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ZNF382 encodes a KRAB domain zinc finger transcription factor (KZNF). Additionally we are shipping ZNF382 Antibodies (4) and many more products for this protein.
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Methylation changes of GFRA1 (show GFRA1 Proteins), SRF, and ZNF382 may be a potential biomarker set for prediction of gastric carcinoma metastasis.
Data suggests that zinc finger protein 382 (ZNF382) may be considered a putative tumor suppressor gene in pediatric acute myeloid leukemia (show BCL11A Proteins) (AML (show RUNX1 Proteins)).
Expression of MAGE (show MAGEB10 Proteins) I proteins, MAGE-A3 (show MAGEA3 Proteins) or MAGE-C2 (show MAGEC2 Proteins), relieved repression of a reporter gene by ZNF382 and MAGE (show MAGEB10 Proteins) I expression relieved KAP1 (show CDKN3 Proteins) mediated ID1 (show ID1 Proteins) repression.
ZNF382 is a functional tumor suppressor frequently methylated in multiple carcinomas.
mapped to chromosome 19q13.13; transcript specific for ZNF382 is expressed at very early embryonic stage; at the adult stage, ZNF382 expression is restricted largely to heart tissue
This gene encodes a KRAB domain zinc finger transcription factor (KZNF). KZNFs play critical roles in the regulation of many cellular processes including differentiation, proliferation and apoptosis. The encoded protein inhibits activating protein 1 (AP-1) and nuclear factor kappa-B (NF-kB) signaling and may function as a tumor suppressor in multiple carcinomas. This gene is found in a cluster with other zinc finger protein genes on the long arm of chromosome 19, and alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
zinc finger protein 382
, KRAB/zinc finger suppressor protein 1
, multiple zinc finger and krueppel-associated box protein KS1
, KRAB/zinc finger suppressor protein 1 (KS1)