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gamma-aminobutyric Acid (GABA) A Receptor, alpha 5 Proteins (GABRA5)

GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Additionally we are shipping GABRA5 Antibodies (59) and GABRA5 Kits (1) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat GABRA5 GABRA5 29707 P19969
GABRA5 2558 P31644
GABRA5 110886 Q8BHJ7
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Top GABRA5 Proteins at antibodies-online.com

Showing 6 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

GABRA5 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
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Mouse (Murine) ,
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More Proteins for gamma-aminobutyric Acid (GABA) A Receptor, alpha 5 (GABRA5) Interaction Partners

Rhesus Monkey gamma-aminobutyric Acid (GABA) A Receptor, alpha 5 (GABRA5) interaction partners

  1. GABRA5 receptor plays a unique role in reinforcing the effects of alcohol.

  2. evaluated the role of alpha1 and alpha5 subunit-containing GABAA (show GABRg1 Proteins) receptors (alpha1GABAA and alpha5GABAA receptors, respectively) in the ability of benzodiazepine-type drugs to alter performance in the cognitive domain of executive function

Human gamma-aminobutyric Acid (GABA) A Receptor, alpha 5 (GABRA5) interaction partners

  1. Report benzodiazepine derivative as GABA-site inhibitor of extra-synaptic GABAA (show GABRg1 Proteins) alpha5 receptors.

  2. Study found that a significant portion of GABAergic postsynaptic compartments contain the alpha5 GABAAR (show GABRG2 Proteins) subunit, both in vitro and in vivo

  3. This study showed that in male groups, the expression of GABRA5 was generally lower in schizophrenia cases compared to the control.

  4. Findings provide genetic evidence for the involvement of the genes GABRB3 (show GABRB3 Proteins) and GABRA5 in the susceptibility to panic disorder

  5. 1,2-dichlorohexafluorocyclobutane enhancement of GABRA5 activity is abolished by GABRB3 (show GABRB3 Proteins) mutations.

  6. These results provide initial evidence of a GABAA (show GABRg1 Proteins) alpha5 deficit in autism spectrum disorder and support further investigations of the GABA system in this disorder.

  7. The ratios of beta(3)/beta(2) and alpha(5)/alpha(1) subunit protein expression in Angelman syndrome (show ube3a Proteins) cortex were significantly decreased when compared with controls.

  8. These results suggest that the GABRA5 gene may confer susceptibility to bipolar I disorder.

Mouse (Murine) gamma-aminobutyric Acid (GABA) A Receptor, alpha 5 (GABRA5) interaction partners

  1. Report benzodiazepine derivative as GABA-site inhibitor of extra-synaptic GABAA (show GABRg1 Proteins) alpha5 receptors.

  2. This study demonstrated that alpha5-GABAAR (show GABRG2 Proteins)-mediated tonic inhibition in the DG plays an important role in ensuring normal cognitive functioning under high-interference memory conditions.

  3. The results of this study suggested that gabra5 mediated tonic current, which is potentiated by H2O2, might contribute to H2O2-induced brain dysfunction.

  4. in mice that lack the alpha5 subunit gene (Gabra5-/-), cultured embryonic hippocampal pyramidal neurons and ex vivo CA1 (show CA1 Proteins) hippocampal neurons unexpectedly exhibited a decrease in Ih current density

  5. Gabra5-gene haplotype block associated with behavioral properties of the full agonist benzodiazepine chlordiazepoxide.

  6. Data suggest that chronic exposure to ketamine impairs working memory in mice, which may be explained at least partly by up-regulation of Gabra5 subunits in the prefrontal cortex.

  7. Depending on cell type, Gabra5 and delta subunits are the principal GABA A receptor subunits regulating tonic inhibition in hippocampal neurons.

GABRA5 Protein Profile

Protein Summary

GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Transcript variants utilizing three different alternative non-coding first exons have been described.

Gene names and symbols associated with GABRA5

  • gamma-aminobutyric acid (GABA) A receptor, alpha 5 (GABRA5)
  • gamma-aminobutyric acid (GABA) A receptor, alpha 5 (gabra5)
  • gamma-aminobutyric acid (GABA) A receptor, alpha 5 (Gabra5)
  • gamma-aminobutyric acid (GABA) A receptor, subunit alpha 5 (Gabra5)
  • gamma-aminobutyric acid A receptor subunit alpha-5 (gabra5)
  • A230018I05Rik protein
  • GABRA5 protein
  • si:dkey-93p24.1 protein

Protein level used designations for GABRA5

gamma-aminobutyric acid (GABA) A receptor, alpha 5 , gamma-aminobutyric acid A receptor, alpha 5-like , gamma-aminobutyric acid receptor subunit alpha-5-like , GABA(A) receptor subunit alpha-5 , GABA-A receptor alpha-5 subunit , gamma-aminobutyric acid A receptor, alpha 5 , gamma-aminobutyric acid (GABA-A) receptor, subunit alpha 5 , gamma-aminobutyric acid A receptor, alpha 5 , gamma-aminobutyric acid receptor subunit alpha-5 , GABAA receptor alpha5 subunit , ligand-gated ion channel subunit

GENE ID SPECIES
711838 Macaca mulatta
744855 Pan troglodytes
100340943 Oryctolagus cuniculus
100469857 Ailuropoda melanoleuca
100494208 Xenopus (Silurana) tropicalis
29707 Rattus norvegicus
799124 Danio rerio
418684 Gallus gallus
2558 Homo sapiens
488688 Canis lupus familiaris
523515 Bos taurus
110886 Mus musculus
100653497 Xenopus laevis
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