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Zinc Finger Protein 384 (ZNF384) ELISA Kits

ZNF384 encodes a C2H2-type zinc finger protein, which may function as a transcription factor. Additionally we are shipping Zinc Finger Protein 384 Antibodies (54) and Zinc Finger Protein 384 Proteins (4) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human ZNF384 ZNF384 171017 Q8TF68
Anti-Mouse ZNF384 ZNF384 269800  
Anti-Rat ZNF384 ZNF384 171018 Q9EQJ4
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More ELISA Kits for Zinc Finger Protein 384 Interaction Partners

Human Zinc Finger Protein 384 (ZNF384) interaction partners

  1. Rare translocation t(12;17)(p13;q12), This translocation has been reported in 25 cases and its putative molecular consequence, the formation of a TAF15-ZNF384 fusion gene, in only six cases.

  2. The transcription factor gene CIZ/NMP4 is recurrently involved in acute leukemia through fusion with either EWSR1 (show EWSR1 ELISA Kits) or TAF15.

  3. The CIZ protein(also known as ZNF384)was involved and rearrangemented in acute leukemia.

  4. These results suggest that caspase (show CASP3 ELISA Kits)-mediated degradation may represent a novel regulatory mechanism that controls TAF15 and TAF15-CIZ/NMP4 activities.

Mouse (Murine) Zinc Finger Protein 384 (ZNF384) interaction partners

  1. NMP4 deficiency suppressed the arthritis-induced increase in bone resorption, expression of RANKL (show TNFSF11 ELISA Kits) and MMP-3 (show MMP3 ELISA Kits) mRNA.

  2. Nmp4/CIZ limits the parathyroid hormone (show PTH ELISA Kits) anabolic window by restricting the number of bone marrow stem, progenitor, and blood cells that support anabolic bone remodeling.

  3. The CIZ/NMP4 expression levels are correlated to the metastatic activity in divergent types of melanoma cells.

  4. Together these results provide experimental support for the concept that Nmp4/CIZ plays an inhibitory role in the response of bone cells to mechanical stimulation induced by OFSS.

  5. Nmp4/CIZ within the context of the PTH (show PTH ELISA Kits)-induced anabolic response is described.

  6. Impaired spermatogenesis and male infertility occurred in Nmp4-disrupted mice.

  7. transformation of 3T3 fibroblasts by CIZ/NMP4 fusions is dependent on DNA-binding and might involve transactivation of CIZ target genes

  8. Two adjacent promoters of Nmp4 P(1) [-2521 nucleotide (nt)/-597 nt] and P(2) (-2521 nt/+1 nt) initiate transcription of alternative first exons (U(1) and U(2)).

  9. Histomorphometric analysis revealed that unloading suppressed the levels of osteoblastic bone formation parameters, and such suppression of bone formation parameters was blocked by CIZ-deficiency.

  10. Nmp4 contributes to fluid shear stress induced MMP13 (show MMP13 ELISA Kits) gene induction in osteoblasts.

Zinc Finger Protein 384 (ZNF384) Antigen Profile

Antigen Summary

This gene encodes a C2H2-type zinc finger protein, which may function as a transcription factor. This gene also contains long CAG trinucleotide repeats that encode consecutive glutamine residues. The protein appears to bind and regulate the promoters of the extracellular matrix genes MMP1, MMP3, MMP7 and COL1A1. Studies in mouse suggest that nuclear matrix transcription factors (NP/NMP4) may be part of a general mechanical pathway that couples cell construction and function during extracellular matrix remodeling. Alternative splicing results in multiple transcript variants. Recurrent rearrangements of this gene with the Ewing's sarcoma gene, EWSR1 on chromosome 22, or with the TAF15 gene on chromosome 17, or with the TCF3 (E2A) gene on chromosome 19, have been observed in acute leukemia. A related pseudogene has been identified on chromosome 7.

Gene names and symbols associated with ZNF384

  • zinc finger protein 384 (ZNF384) antibody
  • zinc finger protein 384 (Zfp384) antibody
  • zinc finger protein 384 (znf384) antibody
  • BB163993 antibody
  • C130073D16Rik antibody
  • CAGH1 antibody
  • CAGH1A antibody
  • Ciz antibody
  • ERDA2 antibody
  • Nmp4 antibody
  • NP antibody
  • TNRC1 antibody
  • Znf384 antibody

Protein level used designations for ZNF384

CAG repeat protein 1 , Cas-interacting zinc finger protein , expanded repeat domain, CAG/CTG 2 , nuclear matrix transcription factor 4 , trinucleotide repeat-containing gene 1 protein , nuclear matrix protein 4 , Cas-associated zinc finger protein

GENE ID SPECIES
171017 Homo sapiens
269800 Mus musculus
171018 Rattus norvegicus
446592 Xenopus laevis
515007 Bos taurus
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