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clathrin, Heavy Chain (Hc) (CLTC) ELISA Kits

Clathrin is a major protein component of the cytoplasmic face of intracellular organelles, called coated vesicles and coated pits. Additionally we are shipping clathrin, Heavy Chain (Hc) Antibodies (66) and and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human CLTC CLTC 1213 Q00610
Anti-Rat CLTC CLTC 54241 P11442
Anti-Mouse CLTC CLTC 67300 Q68FD5
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More ELISA Kits for clathrin, Heavy Chain (Hc) Interaction Partners

Caenorhabditis elegans (C. elegans) clathrin, Heavy Chain (Hc) (CLTC) interaction partners

  1. The clathrin heavy chain CHC-1 negatively regulates pulling forces acting on centrosomes during interphase and on spindle poles during mitosis in one-cell C. elegans embryos.

  2. Inactivating epn-1 (show EPN1 ELISA Kits) or chc-1 disrupts engulfment by impairing actin polymerization. CHC-1 is enriched on extending pseudopods together with EPN-1 (show EPN1 ELISA Kits), in an EPN-1 (show EPN1 ELISA Kits)-dependent manner.

  3. These results indicate that a high level of CHC activity is required for receptor-mediated endocytosis in nonneuronal cells but is largely dispensable for maintenance of synaptic vesicle pools.

  4. Loss of SNX-1 (show SNX1 ELISA Kits), RME-8, or the clathrin chaperone Hsc70 (show HSPA8 ELISA Kits)/HSP-1 leads to over-accumulation of endosomal clathrin, reduced clathrin dynamics, and missorting of MIG-14 (show RAE1 ELISA Kits) to the lysosome.

Arabidopsis thaliana clathrin, Heavy Chain (Hc) (CLTC) interaction partners

  1. Data indicate that MTV1 (AT3G16270) and AGD5 (AT5G54310) Physically Interact with clathrin.

  2. study presents a genetic characterization of the role of clathrin in endocytosis and auxin-mediated plant development; data demonstrate a fundamental role for clathrin function in cell polarity, growth, patterning, and organogenesis

Pig (Porcine) clathrin, Heavy Chain (Hc) (CLTC) interaction partners

  1. Taken together, these results demonstrate that Japanese encephalitis virus enters porcine kidney epithelial PK15 cells through cholesterol- and clathrin-mediated endocytosis.

  2. Clathrin plays a crucial role in meiotic spindle function in maturing oocytes, possibly through spindle stabilization

Human clathrin, Heavy Chain (Hc) (CLTC) interaction partners

  1. Data indicate that clathrin-mediated endocytosis of proto-oncogene (show RAB1A ELISA Kits) protein erbB-3 (ErbB3 (show ERBB3 ELISA Kits)) is depending on epsin-1 (show EPN1 ELISA Kits).

  2. SMAP2 (show BRD8 ELISA Kits) immunoprecipitated clathrin and AP-1 (show FOSB ELISA Kits) through a putative clathrin-binding domain and a CALM-binding domain, and SMAP2 (show BRD8 ELISA Kits) mutants that did not interact with clathrin or AP-1 (show FOSB ELISA Kits) could not localize to recycling endosomes

  3. autophagy contributed to Cx31.1 (show GJB5 ELISA Kits) degradation, and clathrin might be involved in the autophagy of Cx31.1 (show GJB5 ELISA Kits).

  4. Data suggest that by binding to both clathrin and F-actin, mammalian actin-binding protein 1 (mAbp1 (show DBNL ELISA Kits); HIP-55 (show DBNL ELISA Kits) or SH3P7 (show DBNL ELISA Kits)) is specifically recruited at a late stage of clathrin-coated pits (CCPs) formation, which subsequently recruits dynamin (show DNM1 ELISA Kits) to CCPs.

  5. In conclusion these data suggest that Streptococcus pneumoniae PspC-promoted uptake via the polymeric immunoglobulin receptor of epithelial cells is mediated by both clathrin and caveolin dependent pathway.

  6. Our data support a model in which nascent Hepatits C Virus particles associate with apoE in the endoplasmic reticulum and exit cells following a clathrin-dependent transendosomal secretory route.

  7. clathrin-mediated and caveolae-mediated endocytosis of VE-cad (show CDH5 ELISA Kits) contribute to lipopolysaccharide-induced vascular hyperpermeability.

  8. These data indicate that clathrin is required for the function of AP-1 (show FOSB ELISA Kits)- and GGA-coated carriers at the trans-Golgi network but may be dispensable for outward traffic en route to the plasma membrane.

  9. Clathrin and caveolin-1 (show CAV1 ELISA Kits) have a role in docking of SMAD4 (show SMAD4 ELISA Kits) at the cell membrane.

  10. SNX9 (show SNX9 ELISA Kits) and CHC function in the same molecular pathway for chromosome alignment and segregation, which is dependent on their direct association.

Cow (Bovine) clathrin, Heavy Chain (Hc) (CLTC) interaction partners

  1. three different clathrin-box motif peptides can each simultaneously bind not only to the previously characterized clathrin-box site but also to the W-box site and the beta-arrestin splice loop site on a single TD.

  2. Structure of clathrin coat with bound Hsc70 (show HSPA8 ELISA Kits) and auxilin (show DNAJC6 ELISA Kits).

  3. clathrin-FKBP36-Hsp72 complexes resulting from both identified interactions are bound to the matrices of clathrin-coated vesicles in spermatocytes, which indicates a possible role of FKBP36 and Hsp72 in the disassembly of clathrin coats

Mouse (Murine) clathrin, Heavy Chain (Hc) (CLTC) interaction partners

  1. PTEN-like domains of GAK and auxilin are not essential for Hsc70-dependent chaperoning and uncoating of clathrin, but depending on the tissue, these domains appear to increase the efficiency of these co-chaperones.

  2. The clathrin-mediated endocytic machinery combines with Dab2 (show DAB2 ELISA Kits) to facilitate the endocytosis of RGD-integrin-beta3 clusters.

  3. Taken together, these results show that CLTC plays an important role in spindle assembly and chromosome congression through a microtubule correlation mechanism during mouse oocyte maturation.

  4. Auditory inner hair cells use dynamin-dependent endocytosis via clathrin-mediated endocytosis.

  5. Data indicate that dynamin (show DNM1 ELISA Kits), clathrin, adaptor protein complex-2 (AP2 (show TFAP2A ELISA Kits)), and amphiphysin (show AMPH ELISA Kits) contribute to the depolarization-evoked entry in endocytosis.

  6. This study reveals a novel functional role of clathrin-coated structure in GMR (show CSF2RA ELISA Kits) signaling and the oncogenesis of JAK2V617F.

  7. The authors report that Dab2, previously described as an inhibitor of Wnt/beta-catenin signalling, selectively recruits LRP6 to the clathrin-dependent endocytic route, thereby sequestering it from caveolin-mediated endocytosis.

  8. Microtubule associated protein 1B (show MAP1B ELISA Kits), a microtubule stabilizing protein, and clathrin heavy chain, the major component of the clathrin triskelion, were identified as interaction partners for dystonin (show DST ELISA Kits)-a

  9. neither clathrin nor AP-2 (show TFAP2A ELISA Kits) is essential for the internalization of epidermal growth factor (show EGF ELISA Kits)

  10. A1AT (show SERPINA1 ELISA Kits) associated with clathrin heavy chains, but not with caveolin-1 (show CAV1 ELISA Kits) in the plasma membrane fraction of endothelial cells.

clathrin, Heavy Chain (Hc) (CLTC) Antigen Profile

Antigen Summary

Clathrin is a major protein component of the cytoplasmic face of intracellular organelles, called coated vesicles and coated pits. These specialized organelles are involved in the intracellular trafficking of receptors and endocytosis of a variety of macromolecules. The basic subunit of the clathrin coat is composed of three heavy chains and three light chains.

Gene names and symbols associated with CLTC

  • Clathrin Heavy Chain (chc-1) antibody
  • clathrin, heavy chain (Hc) (CLTC) antibody
  • clathrin heavy chain 1 (CNJ03270) antibody
  • clathrin heavy chain (cgd8_1270) antibody
  • clathrin heavy chain (TP03_0480) antibody
  • clathrin heavy chain (Tc00.1047053506167.50) antibody
  • clathrin heavy chain 1 (ATEG_05434) antibody
  • clathrin heavy chain (AaeL_AAEL013614) antibody
  • clathrin heavy chain (LmjF36.1630) antibody
  • clathrin heavy chain (CHC1) antibody
  • clathrin heavy chain (CpipJ_CPIJ014882) antibody
  • clathrin heavy chain 1 (CMU_025200) antibody
  • clathrin heavy chain (PMAA_094250) antibody
  • clathrin heavy chain 1 (SJAG_02282) antibody
  • clathrin heavy chain (CHC) antibody
  • clathrin heavy chain (Smp_154420.1) antibody
  • clathrin heavy chain 1 (PAAG_00730) antibody
  • clathrin heavy chain (MCYG_06136) antibody
  • clathrin heavy chain 1 (VDBG_05048) antibody
  • clathrin heavy chain 1 (MGYG_04658) antibody
  • clathrin heavy chain (Chc) antibody
  • Clathrin, heavy chain (AT3G11130) antibody
  • clathrin, heavy chain (Hc) (Cltc) antibody
  • clathrin, heavy polypeptide (Hc) (Cltc) antibody
  • 3110065L21Rik antibody
  • Chc antibody
  • CHC17 antibody
  • CLH-17 antibody
  • CLTC antibody
  • CLTCL2 antibody
  • F11B9.30 antibody
  • Hc antibody
  • R74732 antibody

Protein level used designations for CLTC

Clathrin Heavy Chain family member (chc-1) , clathrin heavy chain 1 , clathrin heavy-chain , clathrin, heavy polypeptide (Hc) , clathrin, heavy chain (Hc) , clathrin heavy chain , clathrin heavy chain on chromosome 17 , clathrin, heavy polypeptide-like 2

GENE ID SPECIES
176434 Caenorhabditis elegans
395272 Gallus gallus
455168 Pan troglodytes
480578 Canis lupus familiaris
3254223 Cryptococcus neoformans var. neoformans JEC21
3374266 Cryptosporidium parvum Iowa II
3499985 Theileria parva strain Muguga
3540437 Trypanosoma cruzi strain CL Brener
4320947 Aspergillus terreus NIH2624
5578293 Aedes aegypti
5655418 Leishmania major strain Friedlin
5725357 Chlamydomonas reinhardtii
6047964 Culex quinquefasciatus
6995013 Cryptosporidium muris RN66
7026543 Talaromyces marneffei ATCC 18224
7049029 Schizosaccharomyces japonicus yFS275
7449343 Thalassiosira pseudonana CCMP1335
8340532 Schistosoma mansoni
9100448 Paracoccidioides sp. 'lutzii' Pb01
9227238 Arthroderma otae CBS 113480
9532124 Verticillium alfalfae VaMs.102
10027332 Arthroderma gypseum CBS 118893
100228172 Taeniopygia guttata
100233163 Bombyx mori
820284 Arabidopsis thaliana
100271929 Sus scrofa
1213 Homo sapiens
54241 Rattus norvegicus
281080 Bos taurus
67300 Mus musculus
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