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The protein encoded by PDE4C belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. Additionally we are shipping phosphodiesterase 4C, CAMP-Specific Proteins (6) and many more products for this protein.
Showing 10 out of 53 products:
Human Polyclonal PDE4C Primary Antibody for IP, WB - ABIN493277
Hoffmann, Wilkinson, McCallum, Engels, Houslay: cAMP-specific phosphodiesterase HSPDE4D3 mutants which mimic activation and changes in rolipram inhibition triggered by protein kinase A phosphorylation of Ser-54: generation of a molecular model. in The Biochemical journal 1998
Show all 5 references for ABIN493277
findings identify PC2 (show CBX4 Antibodies) and PDE4C as unique components of an AKAP (show AKAP1 Antibodies) complex in primary cilia and reveal a common mechanism for dysregulation of cAMP signaling in cystic kidney diseases arising from different gene mutations
Data show that PDE4C is downregulated through promoter hypermethylation in glioma.
PDE4A (show PDE4A Antibodies) and PDE4C work in redundant fashion to mediate the loss of inhibitory PGE2 signaling in lung fibroblasts.
The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
cAMP-specific 3',5'-cyclic phosphodiesterase 4C
, phosphodiesterase 4C, cAMP-specific (phosphodiesterase E1 dunce homolog, Drosophila)
, phosphodiesterase 4C, cAMP-specific (phosphodiesterase E1 dunce homolog)
, phosphodiesterase E1 dunce homolog
, cAMP-specific 35-cyclic phosphodiesterase 4C