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Zinc Finger and BTB Domain Containing 7A Proteins (ZBTB7A)

acts as a transcriptional repressor\; may play a role in osteoclastogenesis [RGD, Feb 2006].. Additionally we are shipping ZBTB7A Antibodies (106) and ZBTB7A Kits (14) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ZBTB7A 51341 O95365
Mouse ZBTB7A ZBTB7A 16969 O88939
ZBTB7A 117107 Q9QZ48
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Top ZBTB7A Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,631.83
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

ZBTB7A Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Rat (Rattus)

More Proteins for Zinc Finger and BTB Domain Containing 7A (ZBTB7A) Interaction Partners

Human Zinc Finger and BTB Domain Containing 7A (ZBTB7A) interaction partners

  1. ZBTB7A directly binds to the promoter and transcriptionally represses the expression of MCAM (show MCAM Proteins), establishing ZBTB7A as a bona fide transcriptional repressor of MCAM (show MCAM Proteins)

  2. MEF2D (show MEF2D Proteins) was also found to increase the transcription of Pokemon by binding myocyte enhancer factor 2 (MEF2 (show MEF2A Proteins)) sites within its promoter region, that can promote Hepatocellular carcinoma invasion

  3. this study found that LRF/ZBTB7A transcription factor occupies fetal gamma-globin (show HBG1 Proteins) genes and maintains the nucleosome density necessary for gamma-globin (show HBG1 Proteins) gene silencing in adults, and that LRF confers its repressive activity through a NuRD repressor complex independent of the fetal globin repressor BCL11A (show BCL11A Proteins).

  4. p38beta (show MAPK11 Proteins) is a novel regulatory target of the transcription factor Pokemon and positively regulated by Pokemon in hepatic cells.

  5. Taken together, all these data suggest that Pokemon is a new partner of Smad4 (show SMAD4 Proteins) and plays a negative role in TGF-beta (show TGFB1 Proteins) pathway.

  6. Pokemon prevents anoikis through the suppression of Bim (show BCL2L11 Proteins) expression, which facilitates tumor cell invasion and metastasis.

  7. Pokemon enhanced the oncogenesis of colorectal cancer by promoting cell proliferation, cell cycle progression and anti-apoptosis activity.

  8. our findings suggest that TGF-b1 may inhibit the expression of Pokemon, b-catenin, and E-cadherin (show CDH1 Proteins). The high expression of TGF-b1 leads to an increase in the phenotype and apical-base polarity of epithelial cells

  9. a potential regulatory role of FBI-1 in transcription factor activity of ETS-1 (show ETS1 Proteins)

  10. Pokemon expression of NP69 and C666-1 obviously varied from mRNA to protein.

Mouse (Murine) Zinc Finger and BTB Domain Containing 7A (ZBTB7A) interaction partners

  1. This study demonstrated an unexpected transcription-independent function for LRF in the classical non-homologous end joining pathway of double-strand break repair.

  2. LRF short hairpin RNA suppressed the expression of LRF protein in a glioma cell line compared to the negative control vector-transfected glioma cells. LRF knockdown also reduced cell viability and enhanced cisplatin-induced apoptosis in glioma cells.

  3. Data indicate that transcription factors Thpok (show ZBTB7B Proteins) and LRF redundantly maintain CD4 (show CD4 Proteins)+ lineage integrity.

  4. Findings demonstrate that Pokemon suppresses Sprouty1 expression through a miR (show MLXIP Proteins)-21-mediated mechanism, affecting the growth and proliferation of liver cancer cells.

  5. Data show that Notch1 (show NOTCH1 Proteins)/Dll4 (show DLL4 Proteins)-mediated T-cell instructive signals to long-term HSCs (LT-HSCs) are suppressed by Lrf expression in the bone marrow microenvironment.

  6. These results support a critical role for LRF in transcriptional control of differentiation in oligodendrocyte lineage cells during developmental myelination in the CNS.

  7. T cells lacking Thpok (show ZBTB7B Proteins), which only displayed LRF-dependent functions, contributed to multiple effector responses, both in vitro and in vivo, with the notable exception of Th2 cell responses that control extracellular parasites

  8. study shows that LRF plays stage-specific distinct roles in osteoclast differentiation, exemplifying the delicate transcriptional regulation at work in lineage commitment

  9. Data demonstrate that the transcription factor leukemia/lymphoma-related factor (LRF) forms an obligate dimer in B cells and regulates mature B cell lineage fate and humoral immune responses via distinctive mechanisms.

  10. analysis of the miRNA-mediated interaction between leukemia/lymphoma-related factor (LRF) and alternative splicing factor/splicing factor (show SLU7 Proteins) 2 (ASF/SF2 (show SRSF1 Proteins)) affects cell senescence and apoptosis

ZBTB7A Protein Profile

Protein Summary

acts as a transcriptional repressor\; may play a role in osteoclastogenesis

Gene names and symbols associated with ZBTB7A

  • zinc finger and BTB domain containing 7A (ZBTB7A)
  • similar to zinc finger and BTB domain containing 36 (ZBTB7A)
  • zinc finger and BTB domain containing 7a (Zbtb7a)
  • 9030619K07Rik protein
  • 9130006G12Rik protein
  • AI452336 protein
  • FBI-1 protein
  • FBI1 protein
  • Lrf protein
  • OCZF protein
  • Pokemon protein
  • Zbtb7 protein
  • ZBTB7A protein
  • ZNF857A protein

Protein level used designations for ZBTB7A

zinc finger and BTB domain containing 7A , similar to zinc finger and BTB domain containing 36 , HIV-1 1st-binding protein 1 , HIV-1 inducer of short transcripts binding protein , POK erythroid myeloid ontogenic factor , POZ and Krueppel erythroid myeloid ontogenic factor , TIP21 , TTF-I-interacting peptide 21 , factor binding IST protein 1 , factor that binds to inducer of short transcripts protein 1 , leukemia/lymphoma-related factor , lymphoma related factor , zinc finger and BTB domain containing 7A, HIV-1 inducer of short transcripts binding protein , zinc finger and BTB domain-containing protein 7A , zinc finger protein 857A , leukemia/lymphoma related factor , osteoclast-derived zinc finger protein , cLRF , leukemia/lymphoma related factor cLRF

GENE ID SPECIES
468671 Pan troglodytes
705033 Macaca mulatta
51341 Homo sapiens
16969 Mus musculus
485048 Canis lupus familiaris
788491 Bos taurus
117107 Rattus norvegicus
395411 Gallus gallus
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