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anti-omega-3 Fatty Acid Receptor 1 (O3FAR1) Antibodies

O3FAR1 encodes a G protein-coupled receptor (GPR) which belongs to the rhodopsin family of GPRs. Additionally we are shipping omega-3 Fatty Acid Receptor 1 Kits (22) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
O3FAR1 338557 Q5NUL3
O3FAR1 107221 Q7TMA4
O3FAR1 294075 Q2AC31
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Top anti-omega-3 Fatty Acid Receptor 1 Antibodies at antibodies-online.com

Showing 10 out of 107 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IF, ELISA, WB Western blot analysis of extracts from LOVO cells, using GPR120 Antibody. The lane on the right is treated with the synthesized peptide. Immunofluorescence analysis of LOVO cells, using GPR120 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated IHC (p) Immunohistochemistry-Paraffin: FFAR4/GPR120 Antibody [NLS2006] - Human colon formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Immunohistochemistry-Paraffin: FFAR4/GPR120 Antibody [NLS2006] - Analysis of anti-O3FAR1 / GPR120 antibody with small intestine, enterocytes at 4 ug/ ml. 0.05 mL Log in to see 5 to 7 Days
$447.56
Details
Human Rabbit Un-conjugated IHC (p) Immunohistochemistry-Paraffin: FFAR4/GPR120 Antibody [NLS2004] - Analysis of anti-O3FAR1 / GPR120 antibody with human colon, surface epithelium. Immunohistochemistry-Paraffin: FFAR4/GPR120 Antibody [NLS2004] - Analysis of anti-O3FAR1 / GPR120 antibody with human colon, crypts. 0.05 mL Log in to see 5 to 7 Days
$447.56
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), WB Immunohistochemistry-Paraffin: FFAR4/GPR120 Antibody [NBP1-00858] - IHC analysis of formalin fixed paraffin embedded tissue section of mouse intestine using FFAR4/GPR120 antibody at 1:200 dilution. The intestinal epithelial cells showed an expected cytoplasmic staining (immunogen of NBP1-00858 corresponds to the cytoplasmic domain of GPR120 protein ), while some cells especially the goblet cells population depicted nuclear positivity also. The observed nuclear signal may be justified on the fact that - some GPCRs are known for nuclear translocation upon binding to extracellular or endogenous/non-secreted ligands, wherein they impact the trancriptional regulation via GPCR-heterotrimeric G-protein-effector complexes. Immunocytochemistry/Immunofluorescence: FFAR4/GPR120 Antibody [NBP1-00858] - GPR120 antibody was tested at 1:50 in HeLa cells with Dylight 488 (green). Nuclei and alpha-tubulin were counterstained with DAPI (blue) and Dylight 550 (red). Image objective 40x. 0.1 mg Log in to see 5 to 7 Days
$473.81
Details
Human Rabbit Un-conjugated ELISA, IF, WB Western Blot (WB) analysis of specific cells using GPR120 Polyclonal Antibody. 100 μL Log in to see 14 Days
$175.80
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p) Immunohistochemistry-Paraffin: FFAR4/GPR120 Antibody [NLS2003] - Analysis of anti-O3FAR1 / GPR120 antibody with human colon. 0.05 mL Log in to see 5 to 7 Days
$447.56
Details
Human Rabbit Un-conjugated WB GPR120 Antibody (Center)  western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the GPR120 antibody detected the GPR120 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), WB Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μL Log in to see 8 to 10 Days
$451.00
Details
Human Goat Un-conjugated ELISA, IHC (p), WB   0.1 mg Log in to see 5 to 7 Days
$317.63
Details

O3FAR1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-omega-3 Fatty Acid Receptor 1 Antibodies

  1. Human Polyclonal O3FAR1 Primary Antibody for ICC, IF - ABIN314627 : Liu, Chen, Sokolowska, Eberlein, Alsaaty, Martinez-Anton, Logun, Qi, Shelhamer: The fish oil ingredient, docosahexaenoic acid, activates cytosolic phospholipase A₂ via GPR120 receptor to produce prostaglandin E₂ and plays an anti-inflammatory role in macrophages. in Immunology 2014 (PubMed)
    Show all 7 references for ABIN314627

  2. Human Polyclonal O3FAR1 Primary Antibody for ELISA, IHC (p) - ABIN451730 : Gotoh, Hong, Iga, Hishikawa, Suzuki, Song, Choi, Adachi, Hirasawa, Tsujimoto, Sasaki, Roh: The regulation of adipogenesis through GPR120. in Biochemical and biophysical research communications 2007 (PubMed)

  3. Human Polyclonal O3FAR1 Primary Antibody for IF, ELISA - ABIN1535626 : Deloukas, Earthrowl, Grafham, Rubenfield, French, Steward, Sims, Jones, Searle, Scott, Howe, Hunt, Andrews, Gilbert, Swarbreck, Ashurst, Taylor, Battles, Bird, Ainscough, Almeida, Ashwell, Ambrose et al.: The DNA sequence and comparative analysis of human chromosome 10. ... in Nature 2004 (PubMed)

  4. Human Polyclonal O3FAR1 Primary Antibody for IHC (p) - ABIN270758 : Milton, Khaire, Ingram, ODonnell, La Thangue: 14-3-3 proteins integrate E2F activity with the DNA damage response. in The EMBO journal 2006 (PubMed)

  5. Human Polyclonal O3FAR1 Primary Antibody for IHC (p) - ABIN4311410 : Li, Kokrashvili, Mosinger, Margolskee: Gustducin couples fatty acid receptors to GLP-1 release in colon. in American journal of physiology. Endocrinology and metabolism 2013 (PubMed)

More Antibodies against omega-3 Fatty Acid Receptor 1 Interaction Partners

Human omega-3 Fatty Acid Receptor 1 (O3FAR1) interaction partners

  1. It promotes the secretion of glucagon-like peptide-1 (GLP-1 (show GCG Antibodies)) in the intestine, and also acts as a lipid sensor in adipose tissue to sense dietary fat and control energy balance.(review)

  2. demonstrated a GPR120-mediated novel anti-inflammatory pathway in specific intestinal epithelial cell types that could be of therapeutic relevance to intestinal inflammatory disorders

  3. GPR120 negatively and GPR40 (show FFAR1 Antibodies) positively regulate cellular functions during tumor progression in lung cancer cells.

  4. the low-frequency p.R270H variant which inhibits GPR120 activity might influence fasting glucose levels in a normal physiological range.

  5. GPR120 functions as a receptor for omega-3 fatty acid, involving in regulating the secretion of gastrointestinal peptide (show SPINK4 Antibodies) hormone, adipogenesis, adipogenic differentiation and anti-inflammatory process. [review]

  6. Characterizing pharmacological ligands to study the long-chain fatty acid receptors GPR40 (show FFAR1 Antibodies)/FFA1 and GPR120/FFA4

  7. Findings demonstrate the novel functional properties of GPR120 on human eosinophils and indicate the previously unrecognized link between nutrient metabolism and the immune system.

  8. These results suggest that distinct effects of GPR120 and GPR40 (show FFAR1 Antibodies) are involved in the acquisition of malignant property in pancreatic cancer cells.

  9. TNFa (show TNF Antibodies) decreases GLP-2 (show GCG Antibodies) expression by up-regulating GPR120 in Crohn disease

  10. Morbidly obese subjects had lower GPR120 mRNA and protein levels in visceral adipose tissue and a lower mRNA expression after a high-fat meal in peripheral blood mononuclear cells.

Mouse (Murine) omega-3 Fatty Acid Receptor 1 (O3FAR1) interaction partners

  1. demonstrated a GPR120-mediated novel anti-inflammatory pathway in specific intestinal epithelial cell types that could be of therapeutic relevance to intestinal inflammatory disorders

  2. Data suggest phosphorylation of Ffar4 occurs at 3 serine and 2 threonine residues clustered in 2 separable regions of C-terminal tail; recruitment of arrestin 3 (show ARRB2 Antibodies), receptor internalization, and activation of Akt (show AKT1 Antibodies) are regulated by Ffar4 phosphorylation.

  3. GPR120-mediated cellular signalling determines the bi-potential differentiation of BMMSCs in a dose-dependent manner.

  4. GPR 40 (show FFAR1 Antibodies)/120 double-knockout mice are impaired in post-oral fat sensing.

  5. co-transfection of GPR120 enhanced eicosapentaenoic acid-induced PPARgamma (show PPARG Antibodies) binding to PPAR (show PPARA Antibodies)-response element in VEGF-A (show VEGFA Antibodies) promoter region.

  6. results indicated that the beneficial metabolic role of DHA was attributed to its ability to regulate glucose via the GPR120-mediated AMPK (show PRKAA1 Antibodies) pathway in the skeletal muscles

  7. The GPR120 in mouse pituitary gonadotropes is upregulated by fasting and that it may play a role in controlling gonadotropin secretion.

  8. Results suggest that GPR120 is not indispensable for the improved metabolic profile associated with intake of a diet enriched in n-3 polyunsaturated fatty acids.

  9. GPR120 is expressed abundantly in K cells of the upper small intestine and plays a critical role in lipid-induced GIP (show GIP Antibodies) secretion.

  10. The results imply that GPR120 is selectively present within the delta cells of murine islets and that it regulates somatostatin (show SST Antibodies) secretion.

Pig (Porcine) omega-3 Fatty Acid Receptor 1 (O3FAR1) interaction partners

  1. GPR120 is highly expressed in porcine mature adipose tissue and is positively associated with adipose tissue development. 5 CpG islands across GPR120 gene exhibit different methylation states. DNA methylation (show HELLS Antibodies) of GPR120 5'-untranslated and first exon regions can negatively regulate its expression levels.

  2. C/EBP-beta (show CEBPB Antibodies) plays a vital role in regulating GPR120 transcription.

omega-3 Fatty Acid Receptor 1 (O3FAR1) Antigen Profile

Protein Summary

This gene encodes a G protein-coupled receptor (GPR) which belongs to the rhodopsin family of GPRs. The encoded protein functions as a receptor for free fatty acids, including omega-3, and participates in suppressing anti-inflammatory responses and insulin sensitizing. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with O3FAR1

  • free fatty acid receptor 4 (FFAR4) antibody
  • free fatty acid receptor 4 (Ffar4) antibody
  • free fatty acid receptor 4-like (LOC533266) antibody
  • G protein-coupled receptor 120 (LOC100343591) antibody
  • omega-3 fatty acid receptor 1 (O3FAR1) antibody
  • AI552415 antibody
  • BMIQ10 antibody
  • Gpr120 antibody
  • Gpr129 antibody
  • GT01 antibody
  • KPG_013 antibody
  • O3far1 antibody
  • Pgr4 antibody

Protein level used designations for O3FAR1

G-protein coupled receptor 120 , G-protein coupled receptor 129 , G-protein coupled receptor GT01 , G-protein coupled receptor PGR4 , omega-3 fatty acid receptor 1 , G protein-coupled receptor 120 , G-protein-coupled receptor GT01

GENE ID SPECIES
338557 Homo sapiens
107221 Mus musculus
294075 Rattus norvegicus
533266 Bos taurus
100343591 Oryctolagus cuniculus
477774 Canis lupus familiaris
100135678 Sus scrofa
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