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alpha 1 Microglobulin/bikunin Proteins (AMBP)

AMBP encodes a complex glycoprotein secreted in plasma. Additionally we are shipping alpha 1 Microglobulin/bikunin Antibodies (164) and alpha 1 Microglobulin/bikunin Kits (116) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
AMBP 11699 Q07456
AMBP 259 P02760
AMBP 25377 Q64240
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Top alpha 1 Microglobulin/bikunin Proteins at

Showing 10 out of 56 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 Days
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 Days
HOST_Escherichia coli (E. coli) Human His tag 50 μg Log in to see 7 to 8 Days
HOST_Human Cells Human His tag 100 μg Log in to see 16 Days
HOST_Escherichia coli (E. coli) Rat His tag,GST tag 100 μg Log in to see 11 to 13 Days
HOST_Escherichia coli (E. coli) Mouse His tag,GST tag 100 μg Log in to see 11 to 13 Days
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
HOST_Mammalian Cells Human His tag   10 μg Log in to see 5 Days

AMBP Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) ,
Human , , , , , ,
, ,
Rat (Rattus) ,

Top referenced alpha 1 Microglobulin/bikunin Proteins

  1. Human AMBP Protein expressed in Escherichia coli (E. coli) - ABIN667966 : Sala, Campagnoli, Perani, Romano, Labò, Monzani, Minchiotti, Galliano: Human alpha-1-microglobulin is covalently bound to kynurenine-derived chromophores. in The Journal of biological chemistry 2004 (PubMed)
    Show all 2 references for ABIN667966

More Proteins for alpha 1 Microglobulin/bikunin (AMBP) Interaction Partners

Mouse (Murine) alpha 1 Microglobulin/bikunin (AMBP) interaction partners

  1. In this review, the use of genetically targeted mice selectively lacking UTI provides evidence of a therapeutic option for experimental endotoxin-related inflammatory disorders such as acute lung injury and acute liver injury.

  2. expression of the AMBP gene transcript and its two protein products, alpha(1)-microglobulin and bikunin, in embryogenesis

  3. UTI inhibited LPS (show TLR4 Proteins)-induced production of TNF-alpha (show TNF Proteins) by inhibiting activation of the extracellular signal-regulated protein kinases 1/2-Egr-1 (show EGR1 Proteins) pathway in monocytes, which might at least partly contribute to reduction of hypotension

  4. UTI protects against systemic inflammatory response and subsequent organ injury induced by bacterial endotoxin.

  5. results indicate that endogenous UTI is protective against acute lung injury induced by bacterial endotoxin, at least partly, via the antioxidative properties

  6. increased sensitivity of Bik (show BIK Proteins)-/- mice to lung metastasis in vivo is due to a lack of circulating proteins of the inter-alpha inhibitor family, especially bikunin

  7. UTI reduces NF-kappaB (show NFKB1 Proteins) activation and downregulates the expression of its related mediators, followed by the inhibition of neutrophil aggregation and infiltration in hepatic ischemia reperfusion injury

  8. Report impaired liver regeneration with humoral and genetic disturbances in urinary trypsin inhibitor-deficient mice.

  9. UTI protects against severe liver injury and subsequent coagulatory disturbance which was mediated, at least partly, through the suppression of TNF-alpha (show TNF Proteins) production along with its antiprotease activity.

Human alpha 1 Microglobulin/bikunin (AMBP) interaction partners

  1. There were significantly higher serum concentrations of fetal hemoglobin (show HBB Proteins) and alpha1-microglobulin and significantly lower first trimester serum concentrations of hemopexin (show HPX Proteins) in patients who later developed preeclampsia.

  2. Prophylactic UTI maintains the endothelial barrier function, increases VE-cadherin (show CDH5 Proteins) expression, and inhibits the phosphorylation of VE-cadherin (show CDH5 Proteins) at Tyr658 under inflammatory conditions

  3. Data suggest that Mg2 (show MUC7 Proteins)+ or Mn2+ (but not Ca2 (show CA2 Proteins)+) induce a conformational change in inter-alpha-inhibitor (ITIH1 (show ITIH1 Proteins) and ITIH2 (show ITIH2 Proteins)) and a bikunin/chondroitin sulfate-dependent increase in thermodynamic stability; bikunin binds adjacent to the two heavy chains.

  4. results indicate a reduced UTI level in CSF (show CSF2 Proteins) of MS and NMO patients. The levels were associated with the severity of the two demyelinating diseases during relapse

  5. Heavy chain transfer by tumor necrosis factor (show TNF Proteins)-stimulated gene 6 to the bikunin proteoglycan (show Vcan Proteins).

  6. Decreased bikunin mRNA level in renal cells might be associated with poor prognosis of renal carcinoma.

  7. The antioxidative protection of cells and collagen by A1M is totally dependent on its C34 amino acid residue.

  8. Label-free quantitative comparison of DN urinary exosomes vs control group and SRM (show SRM Proteins) further validation, resulted in the discovery of a panel of three proteins (AMBP, MLL3 and VDAC1 (show VDAC1 Proteins)) which changes in DN.

  9. The high level of serum AMBP could predict the poor response of the AGC (show ACAN Proteins) patients.

  10. our findings suggest that urine bikunin level, as well as proteinuria, could represent a useful parameter for monitoring renal function in those patients that do not present any symptoms of renal insufficiency.

Pig (Porcine) alpha 1 Microglobulin/bikunin (AMBP) interaction partners

  1. The aim of this research was to screen polymorphism and to perform association study of porcine AMBP, GC and PPP1R3B (show PPP1R3B Proteins) genes with meat quality traits.

alpha 1 Microglobulin/bikunin (AMBP) Protein Profile

Protein Summary

This gene encodes a complex glycoprotein secreted in plasma. The precursor is proteolytically processed into distinct functioning proteins: alpha-1-microglobulin, which belongs to the superfamily of lipocalin transport proteins and may play a role in the regulation of inflammatory processes, and bikunin, which is a urinary trypsin inhibitor belonging to the superfamily of Kunitz-type protease inhibitors and plays an important role in many physiological and pathological processes. This gene is located on chromosome 9 in a cluster of lipocalin genes.

Gene names and symbols associated with AMBP

  • alpha 1 microglobulin/bikunin (Ambp)
  • alpha-1-microglobulin/bikunin precursor (AMBP)
  • alpha-1-microglobulin/bikunin precursor (Ambp)
  • pregnancy zone protein (Pzp)
  • pregnancy-zone protein (Pzp)
  • A1m protein
  • A2m protein
  • AI194774 protein
  • AI893533 protein
  • ASPI protein
  • EDC1 protein
  • HCP protein
  • HI-30 protein
  • HI30 protein
  • IATIL protein
  • Intin4 protein
  • ITI protein
  • ITIL protein
  • ITILC protein
  • MAM protein
  • UTI protein

Protein level used designations for AMBP

alpha-1-microglobulin/bikunin , protein AMBP , Urinary Trypsin Inhibitor , polyprotein , ulinastatin , bikunin , complex-forming glycoprotein heterogeneous in charge , growth-inhibiting protein 19 , inter-alpha-trypsin inhibitor light chain , protein HC , trypstatin , uristatin , uronic-acid-rich protein , Alpha-1 microglobulin/bikunin , alpha 1 microglobulin/bikunin , alpha-1 microglobulin , inter-alpha-trypsin inhibitor (protein HC), light , Protein AMBP , alpha 1 macroglobulin , alpha-2-M , alpha-2-macroglobulin , alpha-1-M , alpha-1-macroglobulin , alpha-1-macroglobulin 165 kDa subunit

100379539 Cavia porcellus
11699 Mus musculus
259 Homo sapiens
25377 Rattus norvegicus
397593 Sus scrofa
280996 Bos taurus
481685 Canis lupus familiaris
770795 Gallus gallus
101104205 Ovis aries
101840661 Mesocricetus auratus
11287 Mus musculus
252922 Rattus norvegicus
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