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Zinc Finger and BTB Domain Containing 16 Proteins (ZBTB16)

ZBTB16 is a member of the Krueppel C2H2-type zinc-finger protein family and encodes a zinc finger transcription factor that contains nine Kruppel-type zinc finger domains at the carboxyl terminus. Additionally we are shipping ZBTB16 Antibodies (69) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ZBTB16 7704 Q05516
Mouse ZBTB16 ZBTB16 235320  
Rat ZBTB16 ZBTB16 353227  
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Top ZBTB16 Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

ZBTB16 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,

More Proteins for Zinc Finger and BTB Domain Containing 16 (ZBTB16) Interaction Partners

Human Zinc Finger and BTB Domain Containing 16 (ZBTB16) interaction partners

  1. integration of PLZF ChIP-Seq and RNA Pol II RNA-Seq datasets revealed that the early growth response 1 (EGR1 (show EGR1 Proteins)) transcription factor is a PLZF target for which its level of expression must be reduced to enable progesterone dependent hESC decidualization

  2. NLRP7 is involved in Hydatidiform Molar Pregnancy (HYDM1) and interacts with the transcriptional repressor ZBTB16

  3. These results support a prognostic value for loss of cytoplasmic PLZF expression in the stratification of non-small cell lung cancer and a possible role of cytoplasmic shift and down-regulation of PLZF in the pathogenesis of NSCLC.

  4. down-regulation of PLZF is an important molecular process for prostate tumor progression

  5. Down-regulation of PLZF in human hepatocellular carcinoma.PLZF expression was positively correlated with the alkaline phosphatase level in hepatocellular carcinoma patients.

  6. In dental follicle cells, a Runx2 (show RUNX2 Proteins)-independent differentiation mechanism exists that is regulated by ZBTB16.

  7. PLZF loss enhances castration-resistant prostate cancer tumor growth in a xenograft model.

  8. Data suggest that interleukin-32alpha (IL-32alpha) associates with leukemia zinc finger (PLZF) and protein kinase c epsilon (show PRKCE Proteins) (PKCvarepsilon), and then inhibits PLZF sumoylation, resulting in suppression of the transcriptional activity of PLZF.

  9. PLZF regulates CCR6 (show CCR6 Proteins) and is critical for the acquisition and maintenance of the Th17 phenotype in human cells.

  10. Authors found that PLZF mediates suppression of miR (show MLXIP Proteins)-146a to control increases of CXCR4 (show CXCR4 Proteins) and TRAF6 (show TRAF6 Proteins) protein levels in human primary CD4 (show CD4 Proteins)(+) T lymphocytes.

Mouse (Murine) Zinc Finger and BTB Domain Containing 16 (ZBTB16) interaction partners

  1. Results clearly indicate that PLZF promotes cell cycle exit and cell differentiation into hypertrophic chondrocytes.

  2. plzf has a role in regulating HSC (show FUT1 Proteins) function that is linked to cell cycle regulation

  3. PLZF expression is highly specific to innate T cells and cannot be induced in conventional T cells via TCR-mediated activation or inflammatory challenge

  4. PLZF expression at the innate lymphoid cell precursor stage has a long-range effect on the functional properties of mature ILC2s and highlights the importance of these cells for innate allergic responses in otherwise immunocompetent mice.

  5. Data suggest that age-related increase in Plzf expression represents a novel molecular signature of spermatogonia aging by functionally arresting their differentiation.

  6. Data indicate the function of promyelocytic leukaemia zinc finger PLZF in the development of innate-like interleukin-17 (show IL17A Proteins), TcR gamma-delta (IL-17 (show IL17A Proteins)+Vgamma6+ gammadelta) T cells.

  7. The data suggest that Pak2 (show PAK2 Proteins) controls thymic Natural Killer T-cell development by providing a signal that links Egr2 (show EGR2 Proteins) to induce PLZF, in part by regulating signaling lymphocyte activation molecule (show SLAMF1 Proteins) 6 expression.

  8. The acetyltransferase HAT1 (show HAT1 Proteins) moderates the NF-kappaB (show NFKB1 Proteins) inflammatory response by regulating the transcription factor PLZF.

  9. G-protein-coupled receptors, such as CXCR4, regulate autophagy by ZBTB16-mediated ubiquitination and proteasomal degradation of Atg14L .

  10. Data conclude that PLZF is a critical regulator of hepatic gluconeogenesis.

Zebrafish Zinc Finger and BTB Domain Containing 16 (ZBTB16) interaction partners

ZBTB16 Protein Profile

Protein Summary

This gene is a member of the Krueppel C2H2-type zinc-finger protein family and encodes a zinc finger transcription factor that contains nine Kruppel-type zinc finger domains at the carboxyl terminus. This protein is located in the nucleus, is involved in cell cycle progression, and interacts with a histone deacetylase. Specific instances of aberrant gene rearrangement at this locus have been associated with acute promyelocytic leukemia (APL). Alternate transcriptional splice variants have been characterized.

Gene names and symbols associated with ZBTB16

  • zinc finger and BTB domain containing 16 (ZBTB16)
  • zinc finger and BTB domain containing 16 (Zbtb16)
  • zinc finger and BTB domain containing 16a (zbtb16a)
  • AI467657 protein
  • lu protein
  • Lx protein
  • Plzf protein
  • wu:fb93g12 protein
  • wu:fc07c10 protein
  • zbtb16 protein
  • Zfp145 protein
  • zgc:55675 protein
  • Znf145 protein

Protein level used designations for ZBTB16

zinc finger and BTB domain-containing protein 16 , zinc finger protein 145 (Kruppel-like, expressed in promyelocytic leukemia) , zinc finger protein PLZF , promyelocytic leukemia zinc finger protein , Green's luxoid , luxoid , zinc finger protein 145 , Polydactyly-luxate syndrome , promyelocytic leukemia zinc finger , zinc finger and BTB domain containing 16 protein , plzfa , promyelocytic leukemia zinc finger protein-A , zinc finger and BTB domain containing 16 , zinc finger and BTB domain-containing protein 16-A , zinc finger protein PLZF-A

GENE ID SPECIES
7704 Homo sapiens
419759 Gallus gallus
534401 Bos taurus
235320 Mus musculus
353227 Rattus norvegicus
323269 Danio rerio
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