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PCK1 is a main control point for the regulation of gluconeogenesis. Additionally we are shipping PCK1 Kits (17) and PCK1 Proteins (9) and many more products for this protein.
Showing 10 out of 184 products:
Human Polyclonal PCK1 Primary Antibody for IF, IHC (p) - ABIN1882180
OBrien, Printz, Halmi, Tiesinga, Granner: Structural and functional analysis of the human phosphoenolpyruvate carboxykinase gene promoter. in Biochimica et biophysica acta 1996
Show all 8 references for ABIN1882180
Human Polyclonal PCK1 Primary Antibody for EIA, IHC (p) - ABIN360565
Dunten, Belunis, Crowther, Hollfelder, Kammlott, Levin, Michel, Ramsey, Swain, Weber, Wertheimer: Crystal structure of human cytosolic phosphoenolpyruvate carboxykinase reveals a new GTP-binding site. in Journal of molecular biology 2002
Show all 3 references for ABIN360565
Chicken Polyclonal PCK1 Primary Antibody for WB - ABIN2777602
Chakravarty, Wu, Chiang, Samols, Hanson: SREBP-1c and Sp1 interact to regulate transcription of the gene for phosphoenolpyruvate carboxykinase (GTP) in the liver. in The Journal of biological chemistry 2004
Show all 2 references for ABIN2777602
Human Polyclonal PCK1 Primary Antibody for IHC (p), IHC - ABIN250970
Yang, Graham, Mody, Preitner, Peroni, Zabolotny, Kotani, Quadro, Kahn: Serum retinol binding protein 4 contributes to insulin resistance in obesity and type 2 diabetes. in Nature 2005
Dog (Canine) Polyclonal PCK1 Primary Antibody for IHC, WB - ABIN2777603
Hajarnis, Schroeder, Curthoys: 3'-Untranslated region of phosphoenolpyruvate carboxykinase mRNA contains multiple instability elements that bind AUF1. in The Journal of biological chemistry 2005
Cow (Bovine) Polyclonal PCK1 Primary Antibody for WB - ABIN2777601
Cadoudal, Glorian, Massias, Fouque, Forest, Benelli: Retinoids upregulate phosphoenolpyruvate carboxykinase and glyceroneogenesis in human and rodent adipocytes. in The Journal of nutrition 2008
Human Polyclonal PCK1 Primary Antibody for ELISA, WB - ABIN190801
Willer, Bonnycastle, Conneely, Duren, Jackson, Scott, Narisu, Chines, Skol, Stringham, Petrie, Erdos, Swift, Enloe, Sprau, Smith, Tong, Doheny, Pugh, Watanabe, Buchanan, Valle, Bergman, Tuomilehto et al.: Screening of 134 single nucleotide polymorphisms (SNPs) previously associated with type 2 diabetes replicates association with 12 SNPs in nine genes. ... in Diabetes 2006
Arabidopsis uses two gluconeogenic gateways for organic acids to fuel seedling establishment, one is via PCK1, and a second via PPDK.
Malate metabolism is important during dark-induced stomatal closure and that phosphoenolpyruvate carboxykinase (PEPCK) is involved in this process.
A mutation of PCK1 associated with Smith-Magenis Syndrome, cytosolic PEPCK (show PEPCK Antibodies) deficiency and NMDA receptor glutamate (show GRIN1 Antibodies) insensitivity.
Insulin (show INS Antibodies)-dependent translocation of FOXO1 (show FOXO1 Antibodies) regulated transcriptional repression of PCK1 concomitant with the formation of the FOXO1 (show FOXO1 Antibodies)-euchromatic histone-lysine N-methyltransferase2 (show DNMT1 Antibodies) (EHMT2 (show EHMT2 Antibodies)) complex and histone modifications of the PCK1 promoter region
Lipopolysaccharide and monophosphoryl lipid A also up-regulated G6PC (show G6PC Antibodies) and PCK1 transcript abundance in a TLR4 (show TLR4 Antibodies)-dependent manner.
The PCK1 tag-single nucleotide polymorphisms influenced insulin (show INS Antibodies) resistance by interacting with plasma n-3 polyunsaturated fatty acids levels in metabolic syndrome patients.
HCV core protein expression-mediated FOXO1 (show FOXO1 Antibodies) activation and the increased PGC-1alpha (show PPARGC1A Antibodies) leaded to the elevation of PCK1 at the mRNA level
Acetylation regulates the stability of the gluconeogenic rate-limiting enzyme PEPCK1.
Data show PEPCK-C and CPT-1 (show CPT1A Antibodies) mRNAs are more abundant in non-tumoral tissues than in the tumoral counterpart, whereas the opposite occurred for the FAS (show FAS Antibodies) gene.
Studies demonstrate the association between PCK1 and smaller average brain volume.
Study in the EYHS cohort failed to identify an association of PCK1 polymorphisms with obesity, physical activity, and fitness.
crystal structure of human cytosolic phosphoenolpyruvate carboxykinase reveals a new GTP-binding (show RND2 Antibodies) site
the renal proximal tubule, may require the remodeling of AUF1 (show HNRNPD Antibodies) binding to the elements that mediate the rapid turnover of PEPCK (show PEPCK Antibodies) mRNA
Collectively, the identified 3'-untranslated-region SNP variant highlights the importance of PCK1 in the fecundity of Holstein bulls, and implicates a role for bta-miR (show MYLIP Antibodies)-26a in regulating PCK1 abundance.
Expression of cytosolic PEPCK (show PEPCK Antibodies) mRNA is transiently increased during early lactation, indicating that enhanced hepatic gluconeogenesis during lactation may be tied to enhanced capacity for cytosolic formation of phosphoenolpyruvate.
Silencing PCK1 or inhibiting its enzymatic activity slows the growth of tumor-repopulating cells in vitro and impedes tumorigenesis in vivo.
PEPCK-M expression partially rescued defects in lipid metabolism, gluconeogenesis and TCA cycle function impaired by PEPCK-C deletion, while approximately 10% re-expression of PEPCK-C normalized most parameters.
FAT/CD36 (show CD36 Antibodies) regulates PEPCK (show PEPCK Antibodies) in adipose tissue and that this could be secondary to reductions in lipolysis.
PCB (show PC Antibodies) 126 blunted the forskolin-stimulated increase in phosphoenolpyruvate carboxykinase (PEPCK (show PEPCK Antibodies)) mRNA levels.
the role of IL-6 (show IL6 Antibodies) signalling in adipose tissue during exercise
there are multiple cytokine pathways by which inflammation inhibits PEPCK (show PEPCK Antibodies) expression in adipose tissue which could contribute to the increased mobilization of fatty acids during inflammation
Glucagon (show GCG Antibodies) can also regulate Pck1 in the intestine, but not in the kidneys.
Pck1 plays an important role in both the mammary gland adipocytes and epithelial cells during lactation
Results suggest that HDAC3 (show HDAC3 Antibodies) mediates NF-kappaB (show NFKB1 Antibodies) activity to repress Pepck (show PEPCK Antibodies) transcription.
Results show the effect of miR (show MLXIP Antibodies)-29a in counteracting insulin (show INS Antibodies) action on PEPCK (show PEPCK Antibodies) gene expression by primarily targeting PI3K and abrogating downstream insulin (show INS Antibodies) signaling in HepG2 cells.
The regulatory properties of maize phosphoenolpyruvate carboxylase were significantly altered by site-directed mutagenesis of residues 226 through 232.
This gene is a main control point for the regulation of gluconeogenesis. The cytosolic enzyme encoded by this gene, along with GTP, catalyzes the formation of phosphoenolpyruvate from oxaloacetate, with the release of carbon dioxide and GDP. The expression of this gene can be regulated by insulin, glucocorticoids, glucagon, cAMP, and diet. Defects in this gene are a cause of cytosolic phosphoenolpyruvate carboxykinase deficiency. A mitochondrial isozyme of the encoded protein also has been characterized.
, phosphoenol pyruvate carboxykinase
, phosphoenolpyruvate carboxy kinase
, phosphoenolpyruvate carboxykinase
, phosphoenolpyruvate carboxykinase, cytosolic
, phosphoenolpyruvate carboxykinase 1 (soluble)
, Phosphoenolpyruvate carboxykinase, cytosolic
, Phosphoenolpyruvate carboxykinase 1 (soluble)-like
, cytosolic phosphoenolpyruvate carboxykinase
, phosphoenolpyruvate carboxykinase, cytosolic [GTP]
, phosphoenolpyruvate carboxylase
, PEP carboxykinase
, phosphopyruvate carboxylase
, phosphoenolpyruvate carboxykinase 1 variant 1
, phosphoenolpyruvate carboxykinase 1 variant 2
, phosphoenolpyruvate carboxykinase 1 variant 3
, phosphoenolpyruvate carboxykinase 1 variant 4
, phosphoenolpyruvate carboxykinase 1 variant 5
, phosphoenolpyruvate carboxykinase (GTP)
, phosphoenolpyruvate carboxykinase 1, cytosolic
, phosphoenolpyruvate carboxykinase, cytosolic (GTP)
, gluconeogenic enzyme
, synonymous gene name: Pep2 in maize linkage map