anti-Zinc Finger Protein 521 (ZNF521) Antibodies

Transcription factor that can both act as an activator or a repressor depending on the context. Additionally we are shipping and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ZNF521 307579  
ZNF521 25925 Q96K83
ZNF521 225207 Q6KAS7
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Top anti-Zinc Finger Protein 521 Antibodies at antibodies-online.com

Showing 10 out of 50 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, IF, WB   0.1 mg Log in to see 12 to 15 Days
$375.38
Details
Human Rabbit Un-conjugated EIA, IHC (p)   0.1 mg Log in to see 12 to 15 Days
$375.38
Details
Human Rabbit Un-conjugated ICC, ELISA, WB 100 μg Log in to see 2 to 3 Days
$420.00
Details
Human Rabbit Un-conjugated IHC (p), WB Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 7 to 9 Days
$451.00
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p)   0.1 mL Log in to see 10 to 13 Days
$439.69
Details
Human Rabbit Un-conjugated IHC (p) Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 7 to 9 Days
$451.00
Details
Human Rabbit Un-conjugated IHC, ELISA 0.1 mg Log in to see 2 to 3 Days
$340.00
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of ZNF521 in HeLa cell lysate with ZNF521 antibody at 1 µg/mL in (A) the absence and (B) the presence of blocking peptide. 0.1 mg Log in to see 2 to 3 Days
$340.00
Details
Human Rabbit Un-conjugated ELISA, ICC, IF, WB   0.1 mg Log in to see 8 to 11 Days
$447.56
Details
Mouse Rabbit Un-conjugated EIA, IHC (fro), IF, WB   0.2 mL Log in to see 6 to 8 Days
$533.50
Details

ZNF521 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Rat (Rattus)


Human , , ,


, , , , , , , , , ,
Mouse (Murine) , ,


, , , , , , , , , ,

Top referenced anti-Zinc Finger Protein 521 Antibodies

  1. Human Polyclonal ZNF521 Primary Antibody for ICC, IF - ABIN4367327 : Spina, Filocamo, Iaccino, Scicchitano, Lupia, Chiarella, Mega, Bernaudo, Pelaggi, Mesuraca, Pazzaglia, Semenkow, Bar, Kool, Pfister, Bond, Eberhart, Steinkühler, Morrone: Critical role of zinc finger protein 521 in the control of growth, clonogenicity and tumorigenic potential of medulloblastoma cells. in Oncotarget 2013 (PubMed)

More Antibodies against Zinc Finger Protein 521 Interaction Partners

Human Zinc Finger Protein 521 (ZNF521) interaction partners

  1. knockdown of ZNF521 reduced proliferation in human leukemia cell li (show FUT1 Antibodies)nes possessing MLL-AF9 transloca (show MLL Antibodies)tion (show MLLT3 Antibodies)s

  2. two multi-zinc finger transcription cofactors named ZNF423 (show 104125 Antibodies) and ZNF521 have been characterised as potent inhibitors of EBF1 (show EBF1 Antibodies) and are emerging as potentially relevant contributors to the development of B-cell leukaemias

  3. Data show that zinc finger protein 521 (ZNF521) can function as a repressor of osteoblastic differentiation of bone marrow mesenchymal stem cells (bmMSCs).

  4. Newly discovered ZNF521-molecular partners of potentially relevant functional role, such as ZNF423 (show 104125 Antibodies), Spt16 (show SUPT16H Antibodies), Spt5 (show SUPT5H Antibodies), were discovered and validated by Western blotting.

  5. Data strongly support the notion that ZNF521, through the recruitment of the NuRD complex, contributes to the clonogenic growth, migration and tumorigenicity of medulloblastoma cells.

  6. Data show that ZNF521 can antagonize B-cell development and support the notion that it may contribute to conserve the multipotency of primitive lympho-myeloid progenitors by preventing or delaying their EBF1 (show EBF1 Antibodies)-driven commitment toward the B-cell lineage.

  7. Zinc finger protein 521, a new player in bone formation.

  8. EHZF is likely to play a relevant role in the control of human hematopoiesis and might be implicated in the development of hematopoietic malignancies.

  9. A review of possible roles for ZNF521 in development, stem cell regulation and oncogenesis.

  10. ZNF521 modulates erythroid cell differentiation through direct binding with GATA-1 (show GATA1 Antibodies).

Mouse (Murine) Zinc Finger Protein 521 (ZNF521) interaction partners

  1. these results identify ZNF521/ZFP521 as a critical regulator of HSC (show FUT1 Antibodies) function, which facilitates MLL (show MLL Antibodies)-AF9 (show MLLT3 Antibodies)-mediated leukemic disease in mice.

  2. links between dysregulated Zfp521 and B-cell survival

  3. Here we demonstrate that the transcription factors SPI1 (show SPI1 Antibodies) (PU.1) and HOXC13 synergistically regulate Zfp521 expression, and identify the regions of the Zfp521 promoter required for this transcriptional activity. We also show that SPI1 (show SPI1 Antibodies) and HOXC13 activate Zfp521 in a dose-dependent manner.

  4. Data suggest a facilitated approach for establishing human neural stem cells (NSCs) through zinc finger protein 521 (Zfp521)-driven conversion of fibroblasts.

  5. it is concluding that an enhanced expression of Fndc5 (show FNDC5 Antibodies) in neural progenitor cells is stimulated by Zfp521 overexpression in these cells

  6. Data show that zinc finger protein 521 (ZNF521) overexpression repressed osteoblastic differentiation of C3H10T1/2 cells.

  7. Runx1 (show RUNX1 Antibodies)-dependent transcription factor gene Zfp521 is expressed in, and required for establishing molecular features that define, mechanoreceptors.

  8. the data suggest that Zfp521 is a cell fate switch critical for BMP-induced osteoblast commitment and identify Zfp521 as the intrinsic repressor of Zfp423 and hence of adipocyte commitment during BMP-induced mesenchymal precursor differentiation.

  9. the interplay between Zfp521 and Ebf1 (show EBF1 Antibodies) is identified as a novel rheostat for bone homeostasis.

  10. Reduction of Zfp521 enhances adipogenic potential in vivo.

Zinc Finger Protein 521 (ZNF521) Antigen Profile

Protein Summary

Transcription factor that can both act as an activator or a repressor depending on the context. Involved in BMP signaling and in the regulation of the immature compartment of the hematopoietic system. Associates with SMADs in response to BMP2 leading to activate transcription of BMP target genes. Acts as a transcriptional repressor via its interaction with EBF1, a transcription factor involved specification of B-cell lineage\; this interaction preventing EBF1 to bind DNA and activate target genes.

Gene names and symbols associated with ZNF521

  • zinc finger protein 521 (Zfp521) antibody
  • zinc finger protein 521 (ZNF521) antibody
  • zinc finger protein 521 (znf521) antibody
  • B930086A16Rik antibody
  • EHZF antibody
  • Evi3 antibody
  • Znf521 antibody

Protein level used designations for ZNF521

LYST-interacting protein 3 , early hematopoietic zinc finger protein , ecotropic viral integration site 3 protein

GENE ID SPECIES
307579 Rattus norvegicus
421083 Gallus gallus
490511 Canis lupus familiaris
538792 Bos taurus
25925 Homo sapiens
225207 Mus musculus
414550 Xenopus laevis
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