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anti-phosphodiesterase 6C, CGMP-Specific, Cone, alpha Prime (PDE6C) Antibodies

PDE6C encodes the alpha-prime subunit of cone phosphodiesterase, which is composed of a homodimer of two alpha-prime subunits and 3 smaller proteins of 11, 13, and 15 kDa. Additionally we are shipping and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PDE6C 110855 Q91ZQ1
PDE6C 361752  
PDE6C 5146 P51160
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Top anti-PDE6C Antibodies at antibodies-online.com

Showing 10 out of 28 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC (p), WB Immunohistochemistry analysis in formalin fixed and paraffin embedded brain tissue reacted with PDE6C Antibody (Center) followed by peroxidase conjugation of the secondary antibody and DAB staining. Western blot analysis of PDE6C Antibody (Center) in mouse liver tissue lysates (35ug/lane). PDE6C (arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of PDE6C Antibody (Center) (ABIN653683) in mouse liver tissue lysates (35 µg/lane). PDE6C (arrow) was detected using the purified polyclonal antibody. PDE6C Antibody (Center) (ABIN653683) IHC analysis in formalin fixed and paraffin embedded brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB   0.1 mg Log in to see 6 to 8 Days
$456.50
Details
Human Rabbit Alkaline Phosphatase (AP) IHC, ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated WB   50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated ELISA   200 μL Log in to see 8 to 10 Days
$713.17
Details
Human Rabbit Un-conjugated WB   100 μL Log in to see 8 to 10 Days
$793.83
Details
Human Mouse Un-conjugated ELISA, WB PDE6C polyclonal antibody (A01), Lot # 060116JC01 Western Blot analysis of PDE6C expression in HL-60 . Western Blot detection against Immunogen (36.89 KDa) . 50 μL Log in to see 9 Days
$298.57
Details
Human Rabbit Un-conjugated IHC, WB 400 μL Log in to see 6 Days
$457.14
Details

PDE6C Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine)



Rat (Rattus)



Human ,
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Top referenced anti-PDE6C Antibodies

  1. Human Polyclonal PDE6C Primary Antibody for IHC (p), WB - ABIN954067 : Mustafi, Maeda, Kohno, Nadeau, Palczewski: Inflammatory priming predisposes mice to age-related retinal degeneration. in The Journal of clinical investigation 2012 (PubMed)
    Show all 4 references for ABIN954067

  2. Cow (Bovine) Polyclonal PDE6C Primary Antibody for WB - ABIN493310 : Florio, Prusti, Beavo: Solubilization of membrane-bound rod phosphodiesterase by the rod phosphodiesterase recombinant delta subunit. in The Journal of biological chemistry 1996 (PubMed)
    Show all 2 references for ABIN493310

  3. Human Polyclonal PDE6C Primary Antibody for IHC (p), WB - ABIN653683 : Xu, Morris, Thapa, Ma, Michalakis, Biel, Baehr, Peshenko, Dizhoor, Ding: cGMP accumulation causes photoreceptor degeneration in CNG channel deficiency: evidence of cGMP cytotoxicity independently of enhanced CNG channel function. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2013 (PubMed)

More Antibodies against PDE6C Interaction Partners

Mouse (Murine) phosphodiesterase 6C, CGMP-Specific, Cone, alpha Prime (PDE6C) interaction partners

  1. A comprehensive in vivo assessment of retinal morphology and function was performed in cpfl1 (cone photoreceptor function loss 1) mice to better define the disease process in this model of cone dystrophies.

  2. the spontaneous mouse mutant cpfl1 that features a lack of cone function and rapid degeneration of the cone photoreceptors represents a homologous mouse model for PDE6C associated achromatopsia.

Human phosphodiesterase 6C, CGMP-Specific, Cone, alpha Prime (PDE6C) interaction partners

  1. A novel homozygous PDE6C mutation was identified as the cause of ACHM. In addition, we identified an OPN1SW (show OPN1SW Antibodies) mutation in the sibling with complete achromatopsia.

  2. The majority (n = 12) of patients were either homozygotes or compound heterozygotes for known achromatopsia alleles, two in CNGB3 (show CNGB3 Antibodies) (p.T383fsX and p.T296YfsX9) and three in CNGA3 (show CNGA3 Antibodies) (p.R283Q, p.R427C and p.L527R).

  3. analysis of amino acid residues responsible for the selectivity of tadalafil binding to two closely related phosphodiesterases, PDE5 (show PDE5A Antibodies) and PDE6

  4. Eleven different PDE6C mutations were found including two nonsense mutations, three mutations affecting transcript splicing as shown by minigene assays, one 1 bp-insertion and five missense mutations

  5. Homozygosity mapping reveals PDE6C mutations in patients with early-onset cone photoreceptor disorders.

  6. the identification of mutations in the PDE6C gene encoding the catalytic subunit of the cone photoreceptor phosphodiesterase as a cause of autosomal recessive achromatopsia was reported.

PDE6C Antigen Profile

Protein Summary

This gene encodes the alpha-prime subunit of cone phosphodiesterase, which is composed of a homodimer of two alpha-prime subunits and 3 smaller proteins of 11, 13, and 15 kDa. Mutations in this gene are associated with cone dystrophy type 4 (COD4).

Gene names and symbols associated with PDE6C

  • phosphodiesterase 6C, cGMP-specific, cone, alpha prime (PDE6C) antibody
  • phosphodiesterase 6C, cGMP specific, cone, alpha prime (Pde6c) antibody
  • ACHM5 antibody
  • COD4 antibody
  • cpfl1 antibody
  • PDE6C antibody
  • PDEA2 antibody

Protein level used designations for PDE6C

phosphodiesterase 6C, cGMP-specific, cone, alpha prime , cone cGMP phosphodiesterase-like , cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'-like , phosphodiesterase 6C, cGMP specific, cone, alpha prime , cyclic nucleotide phosphodiesterase 6c , cGMP phosphodiesterase 6C , cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' , PDE V-C1 , phosphodiesterase, cyclic GMP (cone receptor) , cone cGMP phosphodiesterase a'-subunit

GENE ID SPECIES
486805 Canis lupus familiaris
700261 Macaca mulatta
740456 Pan troglodytes
100343836 Oryctolagus cuniculus
100444869 Pongo abelii
100480480 Ailuropoda melanoleuca
100527954 Cavia porcellus
100597030 Nomascus leucogenys
110855 Mus musculus
361752 Rattus norvegicus
5146 Homo sapiens
281975 Bos taurus
395834 Gallus gallus
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