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DNA-binding protein that binds to the to a 5'- TGTACAGTGT-3' core sequence. Additionally we are shipping ZBTB32 Antibodies (47) and many more products for this protein.
Showing 4 out of 4 products:
confirmed that the promyelocytic leukemia zinc finger (PLZF (show ZBTB16 Proteins)) BTB dimer is strand exchanged in solution, while the FAZF BTB dimer is not
Here, it was shown that human endogenous retrovirus Rec can form a trimeric complex with TZFP and AR, and can relieve the TZFP-mediated repression of AR-induced transactivation.
can interact with GATA-2 (show GATA2 Proteins) and can modify GATA-2 (show GATA2 Proteins) transactivation capacity
results suggest an essential role for FAZF during the proliferative stages of primitive hematopoietic progenitors, possibly acting in concert with (a subset of) the Fanconi anemia (show PALB2 Proteins) proteins
TZFP is identified as a novel BMP2 (show BMP2 Proteins)-induced transcription factor during osteoblastic differentiation.
This study showed that DCIR2(+) DCs are capable of inducing antigen-specific tolerance in the face of ongoing autoimmunity; Zbtb32 is a suppressive transcription factor that controls T cell-mediated autoimmunity.
Zbtb32 acts as a cellular 'hub' through which proinflammatory signals instruct a 'proliferation-permissive' state in NK cells, thereby allowing their prolific expansion in response to viral infection.
that Tzfp function as a transcriptional regulator and that loss of the protein leads to alterations in AR signaling
The study reports a remarkable >1000-fold upregulation of individual piRNAs in pachytene spermatocytes isolated from Tzfp-deficient murine testes.
It is concluded that ROG can inhibit the expression of Th1 (show HAND1 Proteins) and Th2 cytokines by down-regulating the expression of ICOS (show ICOS Proteins), which might be a potential molecular target for asthma treatment.
Rog plays an inhibitory role in allergic inflammation.
ROG may confer CD8 (show CD8A Proteins) T cell-specific repression of histone hyperacetylation and activation of the IL-4 (show IL4 Proteins) gene locus.
ROG is a critical part of a transcription factor NF-ATc2 (show NFAT1 Proteins)-initiated negative feedback mechanism of T cell activation.
PLZP in mice has roles in T-lymphocyte proliferation, cytokine production, and hematopoietic stem cell homeostasis
Data show that ROG-deficient T cells are hypersensitive to anti-CD3 (show CD3E Proteins) stimulation and produce more interleukin-2 (IL-2 (show IL2 Proteins)) due to enhanced NF-kappaB (show NFKB1 Proteins) activity.
DNA-binding protein that binds to the to a 5'- TGTACAGTGT-3' core sequence. May function as a transcriptional transactivator and transcriptional repressor (By similarity). Probably exerts its repressor effect by preventing GATA3 from binding to DNA. May play a role in regulating the differentiation and activation of helper T-cells.
zinc finger and BTB domain-containing protein 32
, FANCC-interacting protein
, fanconi anemia zinc finger protein
, repressor of GATA
, testis zinc finger protein
, zinc finger protein 538
, GATA repressor