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CREB3L3 encodes a member of the basic-leucine zipper family and the AMP-dependent transcription factor family. Additionally we are shipping CREB3L3 Antibodies (18) and many more products for this protein.
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Beta-TrCP (show BTRC Proteins) controls ubiquitination and degradation of liver-enriched transcription factor CREB-H.
Identify a novel pathogenic mutation in CREB3L3 gene in a family with dominant hypertriglyceridemia with a variable pattern of penetrance.
CREBH activated by HBx interacted with HBx protein, leading to a synergistic effect on the expression of AP-1 (show FOSB Proteins) target genes and the proliferation of hepatocellular carcinoma cells and mouse primary hepatocytes.
Taken together, our results demonstrated that human APOA5 (show APOA5 Proteins) is directly regulated by CREBH via CREBHRE and provided a new insight into the role of this liver-specific bZIP transcription factor in lipoprotein metabolism and triglyceride homeostasis
Studies indicate that mutations in CREB3L3 in individuals with extreme hypertriglyceridemia.
a novel mechanism of action of activated CB1R (show CNR1 Proteins) signaling to induce hepatic gluconeogenesis via direct activation of CREBH
Levels of CREB (show CREB1 Proteins) transcripts did NOT significantly differ in the thyroid adenomas and surrounding normal tissues.
analysis of CREB-H trafficking into alternate pathways of ERAD and stress-regulated intramembrane proteolysis
findings show that CREBH an endoplasmic reti (show HAMP Proteins)culum stress-activa (show HAMP Proteins)ted transcription factor, binds to and transactivates the hepcidin promoter
fasting or glucagon (show GCG Proteins) stimulation modulates lipid homeostasis through acetylation of CREBH.
Overexpression of nuclear CREB3L3 induced systemic lipolysis, hepatic ketogenesis, and insulin (show INS Proteins) sensitivity with increased energy expenditure.
CREBH-Fsp27beta axis is important for regulating lipid droplet dynamics and triglyceride storage in the liver
CREBH activated by HBx interacted with HBx protein, leading to a synergistic effect on the expression of AP-1 (show JUN Proteins) target genes and the proliferation of hepatocellular carcinoma cells and mouse primary hepatocytes.
Alpha lipoic acid (ALA) increases hepatic FGF21 (show FGF21 Proteins) expression via up-regulation of CREBH, identifying ALA as a novel positive regulator of FGF21 (show FGF21 Proteins)
Orphan nuclear receptor (show NR1D1 Proteins) Errgamma (show ESRRG Proteins) induces C-reactive protein (show CRP Proteins) gene expression through induction of ER-bound Bzip transmembrane transcription factor CREBH.
analysis of the transcriptional regulatory axis of CREBH-PPARalpha (show PPARA Proteins)-FGF21 (show FGF21 Proteins) that has a role in maintaining lipid homeostasis under metabolic stress
These data demonstrate that CREBH is a positive regulator of CYP2B in response to sulpyrine administration, which possibly results in fatal shock.
Data indicate that knockdown of Crebh or Cb1r (show CNR1 Proteins) antagonism attenuated 2-arachidonoylglycerol mediated induction of Lipin1 (show LPIN1 Proteins) gene expression and decreased diacylglycerol production in liver and subsequently restored insulin receptor (show INSR Proteins) signaling.
Studies indicate that CREB-H-deficient mice showed hypertriglyceridemia.
This gene encodes a member of the basic-leucine zipper family and the AMP-dependent transcription factor family. The encoded protein is localized to the endoplasmic reticulum and acts as a transcription factor activated by cyclic AMP stimulation. The encoded protein binds the cyclic AMP response element (CRE) and the box-B element and has been linked to acute inflammatory response, hepatocellular carcinoma, triglyceride metabolism, and hepcidin expression. Alternative splicing results in multiple transcript variants.
CREB/ATF family transcription factor
, cyclic AMP-responsive element-binding protein 3-like protein 3
, cAMP-responsive element-binding protein 3-like protein 3
, transcription factor CREB-H
, cAMP-responsive element-binding protein 3-like protein 3-A
, cAMP-responsive element-binding protein 3-like protein 3-B
, cyclic AMP-responsive element-binding protein 3-like protein 3-A
, cyclic AMP-responsive element-binding protein 3-like protein 3-B