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anti-alpha 1, 4-Galactosyltransferase (A4GALT) Antibodies

The protein encoded by A4GALT catalyzes the transfer of galactose to lactosylceramide to form globotriaosylceramide, which has been identified as the P(k) antigen of the P blood group system. Additionally we are shipping A4GALT Proteins (6) and A4GALT Kits (1) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
A4GALT 53947 Q9NPC4
A4GALT 239559 Q67BJ4
A4GALT 63888 Q9JI93
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Top anti-A4GALT Antibodies at antibodies-online.com

Showing 10 out of 46 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB WB Suggested Anti-A4GALT Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: HT1080 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB A4GALT Antibody (N-term) (ABIN654075) western blot analysis in 293 cell line lysates (35 µg/lane). This demonstrates the A4GALT antibody detected the A4GALT protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, WB A4GALT Antibody 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated IF (p), IHC (p) Antigen: 0.2 µg/100 µL  Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000;  Secondary: HRP conjugated Goat-Anti-Rabbit IgG at 1: 5000;  TMB staining;  Read the data in MicroplateReader by 450 Formalin-fixed and paraffin embedded human placenta labeled with Anti-A4GALT Polyclonal Antibody, Unconjugated (ABIN873268) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Rabbit Biotin ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Alexa Fluor 594 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 647 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 488 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Biotin IHC (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details

A4GALT Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-A4GALT Antibodies

  1. Human Polyclonal A4GALT Primary Antibody for EIA, WB - ABIN951384 : Zumbrun, Hanson, Sinclair, Freedy, Melton-Celsa, Rodriguez-Canales, Hanson, OBrien: Human intestinal tissue and cultured colonic cells contain globotriaosylceramide synthase mRNA and the alternate Shiga toxin receptor globotetraosylceramide. in Infection and immunity 2010 (PubMed)
    Show all 3 references for ABIN951384

  2. Human Polyclonal A4GALT Primary Antibody for WB - ABIN2782909 : Hellberg, Schmidt-Melbye, Reid, Olsson: Expression of a novel missense mutation found in the A4GALT gene of Amish individuals with the p phenotype. in Transfusion 2008 (PubMed)

  3. Human Polyclonal A4GALT Primary Antibody for WB - ABIN654075 : Okuda, Nakayama: Identification and characterization of the human Gb3/CD77 synthase gene promoter. in Glycobiology 2008 (PubMed)

More Antibodies against A4GALT Interaction Partners

Human alpha 1, 4-Galactosyltransferase (A4GALT) interaction partners

  1. Mutation in the A4GALT gene is associated with rare p phenotype in P1Pk blood group (show DARC Antibodies) system.

  2. The results of this investigation demonstrate a consistent association of A4GALT SNPs rs2143918 and rs5751348 with the P1/P2 phenotypes and suggest that SNP rs5751348 may lead to allelic variations in A4GALT gene expression

  3. these data elucidate a new explanation underlying the p phenotype, implicating the deleted regions of A4GALT as crucial for P1 and P(k) synthesis, possibly due to loss of binding sites for erythroid transcription factors.

  4. P1-decorated PSGL-1 (show SELPLG Antibodies)/mIgG2b bound with high avidity to both Stx1 (show STX1A Antibodies) and Stx2 (show STX2 Antibodies), and as such constitutes a potential therapeutic inhibitor of these toxins.

  5. Results suggest that the C631G mutation alters the acceptor specificity of Gb3/CD77 synthase, rendering it able to catalyze synthesis of the Gal (show GAL Antibodies)(alpha1-4)Gal (show GAL Antibodies) and Gal (show GAL Antibodies)(alpha1-4)GalNAc moieties.

  6. Increased globotriaosylceramide levels are detected in a transgenic mouse expressing human alpha1,4-galactosyltransferase in a mouse model for treating Fabry disease.

  7. Data showed that GRINA-C was associated with Gb3 synthase, and may demonstrate a new type of posttranscriptional regulation of glycosyltransferases.

  8. of A4GALT mRNA in cultured human bone marrow cells revealed novel transcripts containing only the noncoding exon 1 and a sequence (here termed exon 2a) from intron 1.

  9. We established by quantitative real-time PCR that both fresh colonic epithelial sections and HCT-8 cells express Gb3 synthase mRNA and the alternate Shiga toxin receptor globotetraosylceramide.

  10. The P blood group (show DARC Antibodies) phenotype is due to several disctint nonfunctional alleles of A4GALT without any predominant allele.

Mouse (Murine) alpha 1, 4-Galactosyltransferase (A4GALT) interaction partners

A4GALT Antigen Profile

Protein Summary

The protein encoded by this gene catalyzes the transfer of galactose to lactosylceramide to form globotriaosylceramide, which has been identified as the P(k) antigen of the P blood group system. The encoded protein, which is a type II membrane protein found in the Golgi, is also required for the synthesis of the bacterial verotoxins receptor.

Gene names and symbols associated with A4GALT

  • alpha 1,4-galactosyltransferase (A4GALT) antibody
  • alpha 1,4-galactosyltransferase (A4galt) antibody
  • A4GALT1 antibody
  • A14GALT antibody
  • Gb3 antibody
  • Gb3S antibody
  • P(k) antibody
  • P1 antibody
  • P1PK antibody
  • PK antibody

Protein level used designations for A4GALT

CD77 synthase , GB3 synthase , P blood group (P one antigen) , P(k) antigen synthase , P1/Pk synthase , UDP-galactose:beta-D-galactosyl-beta1-R 4-alpha-D-galactosyltransferase , alpha-1,4-N-acetylglucosaminyltransferase , alpha4Gal-T1 , globotriaosylceramide synthase , lactosylceramide 4-alpha-galactosyltransferase , Gb3 synthase , Gb3/CD77 synthase , alpha-1,4-galactosyltransferase , alpha 1,4-galactosyltransferase (globotriaosylceramide synthase)

GENE ID SPECIES
53947 Homo sapiens
239559 Mus musculus
63888 Rattus norvegicus
418223 Gallus gallus
481222 Canis lupus familiaris
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