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anti-phosphofurin Acidic Cluster Sorting Protein 2 (PACS2) Antibodies

Multifunctional sorting protein that controls the endoplasmic reticulum (ER)-mitochondria communication, including the apposition of mitochondria with the ER and ER homeostasis. Additionally we are shipping PACS2 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PACS2 23241 Q86VP3
PACS2 217893  
PACS2    
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Top anti-PACS2 Antibodies at antibodies-online.com

Showing 10 out of 24 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB WB Suggested Anti-PACS2 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: A549 cell lysate WB Suggested Anti-PACS2  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500  Positive Control: A549 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p), WB PACS2 Antibody (C-term) (ABIN657066) immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Biotin IHC, ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated IHC, WB 400 μL Log in to see 6 Days
$457.14
Details
Human Rabbit Un-conjugated IHC (p), ELISA   50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit APC IHC, ELISA, WB   200 μL Log in to see 16 Days
$710.29
Details
Human Rabbit FITC IHC, ELISA, WB   200 μL Log in to see 16 Days
$710.29
Details
Human Rabbit HRP IHC, ELISA, WB   200 μL Log in to see 16 Days
$710.29
Details
Human Rabbit PE IHC, ELISA, WB   200 μL Log in to see 16 Days
$710.29
Details
Human Rabbit Un-conjugated ELISA, WB   50 μL Log in to see 9 to 11 Days
$313.50
Details

PACS2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , ,


, , , , ,
Mouse (Murine)


Rat (Rattus)


Top referenced anti-PACS2 Antibodies

  1. Human Polyclonal PACS2 Primary Antibody for IHC (p), WB - ABIN657066 : Myhill, Lynes, Nanji, Blagoveshchenskaya, Fei, Carmine Simmen, Cooper, Thomas, Simmen: The subcellular distribution of calnexin is mediated by PACS-2. in Molecular biology of the cell 2008 (PubMed)
    Show all 2 references for ABIN657066

More Antibodies against PACS2 Interaction Partners

Human phosphofurin Acidic Cluster Sorting Protein 2 (PACS2) interaction partners

  1. cIAPs constitutively downregulate PACS-2 by polyubiquitination and proteasomal degradation, thereby restraining TRAIL-induced killing of liver cancer cells

  2. Tumor necrosis factor (show TNF Antibodies)-related apoptosis-inducing ligand (TRAIL) protein-induced lysosomal translocation of proapoptotic effectors is mediated by phosphofurin acidic cluster sorting protein-2.

  3. subcellular localization and function of polycystin-2 (show PKD2 Antibodies) are directed by phosphofurin acidic cluster sorting protein (PACS)-1 (show PACS1 Antibodies) and PACS-2

  4. PACS-2 as a novel sorting protein that links the endoplasmic reticulum (ER)-mitochondria axis to ER homeostasis

  5. PACS-2 is required for Nef action and sorting of itinerant membrane cargo in the TGN (show TG Antibodies)/endosomal system

  6. the phosphorylation state of the calnexin (show CANX Antibodies) cytosolic domain and its interaction with PACS-2 sort the chaperone between domains of the ER and the plasma membrane

  7. Results identify PACS-2 as an essential TRAIL effector, and show that Akt (show AKT1 Antibodies) cooperates with 14-3-3 (show YWHAQ Antibodies) to regulate the homeostatic and apoptotic properties of PACS-2 that mediate TRAIL action.

Mouse (Murine) phosphofurin Acidic Cluster Sorting Protein 2 (PACS2) interaction partners

  1. CS-2 (show MYOZ1 Antibodies) traffics to the nucleus where it regulates SIRT1 (show SIRT1 Antibodies)-mediated p53 (show TP53 Antibodies) deacetylation. PACS-2 binds SIRT1 (show SIRT1 Antibodies) in vitro and directly inhibits SIRT1 (show SIRT1 Antibodies)-catalyzed p53 (show TP53 Antibodies) deacetylation.

  2. PACS-2 is required for Nef action and sorting of itinerant membrane cargo in the TGN (show TG Antibodies)/endosomal system

  3. Results identify PACS-2 as an essential TRAIL effector, and show that Akt (show AKT1 Antibodies) cooperates with 14-3-3 (show YWHAQ Antibodies) to regulate the homeostatic and apoptotic properties of PACS-2 that mediate TRAIL action.

PACS2 Antigen Profile

Protein Summary

Multifunctional sorting protein that controls the endoplasmic reticulum (ER)-mitochondria communication, including the apposition of mitochondria with the ER and ER homeostasis. In addition, in response to apoptic inducer, translocates BIB to mitochondria, which initiates a sequence of events including the formation of mitochondrial truncated BID, the release of cytochrome c, the activation of caspase-3 thereby causing cell death. May also be involved in ion channel trafficking, directing acidic cluster-containing ion channels to distinct subcellular compartments.

Gene names and symbols associated with PACS2

  • phosphofurin acidic cluster sorting protein 2 (PACS2) antibody
  • phosphofurin acidic cluster sorting protein 2 (Pacs2) antibody
  • 6720425G15Rik antibody
  • AW208651 antibody
  • AW489976 antibody
  • E230011J22 antibody
  • mKIAA0602 antibody
  • PACS-2 antibody
  • Pacs1l antibody

Protein level used designations for PACS2

PACS1-like protein , PACS-2

GENE ID SPECIES
23241 Homo sapiens
217893 Mus musculus
Selected quality suppliers for anti-PACS2 (PACS2) Antibodies
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