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The protein encoded by ZFP57 is a zinc finger protein containing a KRAB domain. Additionally we are shipping ZFP57 Antibodies (27) and many more products for this protein.
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transient neonatal diabetes type 1 is associated with ZFP57 mutations
ZFP57 regulates the expression of insulin-like growth factor 2 (IGF2 (show IGF2 Proteins)), which has a critical role in ZFP57-induced anchorage-independent growth
High grade glioblastoma is associated with increased level of ZFP57, a protein involved in gene imprinting, and aberrant expression of CPT1A (show CPT1A Proteins) and CPT1C (show CPT1C Proteins).
These data identify ZFP57 as a candidate gene underlying reported MHC disease associations, notably for putative regulatory variants associated with cancer and HIV-1.
Mouse and human ZFP57 are orthologs despite relatively low sequence identity.
ZFP57 vZFP57 vZFP57
no evidence for ZFP57 alterations as a major cause in sporadic Beckwith-Wiedemann Syndrome cases
this study does not provide evidence that ZFP57 mutations are the cause of 11p15-hypomethylation in Silver-Russell syndrome (SRS (show SMS Proteins)) patients and contribute to the aetiology of SRS (show SMS Proteins)
Study reports mutations in ZFP57, which encodes a zinc-finger transcription factor (show OSR1 Proteins) expressed in early development, in seven pedigrees with a shared pattern of mosaic hypomethylation and a conserved range of clinical features.
The protein encoded by this gene is a zinc finger protein containing a KRAB domain. Studies in mouse suggest that this protein may function as a transcriptional repressor. Mutations in this gene have been associated with transient neonatal diabetes mellitus type 1 (TNDM1).
, zinc finger protein 57 homolog
, zinc finger protein 698