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anti-gamma-Glutamyl Carboxylase (GGCX) Antibodies

GGCX encodes an enzyme which catalyzes the posttranslational modification of vitamin K-dependent protein. Additionally we are shipping GGCX Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
GGCX 2677 P38435
GGCX 56316 Q9QYC7
GGCX 81716 O88496
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Top anti-GGCX Antibodies at antibodies-online.com

Showing 10 out of 63 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-GGCX Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: MCF7 cell lysate Host: Rabbit  Target Name: GGCX  Sample Tissue: Jurkat  Antibody Dilution: 1.0 µg/mL GGCX is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p), WB GGCX Antibody (Center) (ABIN655069) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Formalin fixed and paraffin embedded human liver tissue reacted with GGCX Antibody (Center) followed by peroxidase conjugation of the secondary antibody and DAB staining. Western blot analysis of GGCX Antibody (Center) in 293 cell line lysates (35ug/lane). This demonstrates the GGCX antibody detected the GGCX protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Dog Goat Un-conjugated EIA, WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Goat Un-conjugated IHC (p), ELISA, WB Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated WB GGCX antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 3 to 4 Days
$473.93
Details
Human Rabbit Un-conjugated IP, ELISA, WB   100 μg Log in to see 1 to 2 Days
$485.57
Details

GGCX Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-GGCX Antibodies

  1. Human Polyclonal GGCX Primary Antibody for EIA, IHC (p) - ABIN952508 : Higgins-Gruber, Mutucumarana, Lin, Jorgenson, Stafford, Straight: Effect of vitamin K-dependent protein precursor propeptide, vitamin K hydroquinone, and glutamate substrate binding on the structure and function of {gamma}-glutamyl carboxylase. in The Journal of biological chemistry 2010 (PubMed)
    Show all 5 references for ABIN952508

  2. Cow (Bovine) Polyclonal GGCX Primary Antibody for IHC, WB - ABIN2781826 : Rieder, Reiner, Rettie: Gamma-glutamyl carboxylase (GGCX) tagSNPs have limited utility for predicting warfarin maintenance dose. in Journal of thrombosis and haemostasis : JTH 2007 (PubMed)

  3. Dog (Canine) Polyclonal GGCX Primary Antibody for EIA, WB - ABIN452673 : Li, Grange, Armstrong, Whelan, Hurley, Rishavy, Hallgren, Berkner, Schurgers, Jiang, Uitto: Mutations in the GGCX and ABCC6 genes in a family with pseudoxanthoma elasticum-like phenotypes. in The Journal of investigative dermatology 2009 (PubMed)

More Antibodies against GGCX Interaction Partners

Human gamma-Glutamyl Carboxylase (GGCX) interaction partners

  1. GGCX c.2084+45G polymorphisms has a moderate effect on VKAs dose requirements in Slavic population from Central-Eastern Europe.

  2. Detected are ten mutations in the gamma-glutamyl carboxylase gene in patients with hereditary deficiency of vitamin K-dependent coagulation factors.

  3. The allele frequency for GGCX 12970 C > G is 1.43 in north Indians and did not have a significant bearing on the maintenance dose of acenocoumarol oral anticoagulant in cardiac valve replacement patients.

  4. GGCX mutation found in families with pseudoxanthoma elasticum with retinitis pigmentosa and cutis laxa.

  5. These findings indicate that individuals carrying the CYP2C19 (show CYP2C19 Antibodies) rs3814637CC or CYP2C9 (show CYP2C9 Antibodies) rs1057910AA or GGCX rs699664AA genotype needed higher warfarin doses in the Chinese population.

  6. In atrial fibrillation population in Xinjiang, patients with CT and TT genotypes in the gamma-glutamyl carboxylase gene rs259251 loci required significantly higher warfarin dose than those with CC genotype.

  7. evaluation of urinary Gla (show NAT8 Antibodies) excretion in relation with apo E (show APOE Antibodies) genotype

  8. study demonstrated the effects of SNP (974G>A) in the GGCX gene on the correlation between dietary vitamin K intake and gamma-carboxylation of serum osteocalcin (show BGLAP Antibodies)

  9. there may be no significant association between the low activity and mutation of GGCX in calcium oxalate urolithiasis

  10. Quantitative PCR assays for VKORC1 (show VKORC1 Antibodies), CYP4F2 (show CYP4F2 Antibodies), GGCX and CALU (show CALU Antibodies) identified two copies in all populations.

Mouse (Murine) gamma-Glutamyl Carboxylase (GGCX) interaction partners

  1. GGCX in osteoblasts functions to prevent abnormal mineralization in bone formation.

  2. findings suggest that GGCX expressed in osteoblasts is critical for the maintenance of blood glucose and WAT

  3. OCN is gamma-carboxylated by the gamma-carboxylase (GGCX) on three glutamic acid residues, a cellular process requiring reduction of vitamin K by a second enzyme, VKORC1 (show VKORC1 Antibodies).

  4. Ggcx(Deltaliver/Deltaliver) mice displayed bleeding diathesis.

  5. Effect of vitamin K-dependent protein precursor propeptide, vitamin K hydroquinone, and glutamate (show GRIN1 Antibodies) substrate binding on the structure and function of {gamma}-glutamyl carboxylase.

  6. These findings suggest a role for both the GGCX gene and the genetic background as well as dietary factors in modulating the phenotypic severity of Pseudoxanthoma elasticum caused by loss-of-function mutations in ABCC6 (show ABCC6 Antibodies).

  7. Analysis of a Ggcx(+/-) intercross revealed a partial developmental block with only 50% of expected Ggcx(-/-) offspring surviving to term, with the latter animals dying uniformly at birth of massive intra-abdominal hemorrhage

GGCX Antigen Profile

Protein Summary

This gene encodes an enzyme which catalyzes the posttranslational modification of vitamin K-dependent protein. Many of these vitamin K-dependent proteins are involved in coagulation so the function of the encoded enzyme is essential for hemostasis. Mutations in this gene are associated with vitamin K-dependent coagulation defect and PXE-like disorder with multiple coagulation factor deficiency. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with GGCX

  • gamma-glutamyl carboxylase (GGCX) antibody
  • gamma-glutamyl carboxylase (ggcx) antibody
  • gamma-glutamyl carboxylase (GC) antibody
  • gamma-glutamyl carboxylase (sce5891) antibody
  • gamma-glutamyl carboxylase (Ggcx) antibody
  • cb751 antibody
  • CG13927 antibody
  • dgammaC antibody
  • dGC antibody
  • Dmel\\CG13927 antibody
  • gammaC antibody
  • GGC antibody
  • ggcx antibody
  • si:ch1073-230p18.3 antibody
  • VKCFD1 antibody
  • zgc:158736 antibody

Protein level used designations for GGCX

gamma-glutamyl carboxylase , vitamin K-dependent gamma-carboxylase , peptidyl-glutamate 4-carboxylase , vitamin K gamma glutamyl carboxylase , CG13927-PA , CG13927-PB , GC-PA , GC-PB , gamma-glutamyl-carboxylase , gamma glutamyl carboxylase

GENE ID SPECIES
459364 Pan troglodytes
557240 Danio rerio
695628 Macaca mulatta
780874 Ciona intestinalis
100144666 Xenopus (Silurana) tropicalis
100171564 Pongo abelii
38194 Drosophila melanogaster
5810488 Sorangium cellulosum So ce56
444473 Xenopus laevis
2677 Homo sapiens
281190 Bos taurus
56316 Mus musculus
81716 Rattus norvegicus
475769 Canis lupus familiaris
443129 Ovis aries
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