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The enzyme encoded by GGT1 catalyzes the transfer of the glutamyl moiety of glutathione to a variety of amino acids and dipeptide acceptors. Additionally we are shipping gamma Glutamyltransferase 1 Kits (54) and gamma Glutamyltransferase 1 Proteins (17) and many more products for this protein.
Showing 10 out of 135 products:
Human Polyclonal GGT1 Primary Antibody for WB - ABIN1881373
Ikeda, Maki, Yin, Kawate, Adachi, Ohnaka, Takayanagi, Kono: Relation of coffee consumption and serum liver enzymes in Japanese men and women with reference to effect modification of alcohol use and body mass index. in Scandinavian journal of clinical and laboratory investigation 2010
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Human Monoclonal GGT1 Primary Antibody for IHC (p), IP - ABIN561038
West, Segu, Feasley, Kang, Klouckova, Li, Novotny, West, Mechref, Hanigan: Analysis of site-specific glycosylation of renal and hepatic ?-glutamyl transpeptidase from normal human tissue. in The Journal of biological chemistry 2010
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Mouse (Murine) Polyclonal GGT1 Primary Antibody for WB - ABIN1881372
Aly, Lightfoot, El-Shemy: Modulatory role of lipoic acid on lipopolysaccharide-induced oxidative stress in adult rat Sertoli cells in vitro. in Chemico-biological interactions 2009
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Human Monoclonal GGT1 Primary Antibody for FACS, IHC (fro) - ABIN180610
Knoll, Wrasidlo, Scherberich, Gaedicke, Fischer: Targeted therapy of experimental renal cell carcinoma with a novel conjugate of monoclonal antibody 138H11 and calicheamicin thetaI1. in Cancer research 2000
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gamma-glutamyltransferase may have a role in nasopharyngeal carcinoma
Formation of LTD4 was rapid when catalyzed by gamma-glutamyl transpeptidase (GGT)1 in the A549 epithelial lung cancer cell line, but considerably slower when catalyzed by GGT5 (show GGT5 Antibodies) in primary bronchial epithelial cells. When A549 cells were cultured in the presence of IL-1beta (show IL1B Antibodies), GGT1 expression increased about 2-fold. Also exosomes from A549 cells contained GGT1 and augmented LTD4 formation.
Results show a weak genetic evidence that GGT levels may have a causal role in the development of type 2 diabetes.
The structure of DON-bound hGGT1 has led to the discovery of a new mechanism of inactivation by DON that differs from its inactivation of other glutamine (show GFPT1 Antibodies) metabolizing enzymes, and insight into the activation of the catalytic nucleophile that initiates the hGGT1 reaction.
Study demonstrated that the combined effect of serum GGT and uric acid is associated with a diabetes risk in Korean women and that the use of the measurements of a combination of GGT and uric acid appears to have an additional benefit in the prediction of the future development of diabetes
Impaired GGT expression has the potential to become a valuable tool for stratifying endometrioid adenocarcinoma of the uterus patients' prognosis and treatment planning
evaluation of the association of gamma-glutamyl transpeptidase to platelet ratio with liver fibrosis in chronic hepatitis C patients should take diabetes status into consideration.
In patients with coronary artery disease, elevated gamma-glutamyltransferase activity is independently associated with the presence of atrial fibrillation.
Specific gene polymorphisms are known to be associated with a different arterial physiology in the younger generation. The present study found that young Russians with the matrix metalloproteinase 3 6A/6A and gamma-glutamyltransferase 1AA genotypes have lower levels of the cardio-ankle vascular index - a recent measure of arterial stiffness.
Preoperative GGT can serve as an independent prognostic biomarker of nonmetastatic renal cell carcinoma (show MOK Antibodies) patients with venous tumor thrombus.
Statins can significantly decrease the expression of GGT in aortic atherosclerotic plaques of ApoE (show APOE Antibodies)-knockout mice.
Gamma-glutamyltransferase levels are an independent predictor of worsening kidney function and mortality in acute heart failure patients.
Disruption of the Mrds1/Ofcc1 gene elicits asymptomatic hyper-gamma-glutamyl-transpeptidasemia in mice.
Mutations in the Ggt1 gene are responsible for the phenotypes of dwg/dwg and dwg(Bayer)/dwg(Bayer) mice.
prooxidant reactions mediated by gamma-GT in turn regulate the levels of tyrosinase (show TYR Antibodies) in pigment cells.
GGT regulates osteoclast biology at least partly independently of sex steroids
GGT stimulates RANKL (show TNFSF11 Antibodies) expression
GGT is implicated as being involved in diseases characterized by accelerated osteoclast development and bone destruction.
This gene encodes a member of the gamma-glutamyl transpeptidase (GGT) family, which are important in the metabolism of glutathione. The most ubiquitously expressed human GGT gene, GGT1, encodes a single transmembrane polypeptide that is post-translationally processed to form a heavy and a light chain. In contrast, the product of this gene only contains homology to the light chain region, and lacks a transmembrane domain. Multiple alternatively spliced variants, encoding the same protein, have been identified.
, gamma-glutamyltranspeptidase 1
, gamma-glutamyl transpeptidase
, ggt 1
, gamma-glutamyltransferase 1 a
, Gamma-glutamyltranspeptidase 1
, gamma-glutamyltranspeptidase 1-like
, glutamyl transpeptidase
, glutathione hydrolase 1
, leukotriene-C4 hydrolase
, GGT 1
, gamma glutamyl-transferase 1
, gamma-glutamyltransferase 2
, gamma-glutamyltransferase-like activity 3
, gamma-glutamyltransferase-like activity 4
, gamma-glutamyltransferase-like protein 6