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The protein encoded by PDE9A catalyzes the hydrolysis of cAMP and cGMP to their corresponding monophosphates. Additionally we are shipping PDE9A Antibodies (52) and PDE9A Kits (2) and many more products for this protein.
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Human PDE9A Protein expressed in Baculovirus infected Insect Cells - ABIN2004746
Andreeva, Dikkes, Epstein, Rosenberg: Expression of cGMP-specific phosphodiesterase 9A mRNA in the rat brain. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2001
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Human PDE9A Protein expressed in Escherichia coli (E. coli) - ABIN2004744
Kruse, Møller, Tibaek, Gammeltoft, Olesen, Kruuse: PDE9A, PDE10A, and PDE11A expression in rat trigeminovascular pain signalling system. in Brain research 2009
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PDE9A can regulate cGMP signalling independent of the nitric oxide pathway, and its role in stress-induced heart disease suggests potential as a therapeutic target.
it is concluded that assessment of PDE5 (show PDE5A Proteins) and PDE9 expression may be useful in the differential diagnosis of benign and malignant breast disease and successful treatment of breast cancer
In vivo effects of PDE9A inhibition included reversal of the respective disruptions of working memory.
PDE9 is widely distributed in the urothelial epithelium of the human lower urinary tract and its potential roles may be different from those of PDE5 (show PDE5A Proteins).
Data show that PDE9A inhibitor, BAY-73-6691, significantly reduced basal and sickle cell (SCA) neutrophil adhesion; this was accompanied by decreased SCA neutrophil surface expressions of the L-selectin (show SELL Proteins) and CD11b (show ITGAM Proteins) adhesion molecules.
Identification and distribution of different variants produced by differential splicing of phosphodiesterase 9A mRNA.
The data suggests the utilization of two different start codons to produce a variety of different PDE9A proteins, allowing specific subcellular location of PDE9A splice variants.
PDE9A, is unlikely to play an important role in antidepressant outcome in this sample
The protein encoded by this gene catalyzes the hydrolysis of cAMP and cGMP to their corresponding monophosphates. The encoded protein plays a role in signal transduction by regulating the intracellular concentration of these cyclic nucleotides. Multiple transcript variants encoding several different isoforms have been found for this gene.
, phosphodiesterase 9a
, CGMP-specific 3',5'-cyclic phosphodiesterase type 9
, high affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A
, phosphodiesterase PDE9A21