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phosphodiesterase 11A (PDE11A) ELISA Kits

The 3',5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. Additionally we are shipping PDE11A Antibodies (67) and PDE11A Proteins (5) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human PDE11A PDE11A 50940 Q9HCR9
Anti-Rat PDE11A PDE11A 140928 Q8VID6
Anti-Mouse PDE11A PDE11A 241489 P0C1Q2
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More ELISA Kits for PDE11A Interaction Partners

Human phosphodiesterase 11A (PDE11A) interaction partners

  1. One percent of the Swedish population carries a PDE11A loss-of-function mutation which is associated with elevated BP, abdominal obesity, and risk of ischemic stroke.

  2. Testicular germ cell tumors had 55 PDE11A variants: 20 missense (10 new, 9 in transcript variant 4, 1 in transcript variant 3), 4 splice-site, 2 nonsense, 7 synonymous, and 22 intronic. p.F258Y, p.G291R, p.V820M, p.R545X, and p.K568R were only in cases.

  3. PDE11A genetic variants may increase predisposition to ACTH (show POMC ELISA Kits)-independent macronodular adrenal hyperplasia.

  4. Our data suggest that, like in the adrenal cortex and the testicular germ cells, PDE11A-inactivating genetic alterations may play a role in susceptibility to prostate cancer

  5. We demonstrate, in a large cohort of Carney Complex patients, a high frequency of PDE11A variants, suggesting that PDE11A is a genetic modifying factor for the development of testicular and adrenal tumors in patients with germline PRKAR1A (show PRKAR1A ELISA Kits) mutation.

  6. PDE11A SNP assocaited with allergic asthma.

  7. PDE11A genetic defects may be associated with adrenal pathology in a wider than previously suspected and is associated with adrenal hyperplasia and adenomas.

  8. Variants in PDE11A are not associated with citalopram response in patient with depression.

  9. PDE11A is expressed widely in adrenal cortex. Its expression appears to be increased in PPNAD but varies widely among other adrenocortical tumors.

  10. PDE11A sequence defects predispose to a variety of lesions (beyond micronodular adrenocortical hyperplasia).

Mouse (Murine) phosphodiesterase 11A (PDE11A) interaction partners

  1. PDE11A knockout mice show subtle psychiatric-disease-related deficits, including hyperactivity in an open field, increased sensitivity to the glutamate N-methyl-D-aspartate receptor (show GRIN3A ELISA Kits) antagonist MK-801, as well as deficits in social behaviors

PDE11A Antigen Profile

Antigen Summary

The 3',5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3',5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a member of the PDE protein superfamily. Mutations in this gene are a cause of Cushing disease and adrenocortical hyperplasia. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with PDE11A

  • phosphodiesterase 11A (PDE11A) antibody
  • phosphodiesterase 11a (pde11a) antibody
  • phosphodiesterase 11a, like (pde11al) antibody
  • phosphodiesterase 11A (pde11a) antibody
  • phosphodiesterase 11a (Pde11a) antibody
  • phosphodiesterase 11A (Pde11a) antibody
  • 6330414F14Rik antibody
  • A630086N24Rik antibody
  • Gm350 antibody
  • Pde11a antibody
  • PDE11A1 antibody
  • PPNAD2 antibody
  • si:ch211-222f23.5 antibody
  • wu:ft39g12 antibody

Protein level used designations for PDE11A

phosphodiesterase 11A , dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A , dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A-like , phosphodiesterase 11a , cAMP and cGMP cyclic nucleotide phosphodiesterase 11A , cAMP and cGMP phosphodiesterase 11A

GENE ID SPECIES
424133 Gallus gallus
524446 Bos taurus
561338 Danio rerio
569112 Danio rerio
702458 Macaca mulatta
740616 Pan troglodytes
100026785 Monodelphis domestica
100053692 Equus caballus
100084944 Ornithorhynchus anatinus
100225567 Taeniopygia guttata
100341520 Oryctolagus cuniculus
100379882 Xenopus (Silurana) tropicalis
100397766 Callithrix jacchus
100470038 Ailuropoda melanoleuca
100302674 Cavia porcellus
50940 Homo sapiens
140928 Rattus norvegicus
241489 Mus musculus
488422 Canis lupus familiaris
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