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Zinc-finger proteins bind nucleic acids and play important roles in various cellular functions, including cell proliferation, differentiation, and apoptosis. Additionally we are shipping and many more products for this protein.
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one interacting gene pair (RBMS3 (show RBMS3 Antibodies) versus ZNF516) which, even after Bonferroni correction for multiple testing, showed consistently significant effects on hip bone mineral density.
ZNF516 promoter methylation was the best biomarker, with both sensitivity and specificity of 90% (AUC = 0.92), results subsequently corroborated in a Prevalence cohort.
Zfp516 directly binds to the proximal region of the UCP1 (show UCP1 Antibodies) promoter, not to the enhancer region where other transcription factors bind, and interacts with PRDM16 (show PRDM16 Antibodies) to activate the UCP1 (show UCP1 Antibodies) promoter.
Zinc-finger proteins bind nucleic acids and play important roles in various cellular functions, including cell proliferation, differentiation, and apoptosis. This gene encodes a zinc-finger protein, and belongs to the krueppel C2H2-type zinc-finger protein family. It may be involved in transcriptional regulation.