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The ZSCAN4 gene encodes a protein involved in telomere maintenance and with a key role in the critical feature of mouse embryonic stem (ES) cells, namely, defying cellular senescence and maintaining normal karyotype for many cell divisions in culture (Zalzman et al., 2010 [PubMed 20336070]).[supplied by OMIM, May 2010].. Additionally we are shipping ZSCAN4 Proteins (7) and many more products for this protein.
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Human Polyclonal ZSCAN4 Primary Antibody for IF, IHC (p) - ABIN501165
Hamatani, Carter, Sharov, Ko: Dynamics of global gene expression changes during mouse preimplantation development. in Developmental cell 2004
Human Polyclonal ZSCAN4 Primary Antibody for WB - ABIN531290
Ko, Azuma, Yokoyama, Yamamoto, Kyokane, Niida, Ishiguro, Ko: Inflammation increases cells expressing ZSCAN4 and progenitor cell markers in the adult pancreas. in American journal of physiology. Gastrointestinal and liver physiology 2013
the expression and function of each gene copy of Zscan4 locus in a physiological context, is reported.
Zscan4 may play critical roles during late meiotic prophase in both males and females.
ZSCAN4 indirectly interacts with TRF1 (show TERF1 Antibodies) in cancer cells. We show that ZSCAN4 plays an important role independent of telomere maintenance pathways (telomerase positive and alternative pathway) or cell lineage.
The direct interaction between Zscan4 and Rap1 (show RABGEF1 Antibodies) may explain how Zscan4 rapidly increases telomere length, yielding important information about the role of these proteins in telomere biology.
The ZSCAN4 gene encodes a protein involved in telomere maintenance and with a key role in the critical feature of mouse embryonic stem (ES) cells, namely, defying cellular senescence and maintaining normal karyotype for many cell divisions in culture (Zalzman et al., 2010
zinc finger and SCAN domain-containing protein 4
, zinc finger protein 494