You are viewing an incomplete version of our website. Please click to reload the website as full version.

phosphodiesterase 4A, CAMP-Specific Proteins (PDE4A)

The protein encoded by PDE4A belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. Additionally we are shipping phosphodiesterase 4A, CAMP-Specific Antibodies (75) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PDE4A 18577 O89084
PDE4A 5141 P27815
PDE4A 25638 P54748
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top phosphodiesterase 4A, CAMP-Specific Proteins at antibodies-online.com

Showing 8 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Baculovirus infected Insect Cells Human GST tag   5 μg Log in to see 10 to 12 Days
$365.64
Details
HOST_Escherichia coli (E. coli) Elk Un-conjugated   5 applications Log in to see 1 to 2 Days
$344.14
Details
HOST_Escherichia coli (E. coli) Chicken Un-conjugated   5 applications Log in to see 1 to 2 Days
$344.14
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   5 applications Log in to see 1 to 2 Days
$344.14
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

PDE4A Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , , ,
,
Rat (Rattus)

More Proteins for phosphodiesterase 4A, CAMP-Specific (PDE4A) Interaction Partners

Mouse (Murine) phosphodiesterase 4A, CAMP-Specific (PDE4A) interaction partners

  1. PDE4 inhibition reduces neointima formation and inhibits VCAM-1 (show VCAM1 Proteins) expression and histone methylation in an Epac (show RAPGEF3 Proteins)-dependent manner.

  2. results suggest that PDE4A may be important in the regulation of emotional memory and anxiety-like behavior, but not emesis

  3. This study showed that long PDE4 isoforms provide a novel node for cross-talk between the cAMP and p38 MAPK (show MAPK14 Proteins) signalling systems at the level of MK2 (show KCNA2 Proteins).

  4. Increased cAMP may remodel cAMP-mediated signalling events by not only increasing the expression of specific PDE4 cAMP phosphodiesterases but also by down-regulating specific isoforms, such as is shown here for PDE4A10 in cardiac myocytes.

  5. a new mechanism in which phosphodiesterase PDE4A4/5 interacts with p75(NTR (show NGFR Proteins)) to enhance cAMP degradation

Human phosphodiesterase 4A, CAMP-Specific (PDE4A) interaction partners

  1. curcumin exerts its in vitro anti-angiogenic and in vivo anti-tumour properties through combined PDE2 (show PDE2A Proteins) and PDE4 inhibition

  2. After 48 h yessotoxin treatment PDE4A-dependent autophagy, as non-apoptotic programmed cell death, is activated.

  3. AKAP 149 (show AKAP1 Proteins)-PKA-PDE4A complex localization is related with YTX effect in K-562 cell line

  4. Hydroxycarbamide decreases sickle reticulocyte adhesion to resting endothelium by inhibiting endothelial lutheran/basal cell adhesion molecule (Lu/BCAM (show BCAM Proteins)) through phosphodiesterase 4A activation.

  5. long-acting beta -agonist and PDE4 inhibitor have a synergistic effect in regulating fibroblast tissue repair functions and PGE2 can modulate the effect of beta -agonist and PDE4 inhibitor at least in part through the mechanism of regulating PDE4 expression

  6. PDE4A and PDE4C (show PDE4C Proteins) work in redundant fashion to mediate the loss of inhibitory PGE2 signaling in lung fibroblasts.

  7. In phosphoinositide 3-kinasegamma-deficient cardiomyocytes, coincident signaling of the major cardiac PDE3 and PDE4 isoforms orchestrates a feedback loop that prevents calcium-dependent ventricular arrhythmia.

  8. Data demonstrate that upregulation of Nox4 (show NOX4 Proteins) leads to an upregulation of PDE4A, B, and D and increased hydrolysis of cAMP which in turn augments cell replication and angiogenesis.

  9. These results indicate that PDE4A and PLAT (show PLAT Proteins) may be susceptibility genes for schizophrenia in the Japanese population.

  10. we have identified a so-far-unknown interaction between LIS1 (show PAFAH1B1 Proteins) and PDE4 isoforms, whereby PDE4 can modulate LIS1 (show PAFAH1B1 Proteins)-dynein complexes and dynein-dependent processes within cells by sequestering LIS1 (show PAFAH1B1 Proteins).

phosphodiesterase 4A, CAMP-Specific (PDE4A) Protein Profile

Protein Summary

The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Gene names and symbols associated with PDE4A

  • phosphodiesterase 4A, cAMP-specific (pde4a)
  • phosphodiesterase 4A, cAMP-specific (phosphodiesterase E2 dunce homolog, Drosophila) (PDE4A)
  • phosphodiesterase 4A, cAMP-specific (PDE4A)
  • phosphodiesterase 4A, cAMP specific (Pde4a)
  • phosphodiesterase 4A, cAMP-specific (Pde4a)
  • D9Ertd60e protein
  • DPDE2 protein
  • PDE4 protein
  • Pde4a protein
  • PDE46 protein
  • PHOSA protein

Protein level used designations for PDE4A

phosphodiesterase 4A, cAMP-specific , phosphodiesterase 4A-like , phosphodiesterase 4A, cAMP-specific (phosphodiesterase E2 dunce homolog, Drosophila) , cyclic AMP-specific phosphodiesterase FCPDE4A1A , cyclic AMP-specific phosphodiesterase OCPDE4A1A , phosphodiesterase 4A, cAMP specific , cyclic AMP-specific phosphodiesterase CPPDE4A1A , cAMP-specific 3',5'-cyclic phosphodiesterase 4A , cAMP-specific phosphodiesterase PDE4A , cyclic AMP specific phosphodiesterase PDE4A5A , dunce , phosphodiesterase 4A, cAMP-specific (dunce , phosphodiesterase E2 dunce homolog, Drosophila , phosphodiesterase isozyme 4 , DPDE2 , cyclic AMP-specific phosphodiesterase SSPDE4A1A

GENE ID SPECIES
495146 Xenopus laevis
572061 Danio rerio
712850 Macaca mulatta
747380 Pan troglodytes
751107 Felis catus
100009247 Oryctolagus cuniculus
100135594 Cavia porcellus
100567896 Anolis carolinensis
100596792 Nomascus leucogenys
18577 Mus musculus
5141 Homo sapiens
769860 Gallus gallus
25638 Rattus norvegicus
100683695 Canis lupus familiaris
396825 Sus scrofa
512222 Bos taurus
Selected quality suppliers for phosphodiesterase 4A, CAMP-Specific Proteins (PDE4A)
Did you look for something else?