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Transcription repressor that specifically binds to the 5'-TATTTT[T/G]-3' consensus sequence on promoters and repress transcription of PGC-1-alpha (PPARGC1A), thereby playing a role in regulation of neuron death (By similarity). Additionally we are shipping ZNF746 Antibodies (7) and and many more products for this protein.
Taken together, these results suggest that PARIS and PIASy (show PIAS4 ELISA Kits) modulate PGC (show PGC ELISA Kits)-1a gene transcription through distinct molecular mechanisms.
these findings suggest that inhibition of ZNF746 suppresses the invasion and epithelial to mesenchymal transition molecules in H460 NSCLC cells and ZNF746 may be an important target molecule in lung tumorigenesis.
PARIS(ZNF746) is a KRAB and zi (show PARK2 ELISA Kits)nc finger protein that accumulates in models of parkin inactivation and in human PD brain.
Conditional knockout of parkin (show PARK2 ELISA Kits) in adult animals leads to progressive loss of dopamine neurons in a PARIS-dependent manner.
Transcription repressor that specifically binds to the 5'-TATTTT-3' consensus sequence on promoters and repress transcription of PGC-1-alpha (PPARGC1A), thereby playing a role in regulation of neuron death (By similarity).
zinc finger protein 746
, parkin-interacting substrate
, parkin-interacting sustrate