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phosphoglycerate Mutase 1 (Brain) Proteins (PGAM1)

Phosphoglyceric acid mutase (EC 2.7.5.3) is widely distributed in mammalian tissues where it catalyzes the reversible reaction of 3-phosphoglycerate (3-PGA) to 2-phosphoglycerate (2-PGA) in the glycolytic pathway (summary by Chen et al., 1974 [PubMed 4811757]).[supplied by OMIM, Nov 2010].. Additionally we are shipping PGAM1 Antibodies (47) and PGAM1 Kits (24) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PGAM1 18648 Q9DBJ1
PGAM1 5223 P18669
PGAM1 24642 P25113
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Top PGAM1 Proteins at antibodies-online.com

Showing 10 out of 16 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag 100 μg Log in to see 7 to 8 Days
$319.00
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
$319.00
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,651.00
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,651.00
Details
Yeast Pongo abelii His tag   1 mg Log in to see 56 to 66 Days
$2,651.00
Details
HOST_Escherichia coli (E. coli) Human His tag   1 mg Log in to see 3 to 4 Days
$3,035.21
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 3 to 4 Days
$364.64
Details

PGAM1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , ,
,
Rat (Rattus)

Top referenced PGAM1 Proteins

  1. Mouse (Murine) PGAM1 Protein expressed in Escherichia coli (E. coli) - ABIN1098606 : Ballif, Carey, Sunyaev, Gygi: Large-scale identification and evolution indexing of tyrosine phosphorylation sites from murine brain. in Journal of proteome research 2008 (PubMed)
    Show all 2 references for ABIN1098606

  2. Human PGAM1 Protein expressed in Escherichia coli (E. coli) - ABIN667196 : Junien, Despoisse, Turleau, de Grouchy, Bucher, Fundele: Assignment of phosphoglycerate mutase (PGAMA) to human chromosome 10. Regional mapping of GOT1 and PGAMA to subbands 10q26.1 (or q25.3). in Annales de génétique 1982 (PubMed)
    Show all 2 references for ABIN667196

  3. Human PGAM1 Protein expressed in Wheat germ - ABIN1314779 : Kimura, Sakurai, Koumura, Yamada, Hayashi, Tanaka, Hozumi, Tanaka, Takemura, Seishima, Inuzuka: High prevalence of autoantibodies against phosphoglycerate mutase 1 in patients with autoimmune central nervous system diseases. in Journal of neuroimmunology 2010 (PubMed)

More Proteins for phosphoglycerate Mutase 1 (Brain) (PGAM1) Interaction Partners

Mouse (Murine) phosphoglycerate Mutase 1 (Brain) (PGAM1) interaction partners

  1. PGAM1 correlates with spermatogenic dysfunction and affects the function of cell proliferation, apoptosis and migration.

  2. 9630033F20Rik (show C12orf5 Proteins) may play an important role in muscle wasting and that it has a distinguished characterization of gene network.[9630033F20Rik (show C12orf5 Proteins)]

  3. histidine-phosphorylated PGAM1 correlated with expression of PKM2 in tumor tissues; decreased pyruvate kinase activity in PKM2-expressing cells allows PEP-dep (show PREP Proteins)endent histidine phosphorylation of PGAM1 and may provide an alternate glycolytic pathway

Human phosphoglycerate Mutase 1 (Brain) (PGAM1) interaction partners

  1. PGAM1 correlates with spermatogenic dysfunction and affects the function of cell proliferation, apoptosis and migration.

  2. Our finding showed that PGAM1 might serve as a promising therapeutic target for UBC (show RPS27A Proteins).

  3. PGAM1 is highly expressed in clear cell renal cell carcinoma (show MOK Proteins) and correlated with clinicalpathological features, which may contribute to tumor formation and progression.

  4. PGAM is acetylated at lysines 100/106/113/138 in its central region, and a member of the Sirtuin (show SIRT1 Proteins) family (class III deacetylase), SIRT2 (show SIRT2 Proteins), is responsible for its deacetylation.

  5. Tyrosine26 phosphorylation represents an additional acute mechanism underlying phosphoglycerate mutase 1 upregulation.

  6. Phosphoglycerate mutase 1 (PGAM1) contributes to biosynthesis regulation by controlling intracellular levels of its substrate, 3-phosphoglycerate (3-PG), and product, 2-phosphoglycerate (2-PG).

  7. PGAM1 deacetylation and activity are directly controlled by Sirt1 (show SIRT1 Proteins).

  8. histidine-phosphorylated PGAM1 correlated with expression of PKM2 in cancer cell lines; decreased pyruvate kinase activity in PKM2-expressing cells allows PEP (show PAEP Proteins)-dependent histidine phosphorylation of PGAM1 and may provide an alternate glycolytic pathway

  9. Our studies suggested that PGAM1 plays an important role in hepatocarcinogenesis

  10. Results identified phosphoglycerate mutase 1 that showed elevated levels of protein carbonyls in inferior parietal lobule (IPL (show PHLDA2 Proteins)) from subjects with early stage-Alzheimer's disease.

PGAM1 Protein Profile

Protein Summary

Phosphoglyceric acid mutase (EC 2.7.5.3) is widely distributed in mammalian tissues where it catalyzes the reversible reaction of 3-phosphoglycerate (3-PGA) to 2-phosphoglycerate (2-PGA) in the glycolytic pathway (summary by Chen et al., 1974

Gene names and symbols associated with PGAM1

  • phosphoglycerate mutase 1 (brain) (pgam1)
  • phosphoglycerate mutase 1 (brain) (PGAM1)
  • phosphoglycerate mutase 1 (LOC100350706)
  • phosphoglycerate mutase 1 (Pgam1)
  • phosphoglycerate mutase 1 (brain) (Pgam1)
  • phosphoglycerate mutase 1-like (LOC100352195)
  • phosphoglycerate mutase 1-like (LOC100154776)
  • 2310050F24Rik protein
  • MGC81450 protein
  • Pgam-1 protein
  • PGAM-B protein
  • PGAM1 protein
  • PGAMA protein
  • Pgmut protein

Protein level used designations for PGAM1

phosphoglycerate mutase 1 (brain) , phosphoglycerate mutase 1 , uncharacterized protein LOC706211 , BPG-dependent PGAM 1 , PGAM-B , phosphoglycerate mutase isozyme B , phosphoglycerate mutase A, nonmuscle form

GENE ID SPECIES
432058 Xenopus laevis
450650 Pan troglodytes
694418 Macaca mulatta
695799 Macaca mulatta
696959 Macaca mulatta
706211 Macaca mulatta
100144939 Xenopus (Silurana) tropicalis
100350706 Oryctolagus cuniculus
18648 Mus musculus
404148 Bos taurus
5223 Homo sapiens
24642 Rattus norvegicus
477786 Canis lupus familiaris
428969 Gallus gallus
100718830 Cavia porcellus
100174215 Pongo abelii
100352195 Oryctolagus cuniculus
100154776 Sus scrofa
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