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GGH catalyzes the hydrolysis of folylpoly-gamma-glutamates and antifolylpoly-gamma-glutamates by the removal of gamma-linked polyglutamates and glutamate. Additionally we are shipping gamma-Glutamyl Hydrolase (Conjugase, Folylpolygammaglutamyl Hydrolase) Kits (8) and gamma-Glutamyl Hydrolase (Conjugase, Folylpolygammaglutamyl Hydrolase) Proteins (8) and many more products for this protein.
Showing 10 out of 58 products:
Human Polyclonal GGH Primary Antibody for EIA, FACS - ABIN952457
Adjei, Salavaggione, Mandrekar, Dy, Ziegler, Endo, Molina, Schild, Adjei: Correlation between polymorphisms of the reduced folate carrier gene (SLC19A1) and survival after pemetrexed-based therapy in non-small cell lung cancer: a North Central Cancer Treatment Group-based exploratory study. in Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2010
Show all 4 references for ABIN952457
Human Polyclonal GGH Primary Antibody for EIA, IF - ABIN952456
Organista-Nava, Gómez-Gómez, Saavedra-Herrera, Rivera-Ramírez, Terán-Porcayo, Alarcón-Romero, Illades-Aguiar, Leyva-Vázquez: Polymorphisms of the gamma-glutamyl hydrolase gene and risk of relapse to acute lymphoblastic leukemia in Mexico. in Leukemia research 2010
Show all 4 references for ABIN952456
Human Polyclonal GGH Primary Antibody for FACS, IF - ABIN655984
Liu, Wu, Chen, Ter-Minassian, Asomaning, Zhai, Wang, Su, Heist, Kulke, Lin, Liu, Christiani: A Large-scale genetic association study of esophageal adenocarcinoma risk. in Carcinogenesis 2010
Human Polyclonal GGH Primary Antibody for ELISA, WB - ABIN1534924
Yin, Chave, Macaluso, Galivan, Yao: Structural organization of the human gamma-glutamyl hydrolase gene. in Gene 1999
These results indicate that elevated expressions of the tumor-related genes FPGS/GGH and VEGF are correlated with malignancy of thymic carcinoma and B3 thymoma tumors.
There were no other associations between single -nucleotide polymorphisms and the efficacy of MTX (show MTX1 Antibodies) treatment. CONCLUSIONS: The MTHFR (show MTHFR Antibodies) 677CC and GGH 401TT and CT genotypes were associated with a reduction in the number of MTX (show MTX1 Antibodies)-related adverse events.
the highest expression of GGH and EGFR (show EGFR Antibodies) was noted in the left-sided colon; the highest expression of DHFR (show DHFR Antibodies), FPGS (show FPGS Antibodies), TOP1 (show TOP1 Antibodies) and ERCC1 (show ERCC1 Antibodies) was noted in the rectosigmoid, whereas TYMP (show TYMP Antibodies) expression was approximately equivalent in the right-sided colon and rectum
This study shows that polymorphisms on genes related to the metabolic pathway of pemetrexed, especially, ATIC (show ATIC Antibodies) and GGH genes, would have a therapeutic implication in pemetrexed-treated patients with lung adenocarcinoma
Polymorphism of GGH rs3758149 C>T is associated with response to therapy in acute lymphoblastic leukemia.
An interaction term, between FPGS (show FPGS Antibodies) rs7033913 heterozygotes and GGH rs11988534 homozygotes for the minor allele, had a p-value <0.0001 and may contribute to metotrexate toxicity in rheumatoid arthritis.
GG genotype of GGH -354 T > G polymorphism may have high predictive value for myelosuppression in methotrexate treated rheumatoid arthritis patients.
Suggest that GGH may serve as a potential biomarker of unfavorable clinical outcomes over short-term follow-up in breast cancer.
Genotyping of DHFR 829C>T and GGH -401C>T was performed using a polymerase chain reaction.
The results of our study suggested the potential interest of GGH -401C>T as a predictive factor of the outcome of cervical carcinoma treated with cisplatin-based chemoradiotherapy.
This gene catalyzes the hydrolysis of folylpoly-gamma-glutamates and antifolylpoly-gamma-glutamates by the removal of gamma-linked polyglutamates and glutamate.
, gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
, folylpolyglutamate hydrolase
, gamma-Glu-x carboxypeptidase
, gamma-Glu-X carboxypeptidase