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Zinc Fingers and Homeoboxes 2 Proteins (ZHX2)

The members of the zinc fingers and homeoboxes gene family are nuclear homodimeric transcriptional repressors that interact with the A subunit of nuclear factor-Y (NF-YA) and contain two C2H2-type zinc fingers and five homeobox DNA-binding domains. Additionally we are shipping ZHX2 Antibodies (105) and ZHX2 Kits (1) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ZHX2 22882 Q9Y6X8
Mouse ZHX2 ZHX2 387609 Q8C0C0
ZHX2 314988  
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Top ZHX2 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,374.17
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

ZHX2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Rat (Rattus)

More Proteins for Zinc Fingers and Homeoboxes 2 (ZHX2) Interaction Partners

Human Zinc Fingers and Homeoboxes 2 (ZHX2) interaction partners

  1. These results indicated that ZHX2 plays a critical role in the proliferation and osteo/odontogenic differentiation of SCAPs.

  2. Data show that Zinc-fingers and homeoboxes 2 (ZHX2) represses nuclear transcription factor Y alpha (show NFYA Proteins) (NF-Y)-mediated activation of multidrug resistance 1 (MDR1) transcription.

  3. Data indicate that zinc-fingers and homeoboxes 2 (ZHX2) suppresses glypican 3 (GPC3 (show GPC3 Proteins)) transcription by binding with its core promoter.

  4. Two novel markers, rs7840785 (PINX1 (show PINX1 Proteins)) and rs7844465 (ZHX2), are significantly associated with carotid intima-media thickness.

  5. Expression of a constitutively active Raf (show RAF1 Proteins) transgene enhances lymphoproliferation (show FAS Proteins), indicating a role for the Ras-MAPK (show MAPK1 Proteins) pathway in linker for activation of T cells (LAT (show LAT Proteins))-mediated autoimmune hyperproliferation.

  6. There was no significant difference in high and low percentage of HbF in GG, GA, and AA bearing individuals showing that ZHX2 gene variant has no role in ameliorating the severity of beta-thalassemia major in the South Indian population from Andhra Pradesh.

  7. results demonstrate multiple mechanisms decreasing expression of tumor suppressor gene ZHX2 in Hodgkin lymphoma cell lines

  8. Expression profiling of L-1236 cells following siRNA-mediated knockdown of ZHX2 showed inhibition of genes regulating differentiation and apoptosis, suggesting tumor suppressor activity of ZHX2.

  9. ZHX2, a transcriptional repressor, may participate in globin gene regulation.

  10. High ZHX2 is associated with metastasis in hepatocellular carcinoma.

Mouse (Murine) Zinc Fingers and Homeoboxes 2 (ZHX2) interaction partners

  1. NFAT1 (show NFAT1 Proteins) protein activation can shift oncogenic Ras/Raf (show RAF1 Proteins)/MEK (show MDK Proteins)/ERK (show EPHB2 Proteins) signaling to acting as a tumor suppressor pathway.

  2. The Zhx2 mutation resulted in a failure to suppress expression of lipoprotein lipase (show LPL Proteins), a gene normally silenced in the adult liver.

  3. molecular crosstalk between aberrant expression of Hox (show MSH2 Proteins) molecule(s) and activated Raf (show RAF1 Proteins) may have a key role in the MLL (show MLL Proteins)-fusion-mediated-leukemogenesis

  4. Zhx2 acts as a repressor of Gpc3 (show GPC3 Proteins) in the adult liver.

  5. The carboxyl terminus of Angptl4 (show ANGPTL4 Proteins) alone is sufficient to suppress angiogenesis, possibly through inhibiting the Raf (show RAF1 Proteins)/MEK (show MDK Proteins)/ERK1/2 MAP kinase (show MAPK1 Proteins) pathway in endothelial cells.

  6. These findings revealed that oxidative stress, inflammation, Ras/Raf/ERK1/2 pathway and apoptosis collectively played a crucial role in the chemopreventive activity of farnesol to inhibit the murine skin tumorigenesis.

  7. evidence presented that ZHX2 & ephrin-B1 cytoplasmic domain can interact & regulate transcription; study identifies ZHX2 as novel regulator of neural progenitor cell maintenance & suggests potential nuclear mechanism of ephrin-B function in the cortex

ZHX2 Protein Profile

Protein Summary

The members of the zinc fingers and homeoboxes gene family are nuclear homodimeric transcriptional repressors that interact with the A subunit of nuclear factor-Y (NF-YA) and contain two C2H2-type zinc fingers and five homeobox DNA-binding domains. This gene encodes member 2 of this gene family. In addition to forming homodimers, this protein heterodimerizes with member 1 of the zinc fingers and homeoboxes family.

Gene names and symbols associated with ZHX2

  • zinc fingers and homeoboxes 2 (ZHX2)
  • zinc fingers and homeoboxes 2 (zhx2)
  • zinc fingers and homeoboxes 2 (LOC100350637)
  • zinc fingers and homeoboxes 2 (Zhx2)
  • Afr-1 protein
  • Afr1 protein
  • mKIAA0854 protein
  • Raf protein
  • ZHX2 protein

Protein level used designations for ZHX2

zinc fingers and homeoboxes 2 , zinc finger and homeodomain protein 2 , zinc fingers and homeoboxes protein 2 , zinc fingers and homeoboxes protein 2-like , AFP regulator 1 , alpha-fetoprotein regulator 1 , regulator of AFP , transcription factor ZHX2 , zinc-fingers and homeoboxes 2 , alpha fetoprotein regulation 1, adult

GENE ID SPECIES
464363 Pan troglodytes
708694 Macaca mulatta
100032086 Monodelphis domestica
100066952 Equus caballus
100124305 Xenopus (Silurana) tropicalis
100173333 Pongo abelii
100225986 Taeniopygia guttata
100350637 Oryctolagus cuniculus
100395537 Callithrix jacchus
100482533 Ailuropoda melanoleuca
100546244 Meleagris gallopavo
100604500 Nomascus leucogenys
22882 Homo sapiens
482033 Canis lupus familiaris
387609 Mus musculus
314988 Rattus norvegicus
515040 Bos taurus
420351 Gallus gallus
100152952 Sus scrofa
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