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gamma-aminobutyric Acid (GABA) B Receptor, 1 Proteins (GABBR1)

Gamma-aminobutyric acid (GABA) is the main inhibitory neurotransmitter in the mammalian central nervous system. Additionally we are shipping GABBR1 Antibodies (158) and GABBR1 Kits (4) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat GABBR1 GABBR1 81657 Q9Z0U4
GABBR1 2550 Q9UBS5
GABBR1 54393 Q9WV18
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Top GABBR1 Proteins at antibodies-online.com

Showing 7 out of 10 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 59 to 64 Days
$6,052.17
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 59 to 64 Days
$8,623.45
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
HOST_Wheat germ Human Un-conjugated   10 μg Log in to see 9 Days
$641.43
Details
HOST_Escherichia coli (E. coli) Streptococcus Un-conjugated   1 mg Log in to see 6 to 7 Days
$144.38
Details

GABBR1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine) ,
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More Proteins for gamma-aminobutyric Acid (GABA) B Receptor, 1 (GABBR1) Interaction Partners

Human gamma-aminobutyric Acid (GABA) B Receptor, 1 (GABBR1) interaction partners

  1. Results show that GABBR1 minor genotypes/alleles were protective against risk for alcoholism in 3 ethnically diverse cohorts.

  2. Cell surface ubiquitination precedes endocytosis, after which USP14 acts as an ubiquitin-binding protein that targets the ubiquitinated GABA B receptor to lysosomal degradation and promotes its deubiquitination.

  3. GABA(B)R stimulation promotes chemotaxis in RBL cells which is dependent on signaling via PI3-K/Akt, Src kinases and on rearrangement of both microtubules and actin cytoskeleton.

  4. GABBR1 receptors are expressed in aortic smooth muscle cells and regulate the [Ca(2 (show CA2 Proteins)+)]i via a Gi/o-coupled receptor pathway and a phospholipase C (show PLC Proteins) activation pathway.

  5. GABBR1 protein involved in phenylthiourea bitter taste detection.

  6. Authors suggest GABBR1, GABA receptor B1, is implicated in schizophrenia based on a Human endogenous retrovirus long terminal repeat (HERV-W LTR) in the regulatory region of GABBR1.

  7. GABA may inhibit the growth of cholangiocarcinoma QBC939 cells through the GABAB receptor, and the anti-cancer effects may be partly mediated via the JAK (show JAK3 Proteins)/STAT3 (show STAT3 Proteins) pathway

  8. Activation of GABA(B) receptors significantly inhibits Akt/GSK-3 signaling in a beta-arrestin-dependent pathway.

  9. We have discovered main triplets of amino acid residues in the GABAB1 receptor and several other neural receptors which seem to come from immunoglobulin chains and appear also as homologies in receptor heteromers.

  10. Long interval intracortical inhibition is significantly reduced and the cortical silent period is significantly shortened in patients with succinic semialdehyde dehydrogenase (SSADH (show ALDH5A1 Proteins)) deficiency compared to heterozygous parents and control groups.

Mouse (Murine) gamma-aminobutyric Acid (GABA) B Receptor, 1 (GABBR1) interaction partners

  1. These results suggest a role for GABAB receptor in Fmrp (show FMR1 Proteins) regulation and a potential interest of GABAB receptor signaling in Fragile X (show FMR1 Proteins) syndrome improvement.

  2. Activation of GABA(B) or mGlu2 (show GRM2 Proteins)/3 receptors inhibited both evoked presynaptic Ca(2 (show CA2 Proteins)+) transients and striatal field potentials.

  3. Immunoblotting and RT-PCR results showed that NIHL increased the expression of PKCgamma (show PRKCG Proteins) but decreased that of GABABR1 and GABABR2 (show GABBR2 Proteins) at both protein and mRNA levels in the CNC

  4. GABAB(1) receptor subunit isoforms differentially regulate the deleterious effects of stress and, thus, may be important therapeutic targets for the treatment of depression

  5. Results establish an endogenous GABA/GABAB1 feedback mechanism that keeps TRPV1 (show TRPV1 Proteins)-mediated pain hypersensitivity in check.

  6. The Gabbr1 has an important role in mediating the anxiety-related effects induced by nicotine.

  7. Sex differences in reproductive genes Gnrh1 (show GNRH1 Proteins), Gad1 (show GAD1 Proteins), and Kiss1 (show KISS1 Proteins) are critically disturbed in GABAB1-deficient mice, probably altering the organization and development of neural circuits governing the reproductive axis.

  8. GABAB signaling may normally directly or indirectly inhibit Kiss1 (show KISS1 Proteins) expression, particularly in the bed nucleus of the stria terminalis and medial amygdala

  9. Pharmacological inhibition of GABAB receptors stimulated neural stem cell proliferation and genetic deletion of GABAB1 receptor subunits increased neural stem cell proliferation and differentiation of neuroblasts in vivo.

  10. Enhanced GABA B receptor activity reduces expression of Arg3.1 (show Arc Proteins), which is critical for long-term memory.

GABBR1 Protein Profile

Protein Summary

Gamma-aminobutyric acid (GABA) is the main inhibitory neurotransmitter in the mammalian central nervous system. GABA exerts its effects through ionotropic

Gene names and symbols associated with GABBR1

  • gamma-aminobutyric acid (GABA) B receptor, 1a (gabbr1a)
  • gamma-aminobutyric acid (GABA) B receptor, 1 (GABBR1)
  • gamma-aminobutyric acid (GABA) B receptor, 1 (gabbr1)
  • gamma-aminobutyric acid (GABA) B receptor 1 (Gabbr1)
  • gamma-aminobutyric acid (GABA) B receptor, 1 (Gabbr1)
  • bM573K1.1 protein
  • dJ271M21.1.1 protein
  • dJ271M21.1.2 protein
  • GABA(B)R1 protein
  • GABAB1 protein
  • GABAbR1 protein
  • GABBR1 protein
  • GABBR1-3 protein
  • GB1 protein
  • GPRC3A protein

Protein level used designations for GABBR1

gamma-aminobutyric acid (GABA) B receptor, 1 , gaba1 , gamma-aminobutyric acid type B receptor subunit 1 , GABA-B receptor 1 , GABA-B-R1 , GABA-BR1 , GABABR1 , gb1 , GABAB, subunit 1c , seven transmembrane helix receptor , GABA-BR1b receptor , bM573K1.1.1 (gamma-aminobutyric acid (GABA) B receptor, 1a) , gamma-aminobutyric acid (GABA-B) receptor, 1 , gamma-aminobutyric acid (GABA) B receptor 1 , gamma-aminobutyric acid B receptor 1

GENE ID SPECIES
373873 Danio rerio
471946 Pan troglodytes
708987 Macaca mulatta
741043 Pan troglodytes
100135080 Xenopus (Silurana) tropicalis
100172928 Pongo abelii
81657 Rattus norvegicus
2550 Homo sapiens
54393 Mus musculus
513785 Bos taurus
488340 Canis lupus familiaris
100141417 Sus scrofa
100170763 Cavia porcellus
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