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AFP encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Additionally we are shipping alpha Fetoprotein Kits (87) and alpha Fetoprotein Proteins (56) and many more products for this protein.
Showing 10 out of 1059 products:
Human Monoclonal alpha Fetoprotein Primary Antibody for WB - ABIN659001
Liu, Cheng, Sheng, Lu, Xu, Long, Zhu, Wang: Clinicopathologic features and prognostic factors in alpha-fetoprotein-producing gastric cancers: analysis of 104 cases. in Journal of surgical oncology 2010
Show all 5 references for ABIN659001
Human Monoclonal alpha Fetoprotein Primary Antibody for IHC (p) - ABIN1105327
DEustachio, Ingram, Tilghman, Ruddle: Murine alpha-fetoprotein and albumin: two evolutionarily linked proteins encoded on the same mouse chromosome. in Somatic cell genetics 1981
Show all 3 references for ABIN1105327
Human Polyclonal alpha Fetoprotein Primary Antibody for EIA, IHC (p) - ABIN356915
Yamashita, Forgues, Wang, Kim, Ye, Jia, Budhu, Zanetti, Chen, Qin, Tang, Wang: EpCAM and alpha-fetoprotein expression defines novel prognostic subtypes of hepatocellular carcinoma. in Cancer research 2008
Show all 3 references for ABIN356915
Human Polyclonal alpha Fetoprotein Primary Antibody for EIA, IHC (p) - ABIN356914
Chen, Ho, Wong, Lee, Lai: Single nucleotide polymorphism in the promoter region of human alpha-fetoprotein (AFP) gene and its significance in hepatocellular carcinoma (HCC). in European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology 2007
Show all 3 references for ABIN356914
Human Polyclonal alpha Fetoprotein Primary Antibody for IHC (p), WB - ABIN388199
Cajaiba, Sarita-Reyes, Zambrano, Reyes-Múgica: Mesenchymal hamartoma of the liver associated with features of Beckwith-Wiedemann syndrome and high serum alpha-fetoprotein levels. in Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society 2007
Show all 2 references for ABIN388199
Human Monoclonal alpha Fetoprotein Primary Antibody for EIA, IHC (p) - ABIN120683
Stefanovua, Horejsui, Kristofovua, Angelisovua, Zizkovskuy, Hilgert: Monoclonal antibodies against human alpha-fetoprotein. Exploitation of an unusual calcium-dependent interaction with the antigen for analytical and preparative purposes. in Journal of immunological methods 1988
Human Polyclonal alpha Fetoprotein Primary Antibody for IHC (fro), IHC (p) - ABIN115282
MacDonald, Kelly: The rapid quantitation of serum alpha-fetoprotein by two-site micro enzyme immunoassay. in Clinica chimica acta; international journal of clinical chemistry 1978
Human Monoclonal alpha Fetoprotein Primary Antibody for EIA, IHC (fro) - ABIN1105330
Tsung, Milunsky, Alpert: Derivation and characterization of a monoclonal hybridoma antibody specific for human alpha-fetoprotein. in Journal of immunological methods 1981
Human Polyclonal alpha Fetoprotein Primary Antibody for EIA, IF - ABIN783673
Lafuste, Robert, Mondon, Danan, Rossi, Duc-Goiran, Mignot, Nunez, Benassayag, Ferré: Alpha-fetoprotein gene expression in early and full-term human trophoblast. in Placenta 2002
endogenous AFP expression in the perinatal liver is reduced in the absence of beta-catenin (show CTNNB1 Antibodies), suggesting that beta-catenin (show CTNNB1 Antibodies) regulates AFP during liver development.
Findings indicate that AFP expressed under experimental cryptorchid conditions plays a role as a regulatory factor in spermatogenesis and in hepatic generation.
AFP mRNA and VEGF-C (show VEGFC Antibodies) mRNA in peripheral blood were significantly correlated with recurrence and metastasis of hepatocellular carcinoma.
A DEHP treatment-induced phenotype was identified with lack of glycogen (show GYS1 Antibodies) accumula-tion and intracytoplasmic localization of beta-catenin (show CTNNB1 Antibodies) which was associated with increased AFP gene expression.
The deficits observed in parental behavior of AFP knockout females could not be explained by any changes in olfactory function, novelty recognition or anxiety
Foxa1 (show FOXA1 Antibodies) acts as a pioneer transcription factor in de novo activation of Afp, by exploiting a lack of methylation at juxtaposed transposed elements
The level of AFP mRNA in peripheral blood may indicate recurrence and/or metastasis after curative resection of hepatocellular carcinoma.
AFP affects cell proliferation by binding its receptor to trigger the signal transduction pathway of cAMP-PKA and alter the expression of K- ras (show HRAS Antibodies) p21 (show D4S234E Antibodies) genes
A murine Nkx2.8 (show NKX2-6 Antibodies) was isolated from the Hepal-6 cell line and showed oligonucleotide binding competitive with fetoprotein transcription factor (show NR5A2 Antibodies).
The mouse alpha-fetoprotein promoter is repressed in HepG2 hepatoma cells by hepatocyte nuclear factor-3 (show FOXA1 Antibodies)
Elevated insulin (show INS Antibodies) resistance, leptin (show LEP Antibodies), serum iron, ferritin (show FTL Antibodies), mean platelet volume, NLR (show CXCR5 Antibodies), and advanced fibrosis, as well as decreased platelet count and serum albumin (show ALB Antibodies), are independently associated with an elevated AFP level in chronic hepatitis C.
VEGF (show VEGFA Antibodies) could be a potential biomarker for HCC (show FAM126A Antibodies), while AFP could be used to distinguish between patients with HCC (show FAM126A Antibodies) and cirrhosis or HCV.
Data indicate the diagnostic criteria of chorionic gonadotropin beta subunit (show CGB Antibodies) (beta-hCG (show CGA Antibodies)) and alpha-Fetoprotein (alphaFP) in CSF (show CSF2 Antibodies) and serum, which may advance the early and formal diagnosis of intracranial germ cell tumors (ICGCTs).
The risk of post-transplant hepatocellular carcinoma recurrence is dependent on the last pre-transplant AFP regardless of its previous dynamics.
Results show that AFP normalization within three months after stereotactic body radiotherapy (SBRT) is a prognostic surrogate for overall survival and progression free survival in patients with small hepatocellular carcinoma.
A high level of serum AFP is an independent prognostic factor in gastric cancer and can be used for evaluating the prognosis of gastric cancers whether in the presence or absence of liver metastasis.
Simultaneous determination of the AFP, AFP-L3 and TP53 (show TP53 Antibodies) yielded a better diagnostic accuracy and sensitivity in the detection of HCCs (show HCCS Antibodies) than each biomarker alone.
the accuracy of des (show DES Antibodies)-gamma-carboxy prothrombin (show F2 Antibodies) for distinguishing hepatocellular carcinoma from various controls was 6.2-9.7% higher than that of AFP
Integration of the AFP delta-slope with conventional criteria may further improve HCC (show FAM126A Antibodies) patient selection for liver transplantation and treatment outcomes.
AFP remained the best single marker, and the combined use of AFP with prothrombin (show F2 Antibodies) precursor or DKK-1 (show DKK1 Antibodies) had the best diagnostic performance compared to all other possible combinations of the four biomarkers, even in early stage hepatocellular carcinoma.
Equine alpha-fetoprotein seems to be an important indicator of fetal well-being in horses.
This study confirmed that alpha-fetoprotein (AFP) is present in the fetal fluids of mares during the third trimester of pregnancy; experimentally induced placentitis was associated with an elevation in maternal plasma concentrations of AFP.
This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.
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