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Zona Pellucida Glycoprotein 3 Proteins (ZP3)

The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. Additionally we are shipping Zona Pellucida Glycoprotein 3 Antibodies (28) and Zona Pellucida Glycoprotein 3 Kits (13) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Mouse ZP3 ZP3 22788 P10761
ZP3 7784 P21754
ZP3 114639 P97708
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Top Zona Pellucida Glycoprotein 3 Proteins at antibodies-online.com

Showing 10 out of 12 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Escherichia coli (E. coli) Human GST tag 50 μg Log in to see 21 to 26 Days
$341.00
Details
Yeast Human His tag 50 μg Log in to see 31 to 36 Days
$341.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,979.17
Details
Yeast Wild boar His tag   1 mg Log in to see 56 to 66 Days
$2,979.17
Details
Yeast Rabbit His tag   1 mg Log in to see 56 to 66 Days
$2,982.83
Details
Yeast Mesocricetus auratus His tag   1 mg Log in to see 56 to 66 Days
$2,995.67
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,999.33
Details

ZP3 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, ,
Rat (Rattus)

More Proteins for Zona Pellucida Glycoprotein 3 (ZP3) Interaction Partners

Zebrafish Zona Pellucida Glycoprotein 3 (ZP3) interaction partners

  1. The new transgenic line not only provided a convenient living marker for monitoring female gonad development, but also demonstrated that a single zp3 gene promoter is sufficient for oocyte-specific transcription.

Mouse (Murine) Zona Pellucida Glycoprotein 3 (ZP3) interaction partners

  1. Sperm arylsulfatase A (show ARSA Proteins) binds to mZP2 and mZP3 glycoproteins in a nonenzymatic manner.

  2. Cytoplasmic tails are necessary to prevent intracellular oligomerization while ensuring incorporation of processed ZP2 (show ZP2 Proteins) and ZP3 into the zona pellucida.

  3. The extreme heterogeneity of mature ZP3, with respect to both mol (show DUOXA1 Proteins). wt. and isoelectric point, is partly a consequence of the N-linked oligosaccharides and not the polypeptide chain itself.

  4. stoichiometric disposition of ZP1 (show ZP1 Proteins), ZP2 (show ZP2 Proteins), and ZP3 in the ovarian zona matrix revealed by double and triple immunolocalization studies

  5. Conserved furin (show FURIN Proteins) cleavage site not essential for secretion and integration of ZP3 into the extracellular egg coat of transgenic mice.

  6. Thr (show TRH Proteins) residues can replace the two evolutionarily conserved Ser (show SIGLEC1 Proteins) residues as acceptors for essential O-linked oligosaccharides at the sperm combining-site of ZP3 without affecting the glycoprotein's sperm receptor activity.

  7. intracellular trafficking of ZP3 was observed in growing oocytes. Replacement of the zona domain with EGFP did not prevent secretion of ZP3, suggesting the presence of trafficking signals and a cleavage site in the carboxyl terminus

  8. Le(x) is a ligand for a major class of ZP3 binding sites on mouse sperm

  9. human and mouse ZP3 proteins are quite similar, and alternative explanations of taxon-specific sperm binding warrant exploration

  10. Sperm recognize and bind to a region of ZP3 polypeptide immediately downstream of its ZP domain that is encoded by mZP3 exon-7.

Human Zona Pellucida Glycoprotein 3 (ZP3) interaction partners

  1. Epididymal CRISP1 (show CRISP1 Proteins) mediates sperm-zona pellucida binding through its interaction with ZP3.

  2. observed sequence variations in exons of ZP3 gene in women with infertility of unknown origin who exhibit abnormal zona pellucida; sperm-ovum interactions appear relatively normal in these patients [CASE REPORTS]

  3. human and mouse ZP3 proteins are quite similar, and alternative explanations of taxon-specific sperm binding warrant exploration

  4. Binding sites for recombinant zona pellucida C (ZPC) glycoprotein are located both at the N- and C-terminus of proacrosin (show ACR Proteins)

  5. Peptides rhuZP3a22 approximately 176 and rhuZP3b177 approximately 348 have a role similar to human ZP3. The mechanism of the response to the peptides involves influx of calcium, the G protein pathway, and a T-type calcium channel.

  6. induces acrosome reactions which are protein kinase-C, protein tyrosine kinase (show EPHA8 Proteins), T-type Ca2 (show CA2 Proteins)+ channels, and extracellular Ca2 (show CA2 Proteins)+ dependent

  7. a significant decrease in acrosomal exocytosis mediated by both recombinant human ZP3 (p<0.005) and ZP4 (show ZP4 Proteins) (p<0.005) was observed in presence of the immune sera

  8. The functional activity of human ZP3 resides in its C-terminal domain.

Cow (Bovine) Zona Pellucida Glycoprotein 3 (ZP3) interaction partners

  1. Polymorphism of Zp2 (show ZP2 Proteins) and the Zp3 did not show any contribution to reproductive isolation between the bovine species.

Pig (Porcine) Zona Pellucida Glycoprotein 3 (ZP3) interaction partners

  1. The expression of zona pellucida glycoprotein 3 and integrin beta-2 (show ITGB2 Proteins) in oocytes after brilliant cresyl blue staining is reported.

Zona Pellucida Glycoprotein 3 (ZP3) Protein Profile

Protein Summary

The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed primarily of three or four glycoproteins with various functions during fertilization and preimplantation development. The protein encoded by this gene is a structural component of the zona pellucida and functions in primary binding and induction of the sperm acrosome reaction. The nascent protein contains a N-terminal signal peptide sequence, a conserved ZP domain, a C-terminal consensus furin cleavage site, and a transmembrane domain. It is hypothesized that furin cleavage results in release of the mature protein from the plasma membrane for subsequent incorporation into the zona pellucida matrix. However, the requirement for furin cleavage in this process remains controversial based on mouse studies. A variation in the last exon of this gene has previously served as the basis for an additional ZP3 locus\; however, sequence and literature review reveals that there is only one full-length ZP3 locus in the human genome. Another locus encoding a bipartite transcript designated POMZP3 contains a duplication of the last four exons of ZP3, including the above described variation, and maps closely to this gene.

Gene names and symbols associated with ZP3

  • zona pellucida glycoprotein 3 (zp3)
  • zona pellucida glycoprotein 3 (Zp3)
  • zona pellucida glycoprotein 3 (sperm receptor) (ZP3)
  • zona pellucida glycoprotein 3 (sperm receptor) (Zp3)
  • zona pellucida sperm-binding protein 3 (ZP3)
  • zona pellucida sperm-binding protein 3-like (ZP3L2)
  • Zp-3 protein
  • Zp-3B protein
  • zp3.2 protein
  • ZP3A protein
  • ZP3B protein
  • ZPC protein

Protein level used designations for ZP3

zona pellucida glycoprotein 3.2 , sperm receptor , zona pellucida glycoprotein ZP3 , zona pellucida protein C , zona pellucida sperm-binding protein 3 , ZP3A/ZP3B , zona pellucida glycoprotein 3A (sperm receptor) , zona pellucida glycoprotein 3B , zona pellucida glycoprotein 3 preproprotein , zona pellucida glycoprotein ZP3B , zona pellucida C , zona pellucida 3 glycoprotein , zona pellucida glycoprotein C , zona pellucida 3 glycoprotein (sperm receptor) , zona pellucida glycoprotein 3-beta , zona pellucida glycoprotein ZP3-beta , zona pellucida protein 3-beta , zp-3-beta , zp3-beta , Sperm receptor , Zona pellucida protein C , glycoprotein hZP3 , zona pellucida C protein , zona pellucida glycoprotein 3 (sperm receptor) , zona pellucida glycoprotein 3 (sperm receptor)-like

GENE ID SPECIES
30594 Danio rerio
22788 Mus musculus
7784 Homo sapiens
280964 Bos taurus
100009185 Oryctolagus cuniculus
114639 Rattus norvegicus
493925 Felis catus
403894 Canis lupus familiaris
396927 Sus scrofa
101824371 Mesocricetus auratus
378906 Gallus gallus
415314 Gallus gallus
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