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The protein encoded by 104125 is a nuclear protein that belongs to the family of Kruppel-like C2H2 zinc finger proteins. Additionally we are shipping Zinc Finger Protein 423 Antibodies (15) and and many more products for this protein.
two multi-zinc finger transcription cofactors named ZNF423 and ZNF521 have been characterised as potent inhibitors of EBF1 (show EBF1 ELISA Kits) and are emerging as potentially relevant contributors to the development of B-cell leukaemias
ZNF423 expression is associated with poor outcome of ETV6 (show ETV6 ELISA Kits)-RUNX1 (show RUNX1 ELISA Kits)-negative B precursor acute lymphoblastic leukemia patients.
OAZ (show OAZ1 ELISA Kits) gene expression was highly enriched in mesenchymal stem cells (MSCs) compared with peripheral blood leukocytes and was increased in patients with systemic lupus erythematosus (SLE) compared with control subjects.
These findings suggest that expression of UBR5 (show UBR5 ELISA Kits)-ZNF423 protein might contribute to the transformation of a subset of Nasopharyngeal carcinoma
Study identifies by whole-exome resequencing, mutations of MRE11 (show MRE11A ELISA Kits), ZNF423, and CEP164 (show CEP164 ELISA Kits) as causing Nephronophthisis-related ciliopathies.
Elevated expression of OAZ (show OAZ1 ELISA Kits) transcripts in systemic lupus erythematosus PBLs were strongly correlated with disease activity.
The expression level of OAZ (show OAZ1 ELISA Kits) mRNA in the bone marrow and peripheral blood of SLE patients was significantly increased than those observed in normal controls.
Low ZNF423 expression is associated with neuroblastoma (show ARHGEF16 ELISA Kits).
ZFP423 coordinates Notch1 (show NOTCH1 ELISA Kits) and bone morphogenetic protein signaling, selectively up-regulating Hes5 (show HES5 ELISA Kits) gene expression.
Zfp423 is a critical regulator of adipogenesis in stromal vascular cells of bovine muscle.
loss of Zfp423 alters expression of several genes encoding key cilium components, including increased expression of Tulp3. Tulp3 is a direct binding target of Zfp423 and reducing the overexpression of Tulp3 in Zfp423-deficient cells suppresses Smoothened translocation defects.
Data show that the expression of miR (show MLXIP ELISA Kits)-195a is regulated during adipocyte differentiation and identified Zfp423 as its novel target.
the antiadipogenic function of Zfp521 is mostly exerted through repression of Zfp423 and the downstream target PPAR-gamma (show PPARG ELISA Kits) gene.
Zfp423 binds autoregulatory sites in a developmental cell culture model.
Maternal obesity enhanced Zfp423 expression and adipogenic differentiation during fetal development, at least partially through reducing DNA methylation (show HELLS ELISA Kits) in the Zfp423 promoter.
Constitutive expression of a C-terminal mutant OAZ (show OAZ1 ELISA Kits) that selectively disrupts OAZ (show OAZ1 ELISA Kits)-O/E interaction while retaining other activities, exhibits apparently normal OSN (show SPARC ELISA Kits) differentiation.
Zfp423 expression identifies committed preadipocytes and localizes to adipose endothelial and perivascular cells.
Zfp423(-/-) hemisphere malformations are shaped by both genetic and non-genetic factors to produce distinct phenotypes.
Zfp423 as a transcriptional regulator of preadipocyte determination
The protein encoded by this gene is a nuclear protein that belongs to the family of Kruppel-like C2H2 zinc finger proteins. It functions as a DNA-binding transcription factor by using distinct zinc fingers in different signaling pathways. Thus, it is thought that this gene may have multiple roles in signal transduction during development. Mutations in this gene are associated with nephronophthisis-14 and Joubert syndrome-19. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
OLF-1/EBF associated zinc finger
, Smad- and Olf-interacting zinc finger protein
, early B-cell factor associated zinc finger protein
, olf1/EBF-associated zinc finger protein
, early B-cell factor associated zinc finger transcription factor
, early B-cell factor-associated zinc finger protein
, smad- and Olf-interacting zinc finger protein
, zinc finger protein 104
, Olf-1/EBF associated Zn finger protein Roaz