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gamma-aminobutyric Acid (GABA) A Receptor, gamma 2 Proteins (GABRG2)

GABRG2 encodes a gamma-aminobutyric acid (GABA) receptor. Additionally we are shipping GABRG2 Antibodies (112) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat GABRG2 GABRG2 29709 P18508
GABRG2 2566 P18507
GABRG2 14406 P22723
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Top GABRG2 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details

GABRG2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
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Mouse (Murine) ,
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More Proteins for gamma-aminobutyric Acid (GABA) A Receptor, gamma 2 (GABRG2) Interaction Partners

Human gamma-aminobutyric Acid (GABA) A Receptor, gamma 2 (GABRG2) interaction partners

  1. This review suggest that the pathogenesis of GABRG2 mutations is likely to be due to a combination of reduction of channel function and disturbance of cellular homeostasis due to the presence of mutant protein.

  2. Nova1 (show NOVA1 Proteins) interacts with GABAARgamma2 not only in the central nervous system but also in hepatocellular carcinoma. Nova1 (show NOVA1 Proteins)'s potential mechanism as an oncogene (show RAB1A Proteins) may due to its interaction with GABAA (show GABRg1 Proteins) Rgamma2.

  3. Thus, the presence of active GABA-A receptors, associated with phenotype determination via Ca(2 (show CA2 Proteins)+)-signalling was demonstrated in differentiating human DA neurons.

  4. common variants of GABRG2, RELN (show RELN Proteins) and NRG3 (show NRG3 Proteins) and the GABRG2-RELN (show RELN Proteins)-PTCH1 (show PTCH1 Proteins) interaction networks might confer altered susceptibility to Hirschsprung disease.

  5. GABRG2, in combination with GABRA4 (show GABRA4 Proteins), is associated with autism spectrum disorder in an Argentine dataset.

  6. Deletion of the N-terminal extension and putative alpha-helix in heteromeric alpha1beta2gamma2 GABAA (show GABRg1 Proteins) receptors in the gamma2 subunits reduced the number of functional receptors and incorporation into mature receptors.

  7. Mutant GABRG2 may be responsible for genetic epilepsy as well neurodegeneration.

  8. Mutations of the GABRG2 gene may increase the risk of rolandic epilepsy.

  9. This study demonistrated that epilepsy-associated mutations N79S, R82Q and P83S disrupted GABAA (show GABRg1 Proteins) receptor assembly to different extents, an effect that could be potentially rescued by facilitating protein folding and assembly.

  10. These results present no evidence for an association of rs211037 with JME. Further studies are required to investigate the involvement of the GABRG2 gene in the genetic susceptibility to this epileptic syndrome.

Mouse (Murine) gamma-aminobutyric Acid (GABA) A Receptor, gamma 2 (GABRG2) interaction partners

  1. This investigation demonstrates striking interfacial GABAA (show GABRg1 Proteins) receptor subunit selectivity in the native milieu, suggesting that asymmetric occupancy of heteropentameric ion channels by alkylphenol-based anesthetics is sufficient to induce modulation of activity.

  2. Study shows that the down-regulation of the gamma2 subunit of postsynaptic GABAARs in NG2 (show Vcan Proteins) cells that accompanies the postnatal switch from synaptic to extrasynaptic GABAergic transmission between interneurons and these cells in the barrel cortex

  3. Dendritic spine abnormalities of Gabrg2+/- mice suggest association of functional defects in glutamatergic transmission with the established anxious-depressive phenotype of these mice

  4. KIF21B participates in the delivery of GABAAR transport vesicles into dendrites.

  5. The study demonstrates the molecular and functional diversity of the GABAAR system within the mouse colon providing a framework for developing GABAAR-based therapeutics in GI disorders.

  6. these findings suggest that gephyrin (show GPHN Proteins) may be a key factor in BDNF (show BDNF Proteins)-dependent GABAAR regulation in the amygdala.

  7. This study showed that oscillatory activity in thalamic circuits is under the control of inhibition that involves gamma2 subunit-independent GABA-ARs (show SLURP1 Proteins)

  8. Tyrosine phosphorylation of GABAA (show GABRg1 Proteins) receptor gamma2-subunit regulates tonic and phasic inhibition in the Lateral Geniculate Body in mice.

  9. Expression of the gamma2-subunit distinguishes synaptic and extrasynaptic GABA(A) receptors in NG2 (show Vcan Proteins) cells of the hippocampus

  10. The results suggested that juvenile and adult stressor experiences elicit variations of GABAA (show GABRg1 Proteins) receptor subunit expression that are region-specific as well as sexually-dimorphic. Stressful events during the juvenile.

GABRG2 Protein Profile

Protein Summary

This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammlian brain, where it acts at GABA-A receptors, which are ligand-gated chloride channels. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene have been associated with epilepsy and febrile seizures. Multiple transcript variants encoding different isoforms have been identified for this gene.

Gene names and symbols associated with GABRG2

  • gamma-aminobutyric acid (GABA) A receptor, gamma 2 (GABRG2)
  • gamma-aminobutyric acid (GABA) A receptor, gamma 2 (gabrg2)
  • gamma-aminobutyric acid (GABA) A receptor, gamma 2 (Gabrg2)
  • gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2 (Gabrg2)
  • CAE2 protein
  • ECA2 protein
  • GABAA-R protein
  • Gabrg-2 protein
  • gabrg1 protein
  • gamma2 protein
  • GEFSP3 protein
  • si:ch211-145n14.1 protein

Protein level used designations for GABRG2

gamma-aminobutyric acid A receptor, gamma 1 , GABA(A) receptor subunit gamma-2 , gamma-aminobutyric acid receptor subunit gamma-2 , gamma-aminobutyric acid A receptor gamma 2 , gamma-aminobutyric acid (GABA) A receptor, gamma 2 , gamma-aminobutyric acid receptor subunit gamma-2-like , gamma-aminobutyric acid A receptor, gamma 2 , gamma-aminobutyric acid (GABA-A) receptor, subunit gamma 2 , gamma-aminobutyric acid A receptor, gamma 2 , GABA-A receptor gamma-2 subunit , GABA(A) receptor, gamma 2

GENE ID SPECIES
100059571 Equus caballus
779514 Xenopus (Silurana) tropicalis
100174267 Pongo abelii
100286791 Felis catus
100405062 Callithrix jacchus
29709 Rattus norvegicus
553402 Danio rerio
396289 Gallus gallus
2566 Homo sapiens
489141 Canis lupus familiaris
282240 Bos taurus
100516405 Sus scrofa
14406 Mus musculus
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