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Zinc Finger and AT Hook Domain Containing (ZFAT) ELISA Kits

ZFAT encodes a protein that likely binds DNA and functions as a transcriptional regulator involved in apoptosis and cell survival. Additionally we are shipping ZFAT Antibodies (3) and and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human ZFAT ZFAT 57623 Q9P243
Anti-Mouse ZFAT ZFAT 380993 Q7TS63
Anti-Rat ZFAT ZFAT 362925  
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More ELISA Kits for ZFAT Interaction Partners

Human Zinc Finger and AT Hook Domain Containing (ZFAT) interaction partners

  1. We describe the structural features of the ZFAT ZFs, including the structural differences on the putative DNA recognition surfaces among the ZFAT ZFs, and the unique interaction mode within the tandem ZFs of ZF4 and ZF5 (show ZFP161 ELISA Kits)

  2. ZFAT is paternally expressed in the placenta (as ZFAT-AS1, a non-coding antisense RNA)but biallelic in other tissues.

  3. ZFAT polymorphism was associated with the Hashimoto disease severity but not with its development.

  4. These results suggest that ZFAT may have critical roles in the capillary-like network formation that is involved in vascular remodeling.

  5. It plays a specific role in differentiation and immunologic stimulation in B and T cells to cause autoimmune thyroid disease and contains AT-hook domain and 18 C2H2-type zin finger domain.

  6. Polymorphism, Single Nucleotide in ZFAT is associated with autoimmune thyroid disease

  7. ZFAT protein is a critical regulator involved in apoptosis and cell survival for immune-related cells

Mouse (Murine) Zinc Finger and AT Hook Domain Containing (ZFAT) interaction partners

  1. results demonstrate that Zfat critically participates in the development of DP thymocytes through regulating the activities of p38 (show CRK ELISA Kits) and JNK (show MAPK8 ELISA Kits).

  2. Zfat is required for peripheral T-cell homeostasis through IL-7Ralpha (show IL7R ELISA Kits) expression by controlling the FoxO1 (show FOXO1 ELISA Kits) protein.

  3. Zfat-deficiency results in a loss of CD3zeta (show CD247 ELISA Kits) phosphorylation with dysregulation of ERK (show EPHB2 ELISA Kits) and Egr (show EGR1 ELISA Kits) activities leading to impaired positive selection.

  4. ZFAT is a critical molecule for cell survival in MEFs and MOLT-4 cells at least in part through the regulation of the apoptosis involved in the BCL-2 (show BCL2 ELISA Kits)- and IL6st (show IL6ST ELISA Kits)-mediated pathways.

  5. ZFAT is indispensable for mouse embryonic development and functions as a critical transcription factor for primitive hematopoiesis through direct-regulation of Tal1 (show TAL1 ELISA Kits), Lmo2 (show LMO2 ELISA Kits), and Gata1 (show GATA1 ELISA Kits)

  6. Study shows that ZFAT protein is expressed in B and T lymphocytes in mouse and that ZFAT regulates immune-related genes functionally important for immune responsiveness.

ZFAT Antigen Profile

Antigen Summary

This gene encodes a protein that likely binds DNA and functions as a transcriptional regulator involved in apoptosis and cell survival. This gene resides in a susceptibility locus for autoimmune thyroid disease (AITD) on chromosome 8q24. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Gene names and symbols associated with ZFAT

  • zinc finger and AT hook domain containing (ZFAT) antibody
  • zinc finger and AT hook domain containing (zfat) antibody
  • zinc finger and AT hook domain containing (Zfat) antibody
  • AITD3 antibody
  • Gm922 antibody
  • Zfat1 antibody
  • Zfp406 antibody
  • ZNF406 antibody

Protein level used designations for ZFAT

zinc finger and AT hook domain containing , zinc finger protein 406-like , ZFAT-1-like , zinc finger protein ZFAT-like , zinc finger gene in autoimmune thyroid disease , zinc finger protein 406 , zinc finger protein ZFAT , zinc-finger gene in AITD susceptibility region , ZFAT zinc finger 1 , zinc finger protein 403

GENE ID SPECIES
522282 Bos taurus
566334 Danio rerio
698512 Macaca mulatta
100032644 Monodelphis domestica
100069060 Equus caballus
100394561 Callithrix jacchus
100440709 Pongo abelii
100463922 Ailuropoda melanoleuca
57623 Homo sapiens
482051 Canis lupus familiaris
380993 Mus musculus
362925 Rattus norvegicus
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