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anti-beta-2-Microglobulin (B2M) Antibodies

B2M encodes a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. Additionally we are shipping beta-2-Microglobulin Proteins (128) and beta-2-Microglobulin Kits (71) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
B2M 24223 P07151
B2M 12010 P01887
B2M 567 P61769
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Top anti-beta-2-Microglobulin Antibodies at antibodies-online.com

Showing 10 out of 445 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, IHC (p) 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated EIA, IHC (p) 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Mouse Un-conjugated EIA, FACS, IHC (p), IP, RIA, WB   0.1 mg Log in to see 6 to 8 Days
$253.00
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-B2M Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: Human Thymus 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse FITC EIA, FACS, IHC (p), IP, RIA, WB   0.1 mg Log in to see 6 to 8 Days
$308.00
Details
Human Mouse Biotin EIA, FACS, IHC (p), IP, RIA, WB   0.1 mg Log in to see 6 to 8 Days
$308.00
Details
Human Mouse HRP EIA, FACS, IHC (p), IP, RIA, WB   0.1 mg Log in to see 6 to 8 Days
$324.50
Details
Human Rabbit Un-conjugated WB Western blot analysis of B2M Antibody (C-term) (ABIN389260) in Hela cell line lysates (35 µg/lane). B2M (arrow) was detected using the purified polyclonal antibody. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of B2M(arrow) using rabbit polyclonal B2M Antibody (C-term) (ABIN389259). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the B2M gene (Lane 2) (Origene Technologies). Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with B2M antibody (C-term) (ABIN389259), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of B2M (arrow) using rabbit polyclonal B2M Antibody (N-term) (ABIN389258). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the B2M gene (Lane 2) (Origene Technologies). Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with B2M antibody (N-term) (ABIN389258), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details

B2M Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-beta-2-Microglobulin Antibodies

  1. Human Monoclonal B2M Primary Antibody for EIA, FACS - ABIN112400 : Khurana, Traum, Aivado, Wells, Guerrero, Grall, Libermann, Schachter: Urine proteomic profiling of pediatric nephrotic syndrome. in Pediatric nephrology (Berlin, Germany) 2006 (PubMed)
    Show all 4 references for ABIN112400

  2. Human Monoclonal B2M Primary Antibody for EIA, FACS - ABIN112398 : Hilgert, Horejsí, Kristofová: The use of murine monoclonal antibody B2M-01 for detection and purification of human beta 2-microglobulin. in Folia biologica 1985 (PubMed)
    Show all 4 references for ABIN112398

  3. Human Polyclonal B2M Primary Antibody for EIA, IHC (p) - ABIN357931 : Sakata, Chatani, Kameda, Sakurai, Naiki, Goto: Kinetic coupling of folding and prolyl isomerization of beta2-microglobulin studied by mutational analysis. in Journal of molecular biology 2008 (PubMed)
    Show all 3 references for ABIN357931

  4. Human Polyclonal B2M Primary Antibody for EIA, IHC (p) - ABIN357932 : Huang, Havel, Zhau, Qian, Lue, Chu, Nomura, Chung: Beta2-microglobulin signaling blockade inhibited androgen receptor axis and caused apoptosis in human prostate cancer cells. in Clinical cancer research : an official journal of the American Association for Cancer Research 2008 (PubMed)
    Show all 3 references for ABIN357932

  5. Human Polyclonal B2M Primary Antibody for FACS, IHC (p) - ABIN389259 : Gattoni-Celli, Kirsch, Timpane, Isselbacher: Beta 2-microglobulin gene is mutated in a human colon cancer cell line (HCT) deficient in the expression of HLA class I antigens on the cell surface. in Cancer research 1992 (PubMed)
    Show all 2 references for ABIN389259

  6. Human Polyclonal B2M Primary Antibody for WB - ABIN2786771 : Platt, Routledge, Homans, Radford: Fibril growth kinetics reveal a region of beta2-microglobulin important for nucleation and elongation of aggregation. in Journal of molecular biology 2008 (PubMed)

More Antibodies against beta-2-Microglobulin Interaction Partners

Mouse (Murine) beta-2-Microglobulin (B2M) interaction partners

  1. The results show that, although other factors influence the fibril growth kinetics, a striking difference in the solubility of the proteins is a key determinant of the different amyloidogenicity of human B2M and mouse B2M.

  2. Use of shRNA against beta-2-microglobulin offers a simple and effective approach to minimize immunogenicity of the main cellular components of cardiac tissue constructs in non-syngeneic recipients.

  3. systemic B2M accumulation in aging blood promotes age-related cognitive dysfunction and impairs neurogenesis

  4. Because all forms of H-2K(b) are internalized but little beta2m-receptive heavy chain is present at the cell surface, it is likely that beta2m dissociation and recognition of the heavy chain for lysosomal degradation take place in an endocytic compartment.

  5. We report a novel dichotomous role of beta2m and CD1d, whereby these molecules differently regulate autoimmunity against phospholipid versus non-phospholipid autoantigens.

  6. The goal of the present work was to study peculiarities in functioning of proteasomes and associated signaling pathways along with evaluation of NeuN (show RBFOX3 Antibodies) and gFAP (show GFAP Antibodies) expression in different sections of the brain in mice.

  7. MHC I and b2m genes are both expressed in in human as well as mice during the developmental stages of cerebellar cortex

  8. Knocking out beta 2 microglobulin abolishes NMDAR-dependent LTD in area CA1 of adult mouse hippocampus and is accompanied by memory deficits. MHC class I expression could be an unexpected cause of disrupted synaptic plasticity and cognitive deficits.

  9. This study demonistrated that Deletion of beta-2-microglobulin ameliorates spinal cord lesion load and promotes recovery of brainstem NAA levels in a murine model of multiple sclerosis

  10. Data show that tapasin (show TAPBP Antibodies) expression is enhanced by beta 2-microglobulin via both transcriptional and post-transcriptional mechanisms.

Human beta-2-Microglobulin (B2M) interaction partners

  1. Overexpression of B2M are associated with invasion, metastasis of the pancreatic ductal adenocarcinoma.

  2. Serum Beta-2 Microglobulin level is elevated in Chronic Hepatitis C related chronic liver diseases and may be used as a marker for Chronic Hepatitis C disease progression towards cirrhosis and carcinoma.

  3. Data suggest that, in modeling early assembly mechanisms for amyloidogenic beta2-microglobulin (B2M and/or truncated B2M, crosslinked and native), domain-swapped hinge region of B2M is key to both intra-molecular and inter-molecular interactions.

  4. The results show that, although other factors influence the fibril growth kinetics, a striking difference in the solubility of the proteins is a key determinant of the different amyloidogenicity of human B2M and mouse B2M.

  5. beta2M-mediated VEGFR-2/Akt/mTOR phosphorylation and tumor angiogenesis was significantly suppressed by over-expression of DKK-3.

  6. ESAT-6/ESAT-6:CFP-10 can enter into the endoplasmic reticulum where it sequesters beta2M to inhibit cell surface expression of MHC-I-beta2M complexes, resulting in downregulation of class I-mediated antigen presentation.

  7. The study presents the X-ray crystallographic structures of three families of oligomers formed by macrocyclic peptides containing a heptapeptide sequence derived from the amyloidogenic E chain of beta 2-microglobulin (B2M).

  8. Serum cystatin C (show CST3 Antibodies), urine NAG (show NAGLU Antibodies), RBP (show RBP4 Antibodies), and ET-1 (show EDN1 Antibodies) levels were found to be insufficient for the evaluation of SCD (show SCD Antibodies) nephropathy. Increased B2M/creatinie levels can be valuable in estimating possible glomerular and tubular damage in SCD (show SCD Antibodies).

  9. Unfolding of the C-terminal portion of human beta 2 microglobulin may be related to amyloidogenicity.

  10. The results suggest that the interaction between beta2m fibrils and membranes of endosomal origin may play a role in the molecular mechanism of beta2m amyloid-associated osteoarticular tissue destruction in DRA.

Pig (Porcine) beta-2-Microglobulin (B2M) interaction partners

  1. B2M contains alpha-helix, beta-sheet, turn, and random coil.

Rhesus Monkey beta-2-Microglobulin (B2M) interaction partners

Zebrafish beta-2-Microglobulin (B2M) interaction partners

beta-2-Microglobulin (B2M) Antigen Profile

Protein Summary

This gene encodes a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia.

Gene names and symbols associated with B2M

  • beta-2-microglobulin (B2M) antibody
  • beta-2 microglobulin (b2m) antibody
  • beta-2 microglobulin (B2m) antibody
  • beta-2-microglobulin (b2m) antibody
  • beta-2-microglobulin (B2m) antibody
  • Beta-2-microglobulin-like (LOC100350679) antibody
  • b2m antibody
  • b2m-W01 antibody
  • b2m-W03 antibody
  • b2m-Z01 antibody
  • b2m-Z02 antibody
  • b2m-Z03 antibody
  • B2MG antibody
  • beta2-m antibody
  • beta2m antibody
  • bwm antibody
  • Ly-m11 antibody
  • wu:fa94c05 antibody
  • wu:fb10a09 antibody

Protein level used designations for B2M

beta-2-microglobulin , beta-2 microglobulin , Beta-2-microglobulin , beta-2-microglobulin C-terminal fragment (55 AA) , beta2 microglobulin , beta 2-m , beta 2-microglobulin , beta chain of MHC class I molecules , beta-2-microglobin , lactollin , beta 2 microglobulin , beta-2-microglobulin-like protein , beta 2 microglobulin (54 AA)

GENE ID SPECIES
100174579 Pongo abelii
554191 Monodelphis domestica
100136933 Salmo salar
100381194 Papio anubis
100304470 Ictalurus punctatus
24223 Rattus norvegicus
12010 Mus musculus
100379556 Cavia porcellus
100689409 Cricetulus griseus
567 Homo sapiens
397033 Sus scrofa
414830 Gallus gallus
712428 Macaca mulatta
280729 Bos taurus
494145 Felis catus
100034203 Equus caballus
443295 Ovis aries
100855741 Canis lupus familiaris
30400 Danio rerio
101843036 Mesocricetus auratus
100404307 Callithrix jacchus
450170 Pan troglodytes
791104 Ornithorhynchus anatinus
398171 Xenopus laevis
478284 Canis lupus familiaris
100350679 Oryctolagus cuniculus
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