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phosphodiesterase 4B, CAMP-Specific (PDE4B) ELISA Kits

PDE4B is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. Additionally we are shipping phosphodiesterase 4B, CAMP-Specific Antibodies (90) and phosphodiesterase 4B, CAMP-Specific Proteins (7) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Mouse PDE4B PDE4B 18578  
PDE4B 24626 P14646
PDE4B 5142 Q07343
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Top phosphodiesterase 4B, CAMP-Specific ELISA Kits at

Showing 2 out of 6 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Rat 0.065 ng/mL 0.15-10 ng/mL 96 Tests Log in to see 9 to 11 Days
Human 0.156-10 ng/mL   96 Tests Log in to see 11 to 13 Days

More ELISA Kits for phosphodiesterase 4B, CAMP-Specific Interaction Partners

Mouse (Murine) phosphodiesterase 4B, CAMP-Specific (PDE4B) interaction partners

  1. PDE4B phosphorylated by AMPK (show PRKAA1 ELISA Kits) at Ser304 is important for activation.

  2. Lymphomas developing in a Pde4b-null background display significantly lower microvessel density in association with lower VEGF (show VEGFA ELISA Kits) levels and PI3K/AKT (show AKT1 ELISA Kits) activity.

  3. Genetic variations in DISC1 influence formation of biochemical complex with PDE4 and GSK-3 and strengthen the possibility of synergistic interactions between these proteins.

  4. PDE4B-deficient mice display impaired reversal learning in the Morris water maze compared to wild-type littermates.

  5. Results identify PDE4B in the CaV1.2 (show CACNA1C ELISA Kits) complex as a critical regulator of ICa (show ICA ELISA Kits) during beta-AR stimulation and suggest that distinct PDE4 (show PDE4A ELISA Kits) subtypes are important for normal regulation of calcium-induced calcium release in cardiomyocytes.

  6. Findings demonstrate that PDE4D (show PDE4D ELISA Kits) and PDE4B have specialized functions in mouse embryonic fibroblasts with PDE4B controlling cAMP in a discrete subdomain near the plasma membrane.

  7. induction is esssential for LPS (show TLR4 ELISA Kits)-activated tnf-alpha (show TNF ELISA Kits) responses

  8. PDE4B mediates the antipsychotic effects of rolipram in conditioned avoidance responding; the PDE4B-regulated cyclic adenosine monophosphate signaling pathway may play a role in the pathophysiology and pharmacotherapy of psychosis

  9. the PDE4B subfamily is involved in signaling pathways that contribute to anxiogenic-like effects on behavior.

  10. Altered DISC1 (show DISC1 ELISA Kits)-PDE4B interaction may thus underlie the symptoms of some cases of schizophrenia and depression.(Review)

Human phosphodiesterase 4B, CAMP-Specific (PDE4B) interaction partners

  1. This meta-analysis suggests that PDE4B SNPs are genetically associated with susceptibility to schizophrenia.

  2. Our results suggest that PDE4B does not play an important role during the chemotactic response of human neutrophils

  3. Our results support previously reported association of PDE4B variations with schizophrenia in other populations.

  4. analysis of the mechanism underlying synergistic up-regulation of PDE4B2 via a cross-talk between PKA-Cbeta and p65 (show GORASP1 ELISA Kits)

  5. ototopical post-inoculation administration of a PDE4 (show PDE4A ELISA Kits) inhibitor suppresses inflammation in this animal model, thus demonstrating the therapeutic potential of targeting PDE4 (show PDE4A ELISA Kits)

  6. PDE4B was found to be highly expressed in CD4 (show CD4 ELISA Kits)+ lymphoid cancer cells, which suggests that it may represent a physiological role unique to the CD8 (show CD8A ELISA Kits)+ and lymphoid cancer cells and thus might represent a target for treatment of certain lymphoid diseases

  7. Short Disrupted-in-Schizophrenia (DISC)1 splice variants show reduced or no binding to nudE nuclear distribution E homolog (NDEL)1 and PDE4B proteins but fully interact with fasciculation/elongation zeta (FEZ)1 and glycogen synthase kinase 3 GSK3beta.

  8. PDE4B mediates ERK (show EPHB2 ELISA Kits)-dependent up-regulation of mucin (show SLC13A2 ELISA Kits) MUC5AC by S. pneumoniae by inhibiting cAMP-PKA-dependent MKP-1 (show DUSP1 ELISA Kits) pathway.

  9. a study of Northwestern Han Chinese found that rs472952 is significantly associated with schizophrenia (SCZ) and rs7537440 is associated with SCZ in females; results provide further evidence that PDE4B may play important roles in the etiology of SCZ

  10. PDE4B was downregulated and the protein kinase A pathway was activated in castration-resistant LNCaP prostate cancer cells. PDE4B expression was reduced in advanced prostate cancer and PDE4B knockdown promoted castration-resistant growth of LNCaP cells.

Pig (Porcine) phosphodiesterase 4B, CAMP-Specific (PDE4B) interaction partners

  1. QTL-CI for IMF (show MDFI ELISA Kits) was reconfirmed with high significance, and its position was narrowed down to an interval of 4 cM (the region defined by markers PDE4B and SW1881)

phosphodiesterase 4B, CAMP-Specific (PDE4B) Antigen Profile

Antigen Summary

This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. Cyclic nucleotides are important second messengers that regulate and mediate a number of cellular responses to extracellular signals, such as hormones, light, and neurotransmitters. The cyclic nucleotide phosphodiesterases (PDEs) regulate the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. This gene encodes a protein that specifically hydrolyzes cAMP. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Gene names and symbols associated with PDE4B

  • phosphodiesterase 4B, cAMP-specific (pde4b) antibody
  • phosphodiesterase 4B, cAMP-specific (PDE4B) antibody
  • phosphodiesterase 4B, cAMP specific (Pde4b) antibody
  • DPDE4 antibody
  • dunce antibody
  • PDE4/IVb antibody
  • Pde4B1 antibody
  • Pde4B2 antibody
  • Pde4B3 antibody
  • Pde4B4 antibody
  • PDE4B5 antibody
  • PDEIVB antibody
  • R74983 antibody

Protein level used designations for PDE4B

phosphodiesterase 4B, cAMP-specific (phosphodiesterase E4 dunce homolog) , phosphodiesterase 4B, cAMP-specific , phosphodiesterase 4B , 3',5'-cyclic AMP phosphodiesterase , DPDE4 , Phosphodiesterase 4B cAMP-specific (dunce , Phosphodiesterase 4B, cAMP-specific (dunce , cAMP-specific 3',5'-cyclic phosphodiesterase 4B , PDE32 , cAMP-specific phosphodiesterase-4 B isoform , dunce-like phosphodiesterase E4 , phosphodiesterase 4B, cAMP-specific (phosphodiesterase E4 dunce homolog, Drosophila) , phosphodiesterase 4B, cAMP specific

780324 Xenopus (Silurana) tropicalis
100604983 Nomascus leucogenys
18578 Mus musculus
24626 Rattus norvegicus
5142 Homo sapiens
424700 Gallus gallus
444562 Xenopus laevis
100037941 Sus scrofa
100124505 Bos taurus
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