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Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Additionally we are shipping ZWILCH Antibodies (44) and many more products for this protein.
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Zwilch localizes to kinetochores and kinetochore microtubules in a manner identical to ZW10 and ROD.
Other name: HZwilch. Homologue of Drosophila Zwilch (CG18729). Localizes to the kinetochore during prometaphase and metaphase of HeLa cells. Complexed with human ROD and human ZW10 (show ZW10 Proteins), similar to situation in Drosophila.
Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores (By similarity).
Zwilch, kinetochore associated, homolog
, protein zwilch homolog
, homolog of Drosophila Zwilch