. DUSP1 (show DUSP1 Antibodies) and tristetraprolin cooperate to regulate macrophage responses to lipopolysaccharide.

  7. data shows TTP not only regulates the primary cellular response to innate immune stimuli, exemplified by TNF (show TNF Antibodies) elaborated from macrophages, but also regulates expression of transcripts involved in the secondary response of mesenchymal cells to TNF (show TNF Antibodies) stimulation

  8. study provides a novel mechanism for the posttranscriptional regulation of TF expression, indicating that this is selectively regulated by PARP-14 (show PARP14 Antibodies).

  9. Systemic inflammation caused by TTP deficiency leads to endothelial dysfunction; this process is independent of cholesterol and not mediated by TNF-alpha (show TNF Antibodies) solely.

  10. Intermedin (show ADM2 Antibodies) attenuates macrophage foam-cell formation via tristetraprolin-mediated degradation of CD36 (show CD36 Antibodies) mRNA.

Human Zinc Finger Protein 36, C3H Type, Homolog (Mouse) (ZFP36) interaction partners

  1. The mRNA destabilizing activity of TTP (show ADAMTS13 Antibodies) was increased when the partially disordered RNA binding domain (RBD (show CACNA1D Antibodies)) of TTP (show ADAMTS13 Antibodies) was replaced with the fully structured RBD (show CACNA1D Antibodies) of TIS11d (show ZFP36L2 Antibodies), indicating that differences in the folded state of the RBD (show CACNA1D Antibodies) affect the activity of the proteins in the cell.

  2. Tristetraprolin induces cell cycle arrest in breast tumor cells by targeting AP-1/c-Jun (show JUN Antibodies) and NF-kappaB (show NFKB1 Antibodies)/RelA (show NFkBP65 Antibodies) pathway.

  3. TTP (show ADAMTS13 Antibodies)-dependent regulatory pathway described herein likely contributes to the role of IL-22 (show IL22 Antibodies) in inflammation and cancer and may evolve as novel target for pharmacological IL-22 (show IL22 Antibodies) modulation.

  4. Results suggest that miR (show MLXIP Antibodies)-29a acts as an oncogene (show RAB1A Antibodies) by down regulating TTP (show ADAMTS13 Antibodies) and suggest the potential of miR (show MLXIP Antibodies)-29a and TTP (show ADAMTS13 Antibodies) as biomarkers.

  5. TTP (show ADAMTS13 Antibodies) might regulate interleukin (IL)-6 (show IL6 Antibodies) and IL-18 (show IL18 Antibodies) expression in diabetes. Diabetes with clinical proteinuria is accompanied by decreased urinary and serum level of TTP (show ADAMTS13 Antibodies) mRNA and protein, and increased levels of IL-6 (show IL6 Antibodies) and IL-18 (show IL18 Antibodies) mRNA and protein.

  6. Involvement of LARP4 (show LARP4 Antibodies) as a target of TNF-alpha (show TNF Antibodies)-TTP regulation provides a clue as to how its functional activity may be used in a physiologic pathway.

  7. Modulation of TAFI (show CPB2 Antibodies) levels by pro-inflammatory mediators or lipopolysaccharide involves binding of tristetraprolin to the CPB2 (show CPB2 Antibodies) 3'-UTR (show UTS2R Antibodies), which mediates CPB2 (show CPB2 Antibodies) mRNA destabilisation.

  8. DUSP1 (show DUSP1 Antibodies) overexpression and inhibition of MAPKs prevented IL1B (show IL1B Antibodies)-induced expression of ZFP36, this was associated with increased TNF (show TNF Antibodies) mRNA expression at 6 h, an effect that was predominantly due to elevated transcription.

  9. ZFP36 preferentially binds to 3' UTRs of mRNAs encoding regulators of gene expression.

  10. the biphasic nature of TNF-alpha (show TNF Antibodies)-induced IL-6 (show IL6 Antibodies) mRNA expression was regulated temporally by the RNA-destabilizing molecule, TTP (show ADAMTS13 Antibodies).

Pig (Porcine) Zinc Finger Protein 36, C3H Type, Homolog (Mouse) (ZFP36) interaction partners

  1. direct interaction between TTP protein and porcine TNF-alpha (show TNF Antibodies) mRNA ARE probe

ZFP36 Antigen Profile

Protein Summary

mRNA-binding protein involved in post-transcriptional regulation of AU-rich element (ARE)-containing mRNAs. Acts by specifically binding ARE-containing mRNAs and promoting their degradation. Plays a key role in the post-transcriptional regulation of tumor necrosis factor (TNF).

Gene names and symbols associated with ZFP36

  • tristetraproline (EDI_287240) antibody
  • Tristetraproline (Bm1_42085) antibody
  • tristetraproline (LOAG_03119) antibody
  • similar to Tristetraproline (TTP) (Zinc finger protein 36 homolog) (Zfp-36) (TIS11A protein) (TIS11) (Growth (ZFP36) antibody
  • zinc finger protein 36, C3H type, homolog (mouse) (ZFP36) antibody
  • ZFP36 ring finger protein (zfp36) antibody
  • ring finger protein 141 (Rnf141) antibody
  • ZFP36 ring finger protein (ZFP36) antibody
  • zinc finger protein 36 (Zfp36) antibody
  • 2610110L04Rik antibody
  • AA792898 antibody
  • AU022812 antibody
  • c3h-1 antibody
  • G0S24 antibody
  • Gos24 antibody
  • Nup475 antibody
  • RNF162A antibody
  • Tis11 antibody
  • TIS11D antibody
  • TISII antibody
  • Ttp antibody
  • Zfp-36 antibody
  • ZFP36 antibody
  • ZNF230 antibody

Protein level used designations for ZFP36

tristetraproline , Tristetraproline , similar to Tristetraproline (TTP) (Zinc finger protein 36 homolog) (Zfp-36) (TIS11A protein) (TIS11) (Growth , zinc finger protein 36, C3H type, homolog (mouse) , tristetraprolin , zinc finger protein 36, C3H type, homolog , RING finger protein 141 , zinc finger protein 230 , CCCH zinc finger protein C3H-1 , G0/G1 switch regulatory protein 24 , growth factor-inducible nuclear protein NUP475 , zinc finger protein 36 homolog , zinc finger protein, C3H type, 36 homolog , TTP , zfp-36 , TPA-induced sequence 11 , CCCH (CX8CX5CX3H) zinc finger domain RNA-binding protein , TIS11 , zinc finger protein homologous to Zfp-36 in mouse , TNF alpha inhibitor , Tax interacting protein

GENE ID SPECIES
5879635 Entamoeba dispar SAW760
6103302 Brugia malayi
9940506 Loa loa
698280 Macaca mulatta
736203 Pan troglodytes
100127733 Xenopus (Silurana) tropicalis
67150 Mus musculus
398102 Xenopus laevis
7538 Homo sapiens
79426 Rattus norvegicus
22695 Mus musculus
484510 Canis lupus familiaris
100316849 Sus scrofa
282127 Bos taurus
443283 Ovis aries
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