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BACE1 Proteins

(Beta-secretase 1 (BACE1))
Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is the protein encoded by this gene. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi. Multiple transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, May 2011].
BACE1 Protein (AA 22-457) (Fc Tag) BACE1 Protein (AA 22-457) (Fc Tag) BACE1 Protein (AA 22-457) (Fc Tag) (ABIN7273905)

BACE1 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

BACE1 Protein (AA 22-457) (His tag) BACE1 Protein (AA 22-457) (His tag) BACE1 Protein (AA 22-457) (His tag) (ABIN7273904)

BACE1 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

BACE1 Protein (AA 22-457) (His tag) BACE1 Protein (AA 22-457) (His tag) BACE1 Protein (AA 22-457) (His tag) (ABIN7273906)

BACE1 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

BACE1 Proteins by Grade

Find BACE1 Proteins with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

BACE1 Proteins by Origin

Find BACE1 Proteins for a variety of species such as anti-Human BACE1, anti-Mouse BACE1, anti-Rat BACE1. The species listed below are among those available. Click on a link to go to the corresponding products.

BACE1 Proteins by Source

Here you will find BACE1 Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

BACE1 Proteins by Protein Type

Here you can find BACE1 Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

BACE1 Proteins by Application

Find BACE1 Proteins validated for a specific application such as WB, ELISA, SDS, Imm. Some of the available applications are listed below. Click on a link to go to the corresponding products.

BACE1 Proteins by Biological Activity

Find BACE1 Proteins with a specific Biological Activity. The Biological Activity listed below are among those available. Click on a link to go to the corresponding products.

Popular BACE1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7273905
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7273904
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7273906
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7121998
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1346345
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN7320444
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3089880
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3120522
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3114008
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3120523
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
  • (1)
Cat. No. ABIN2180626
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7505103
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
Cat. No. ABIN7519704
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7391801
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7411204
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our BACE1 Proteins

Mycroft-West, Devlin, Cooper, Procter, Miller, Fernig, Guerrini, Guimond, Lima, Yates, Skidmore: "Inhibition of BACE1, the β-secretase implicated in Alzheimer's disease, by a chondroitin sulfate extract from Sardina pilchardus." in: Neural regeneration research, Vol. 15, Issue 8, pp. 1546-1553, (2020) (PubMed).

Peters-Libeu, Campagna, Mitsumori, Poksay, Spilman, Sabogal, Bredesen, John: "sAβPPα is a Potent Endogenous Inhibitor of BACE1." in: Journal of Alzheimer's disease : JAD, Vol. 47, Issue 3, pp. 545-55, (2015) (PubMed).

Aliases for BACE1 Proteins

beta-secretase 1 (BACE1) Proteins
beta-site APP cleaving enzyme 1 (Bace1) Proteins
beta-secretase 1 (Bace1) Proteins
beta-site APP-cleaving enzyme 1 (bace1) Proteins
ASP2 Proteins
BACE Proteins
Bace Proteins
BACE1 Proteins
C76936 Proteins
HSPC104 Proteins
MGC145931 Proteins
zgc:77409 Proteins
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