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phosphoinositide-3-Kinase Adaptor Protein 1 (PIK3AP1) ELISA Kits

Involved in the activation of phosphoinositide 3-kinase (PI3K) in B-cells and in natural killer (NK) cells. Additionally we are shipping PIK3AP1 Antibodies (86) and PIK3AP1 Proteins (7) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
PIK3AP1 118788 Q6ZUJ8
PIK3AP1 83490 Q9EQ32
Anti-Rat PIK3AP1 PIK3AP1 294048  
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Top PIK3AP1 ELISA Kits at antibodies-online.com

Showing 3 out of 4 products:

Catalog No. Reactivity Sensitivity Range Quantity Supplier Delivery Price Details
Human 5.86 pg/ml 23.5-1500 pg/mL 96 Tests Log in to see 11 to 13 Days
$910.56
Details
Mouse
96 Tests Log in to see 11 to 13 Days
$875.60
Details
Chicken
96 Tests Log in to see 11 to 13 Days
$1,095.60
Details

More ELISA Kits for PIK3AP1 Interaction Partners

Human phosphoinositide-3-Kinase Adaptor Protein 1 (PIK3AP1) interaction partners

  1. Abi-1 (show ABI1 ELISA Kits) promotes Abl (show ABL1 ELISA Kits)-mediated BCAP (show PHF11 ELISA Kits) phosphorylation and suggest that Abi-1 (show ABI1 ELISA Kits) in general coordinates kinase-substrate interactions

Mouse (Murine) phosphoinositide-3-Kinase Adaptor Protein 1 (PIK3AP1) interaction partners

  1. Nck-mediated recruitment of BCAP to the BCR (show BCR ELISA Kits) regulates the PI(3 (show PI3 ELISA Kits))K-Akt (show AKT1 ELISA Kits) pathway in B cells.

  2. BCAP is an essential activator of the PI3K pathway downstream of TLR signaling.

  3. BCAP is a unique TIR domain-containing toll (show TLR4 ELISA Kits) like receptor (TLR) signaling adapter crucial for linking TLRs to PI3K activation and regulating the inflammatory response.

  4. As macrophages engage their pathogenic targets, innate immune receptors trigger increased expression of BCAP, which endows them with the capacity to withstand further challenges from ongoing cellular insults, such as endoplasmic reticulum stress.

  5. BCAP-(L) (but not BCAP-(S)) is a negative regulator of the TLR-mediated host defense system in macrophages.

  6. BCAP and CD19 have complementary roles in BCR-mediated phosphoinositide 3-kinase activation

  7. model in which blunting of BCAP-mediated activation signaling in developing NK cells promotes functionality, terminal maturation, and long-term survival

PIK3AP1 Antigen Profile

Antigen Summary

Involved in the activation of phosphoinositide 3-kinase (PI3K) in B-cells and in natural killer (NK) cells. Couples B-cell antigen receptor (BCR) to PI3K activation by providing a docking site for the PI3K subunit PIK3R1, which contributes to B-cell development. Seems to have a complementary role with CD19 in PI3K activation (By similarity). May be involved in the survival of mature B-cells via activation of REL (By similarity).

Gene names and symbols associated with PIK3AP1

  • phosphoinositide-3-kinase adaptor protein 1 (PIK3AP1) antibody
  • phosphoinositide-3-kinase adaptor protein 1 (Pik3ap1) antibody
  • 1810044J04Rik antibody
  • BCAP antibody
  • RP11-34E5.3 antibody

Protein level used designations for PIK3AP1

B cell adaptor protein , B-cell adapter for phosphoinositide 3-kinase , B-cell phosphoinositide 3-kinase adapter protein 1 , phosphoinositide 3-kinase adapter protein 1 , B cell phosphoinositide 3-kinase adaptor

GENE ID SPECIES
118788 Homo sapiens
83490 Mus musculus
294048 Rattus norvegicus
608653 Canis lupus familiaris
374268 Gallus gallus
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