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Zona Pellucida Glycoprotein 4 Proteins (ZP4)

The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. Additionally we are shipping Zona Pellucida Glycoprotein 4 Antibodies (36) and Zona Pellucida Glycoprotein 4 Kits (1) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ZP4 57829 Q12836
Rat ZP4 ZP4 282833  
ZP4 280965 Q9BH11
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Top Zona Pellucida Glycoprotein 4 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
Yeast Rabbit His tag   1 mg Log in to see 56 to 66 Days
$3,389.83
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$3,393.50
Details

ZP4 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Cow (Bovine)

More Proteins for Zona Pellucida Glycoprotein 4 (ZP4) Interaction Partners

Human Zona Pellucida Glycoprotein 4 (ZP4) interaction partners

  1. ZO4 is highly expressed in ovarian tissue in PCOS patients with regular cycle and without hyperandrogenism; in some patients with PCOS and infertility, ZP4 mutation can be found.

  2. Human ZP4 is not sufficient to support human sperm binding to the zona pellucida in transgenic mice; other zona proteins may be needed for human gamete recognition.

  3. ZPB induces acrosomal exocytosis through a Gi independent pathway.

  4. Binding sites for recombinant zona pellucida B (ZPB) glycoprotein are located both at the N- and C-terminus of proacrosin (show ACR Proteins)

  5. induces acrosome reactions which are protein kinase-C, protein tyrosine kinase (show EPHA8 Proteins), T-type Ca2 (show CA2 Proteins)+ channels, and extracellular Ca2 (show CA2 Proteins)+ dependent

  6. a significant decrease in acrosomal exocytosis mediated by both recombinant human ZP3 (show ZP3 Proteins) (p<0.005) and ZP4 (p<0.005) was observed in presence of the immune sera

Pig (Porcine) Zona Pellucida Glycoprotein 4 (ZP4) interaction partners

  1. Porcine zona pellucida glycoprotein ZP4 is responsible for the sperm-binding activity of the ZP3 (show ZP3 Proteins)/ZP4 complex

Zona Pellucida Glycoprotein 4 (ZP4) Protein Profile

Protein Summary

The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed primarily of three or four glycoproteins with various functions during fertilization and preimplantation development. The nascent protein contains a N-terminal signal peptide sequence, a conserved ZP domain, a consensus furin cleavage site, and a C-terminal transmembrane domain. It is hypothesized that furin cleavage results in release of the mature protein from the plasma membrane for subsequent incorporation into the zona pellucida matrix. However, the requirement for furin cleavage in this process remains controversial based on mouse studies. Previously, this gene has been referred to as ZP1 or ZPB and thought to have similar functions as mouse Zp1. However, a human gene with higher similarity and chromosomal synteny to mouse Zp1 has been assigned the symbol ZP1 and this gene has been assigned the symbol ZP4.

Gene names and symbols associated with ZP4

  • zona pellucida glycoprotein 4 (zp4-a)
  • zona pellucida glycoprotein 4 (zp4)
  • zona pellucida glycoprotein 4 (ZP4)
  • zona pellucida glycoprotein 4 (Zp4)
  • lzpb-a protein
  • MGC154827 protein
  • MGC154888 protein
  • TAC4 protein
  • xlZPB protein
  • ZBP protein
  • ZP protein
  • Zp-4 protein
  • Zp-X protein
  • ZP1 protein
  • ZP3-ALPHA protein
  • ZPB protein

Protein level used designations for ZP4

zona pellucida glycoprotein 4 , vitelline envelope 37k glycoprotein xlZPB , egg envelope component ZPB , zona pellucida sperm-binding protein 4 , zona pellucida B protein , tachykinin 4 , zona pellicida protein B , zona pellucida sperm-binding protein 4-like , zona pellucida protein B , zona pellucida 4 , zona pellucida B glycoprotein , zona pellucida glycoprotein 3-alpha , zona pellucida glycoprotein ZP3-alpha , zona pellucida protein 3-alpha , zp-3-alpha , zp3-alpha sperm-binding glycoprotein , RC55 , zona pellucida glycoprotein X , zona pellucida glycoprotein ZP-X

GENE ID SPECIES
394364 Xenopus laevis
394445 Xenopus (Silurana) tropicalis
395692 Gallus gallus
442977 Canis lupus familiaris
469721 Pan troglodytes
709637 Macaca mulatta
779327 Xenopus laevis
100134840 Meleagris gallopavo
100406555 Callithrix jacchus
57829 Homo sapiens
282833 Rattus norvegicus
280965 Bos taurus
493791 Felis catus
397111 Sus scrofa
100009131 Oryctolagus cuniculus
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