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O3FAR1 encodes a G protein-coupled receptor (GPR) which belongs to the rhodopsin family of GPRs. Additionally we are shipping omega-3 Fatty Acid Receptor 1 Kits (22) and and many more products for this protein.
Showing 10 out of 107 products:
Human Polyclonal O3FAR1 Primary Antibody for ICC, IF - ABIN314627
Liu, Chen, Sokolowska, Eberlein, Alsaaty, Martinez-Anton, Logun, Qi, Shelhamer: The fish oil ingredient, docosahexaenoic acid, activates cytosolic phospholipase A₂ via GPR120 receptor to produce prostaglandin E₂ and plays an anti-inflammatory role in macrophages. in Immunology 2014
Show all 7 references for ABIN314627
Human Polyclonal O3FAR1 Primary Antibody for ELISA, IHC (p) - ABIN451730
Gotoh, Hong, Iga, Hishikawa, Suzuki, Song, Choi, Adachi, Hirasawa, Tsujimoto, Sasaki, Roh: The regulation of adipogenesis through GPR120. in Biochemical and biophysical research communications 2007
Human Polyclonal O3FAR1 Primary Antibody for IF, ELISA - ABIN1535626
Deloukas, Earthrowl, Grafham, Rubenfield, French, Steward, Sims, Jones, Searle, Scott, Howe, Hunt, Andrews, Gilbert, Swarbreck, Ashurst, Taylor, Battles, Bird, Ainscough, Almeida, Ashwell, Ambrose et al.: The DNA sequence and comparative analysis of human chromosome 10. ... in Nature 2004
Human Polyclonal O3FAR1 Primary Antibody for IHC (p) - ABIN270758
Milton, Khaire, Ingram, ODonnell, La Thangue: 14-3-3 proteins integrate E2F activity with the DNA damage response. in The EMBO journal 2006
Human Polyclonal O3FAR1 Primary Antibody for IHC (p) - ABIN4311410
Li, Kokrashvili, Mosinger, Margolskee: Gustducin couples fatty acid receptors to GLP-1 release in colon. in American journal of physiology. Endocrinology and metabolism 2013
It promotes the secretion of glucagon-like peptide-1 (GLP-1 (show GCG Antibodies)) in the intestine, and also acts as a lipid sensor in adipose tissue to sense dietary fat and control energy balance.(review)
demonstrated a GPR120-mediated novel anti-inflammatory pathway in specific intestinal epithelial cell types that could be of therapeutic relevance to intestinal inflammatory disorders
GPR120 negatively and GPR40 (show FFAR1 Antibodies) positively regulate cellular functions during tumor progression in lung cancer cells.
the low-frequency p.R270H variant which inhibits GPR120 activity might influence fasting glucose levels in a normal physiological range.
GPR120 functions as a receptor for omega-3 fatty acid, involving in regulating the secretion of gastrointestinal peptide (show SPINK4 Antibodies) hormone, adipogenesis, adipogenic differentiation and anti-inflammatory process. [review]
Characterizing pharmacological ligands to study the long-chain fatty acid receptors GPR40 (show FFAR1 Antibodies)/FFA1 and GPR120/FFA4
Findings demonstrate the novel functional properties of GPR120 on human eosinophils and indicate the previously unrecognized link between nutrient metabolism and the immune system.
These results suggest that distinct effects of GPR120 and GPR40 (show FFAR1 Antibodies) are involved in the acquisition of malignant property in pancreatic cancer cells.
TNFa (show TNF Antibodies) decreases GLP-2 (show GCG Antibodies) expression by up-regulating GPR120 in Crohn disease
Morbidly obese subjects had lower GPR120 mRNA and protein levels in visceral adipose tissue and a lower mRNA expression after a high-fat meal in peripheral blood mononuclear cells.
Data suggest phosphorylation of Ffar4 occurs at 3 serine and 2 threonine residues clustered in 2 separable regions of C-terminal tail; recruitment of arrestin 3 (show ARRB2 Antibodies), receptor internalization, and activation of Akt (show AKT1 Antibodies) are regulated by Ffar4 phosphorylation.
GPR120-mediated cellular signalling determines the bi-potential differentiation of BMMSCs in a dose-dependent manner.
GPR 40 (show FFAR1 Antibodies)/120 double-knockout mice are impaired in post-oral fat sensing.
co-transfection of GPR120 enhanced eicosapentaenoic acid-induced PPARgamma (show PPARG Antibodies) binding to PPAR (show PPARA Antibodies)-response element in VEGF-A (show VEGFA Antibodies) promoter region.
results indicated that the beneficial metabolic role of DHA was attributed to its ability to regulate glucose via the GPR120-mediated AMPK (show PRKAA1 Antibodies) pathway in the skeletal muscles
The GPR120 in mouse pituitary gonadotropes is upregulated by fasting and that it may play a role in controlling gonadotropin secretion.
Results suggest that GPR120 is not indispensable for the improved metabolic profile associated with intake of a diet enriched in n-3 polyunsaturated fatty acids.
GPR120 is expressed abundantly in K cells of the upper small intestine and plays a critical role in lipid-induced GIP (show GIP Antibodies) secretion.
The results imply that GPR120 is selectively present within the delta cells of murine islets and that it regulates somatostatin (show SST Antibodies) secretion.
GPR120 is highly expressed in porcine mature adipose tissue and is positively associated with adipose tissue development. 5 CpG islands across GPR120 gene exhibit different methylation states. DNA methylation (show HELLS Antibodies) of GPR120 5'-untranslated and first exon regions can negatively regulate its expression levels.
C/EBP-beta (show CEBPB Antibodies) plays a vital role in regulating GPR120 transcription.
This gene encodes a G protein-coupled receptor (GPR) which belongs to the rhodopsin family of GPRs. The encoded protein functions as a receptor for free fatty acids, including omega-3, and participates in suppressing anti-inflammatory responses and insulin sensitizing. Multiple transcript variants encoding different isoforms have been found for this gene.
G-protein coupled receptor 120
, G-protein coupled receptor 129
, G-protein coupled receptor GT01
, G-protein coupled receptor PGR4
, omega-3 fatty acid receptor 1
, G protein-coupled receptor 120
, G-protein-coupled receptor GT01