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MPPED2 likely encodes a metallophosphoesterase. Additionally we are shipping MPPED2 Antibodies (45) and many more products for this protein.
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The overexpression of Mpped2 improves survival rate, substantially impairs tumor growth and induces neuronal differentiation.
The structures of MPPED2 and two mutants show that the poor activity of MPPED2 is not only a consequence of the substitution of an active-site histidine residue by glycine but also due to binding of AMP (show APRT Proteins) or GMP (show NT5C2 Proteins) to the active site.
This gene likely encodes a metallophosphoesterase. The encoded protein may play a role a brain development. Alternatively spliced transcript variants have been described.
, fetal brain protein 239
, metallophosphoesterase domain-containing protein 2
, fetal brain protein 239 homolog
, putative C11orf8 homolog
, metallophosphoesterase domain containing 2